Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Fatemeh Olang"'
Autor:
Wen Cai, Mary Hassani, Nicholas G. Hermann, Anthony S. Rose, Jennifer S. Lucas, Thomas J. Eads, Ervin D. Walter, Minoo Sedighi, Sahba Charkhzarrin, Katherine H. Koelsch, Mohammad Behforouz, Hamid Mirzaei, Fatemeh Olang, Howard D. Beall, Hassan Seradj, Rajesh Karki, Jayana P. Lineswala, Jeremy S. York
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:1899-1909
A series of lavendamycin analogues with two, three or four substituents at the C-6, C-7 N, C-2′, C-3′ and C-11′ positions were synthesized via short and efficient methods and evaluated as potential NAD(P)H:quinone oxidoreductase (NQO1)-directed
Autor:
Howard D. Beall, Jayana P. Lineswala, William Glen Holloway, Wen Cai, Fatemeh Olang, Mohammad Behforouz, John M. Gerdes, Katherine H. Koelsch, David C. Holley, Mary Hassani, Anthony S. Rose
Publikováno v:
Journal of Medicinal Chemistry. 51:3104-3115
A 1H69 crystal structure-based in silico model of the NAD(P)H:quinone oxidoreductase 1 (NQO1) active site has been developed to facilitate NQO1-directed lavendamycin antitumor agent development. Lavendamycin analogues were designed as NQO1 substrates
Autor:
Mary Hassani, Wen Cai, Katherine H. Koelsch, David C. Holley, Anthony S. Rose, Fatemeh Olang, Jayana P. Lineswala, William G. Holloway, John M. Gerdes, Mohammad Behforouz, Howard D. Beall
Publikováno v:
Journal of Medicinal Chemistry; May2008, Vol. 51 Issue 11, p3104-3115, 12p