Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Fatemeh Nematpour"'
Autor:
Saeedeh Ebadat, Samira Ahmadi, Maryam Ahmadi, Fatemeh Nematpour, Farzaneh Barkhordari, Reza Mahdian, Fatemeh Davami, Fereidoun Mahboudi
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185967 (2017)
In recent years, monoclonal antibodies (mAbs) have been developed as powerful therapeutic and diagnostic agents and Chinese hamster ovary (CHO) cells have emerged as the dominant host for the recombinant expression of these proteins. A critical step
Externí odkaz:
https://doaj.org/article/368a1bcc7e414d1ab8ebf8fc96d78a37
Autor:
Samira Ahmadi, Fatemeh Davami, Noushin Davoudi, Fatemeh Nematpour, Maryam Ahmadi, Saeedeh Ebadat, Kayhan Azadmanesh, Farzaneh Barkhordari, Fereidoun Mahboudi
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179902 (2017)
Establishing stable Chinese Hamster Ovary (CHO) cells producing monoclonal antibodies (mAbs) usually pass through the random integration of vectors to the cell genome, which is sensitive to gene silencing. One approach to overcome this issue is to ta
Externí odkaz:
https://doaj.org/article/8f006a93b32c458585607cdde419d74f
Autor:
Fatemeh Davami, Maryam Ahmadi, Fereidoun Mahboudi, Behrouz Vaziri, Samira Ahmadi, Fatemeh Nematpour, Vahid Khalaj, Saedeh Ebadat
Publikováno v:
Volume: 41, Issue: 4 622-628
Turkish Journal of Biology
Turkish Journal of Biology
Monoclonal antibodies (mAbs) are crucial in pharmaceutical biotechnology. Mammalian cell lines are the most preferred for their production. One of the significant challenging issues of mammalian expression systems is epigenetic gene silencing. Employ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fca6d12a1e54ed15705dae183d3a8f
https://doi.org/10.3906/biy-1702-18
https://doi.org/10.3906/biy-1702-18
Autor:
Reza Nasr, Maryam Ahmadi, Mojtaba Aghaeepoor, Fereidoun Mahboudi, Fatemeh Davami, Saeedeh Ebadat, Fatemeh Nematpour, Samira Ahmadi, Mohammad Reza Akbari Eidgahi
Publikováno v:
Biotechnology Progress. 32:1570-1576
Traditional methods to generate CHO cell lines rely on random integration(s) of the gene of interest and result in unpredictable and unstable protein expression. In comparison, site-specific recombination methods increase the recombinant protein expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c671a8ec9b98f47c3df699163d9cc7ee
https://doi.org/10.1002/btpr.2362
https://doi.org/10.1002/btpr.2362
Autor:
Farzaneh Barkhordari, Fatemeh Davami, Samira Ahmadi, Maryam Ahmadi, Saeedeh Ebadat, Kayhan Azadmanesh, Noushin Davoudi, Fereidoun Mahboudi, Fatemeh Nematpour
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 6, p e0179902 (2017)
PLoS ONE, Vol 12, Iss 6, p e0179902 (2017)
Establishing stable Chinese Hamster Ovary (CHO) cells producing monoclonal antibodies (mAbs) usually pass through the random integration of vectors to the cell genome, which is sensitive to gene silencing. One approach to overcome this issue is to ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e8f4a69e353ada9441828cc7dae8f1
http://europepmc.org/articles/PMC5491063
http://europepmc.org/articles/PMC5491063
Autor:
Samira Ahmadi, Fatemeh Davami, Vahid Khalaj, Fatemeh Nematpour, Fereidoun Mahboudi, Behrouz Vaziri, Maryam Ahmadi, Saedeh Ebadat
Publikováno v:
BMC Biotechnology
Background As the demand for monoclonal antibodies (mAb) increases, more efficient expression methods are required for their manufacturing process. Transcriptional gene silencing is a common phenomenon in recombinant cell lines which leads to express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9770a2376ec7697267fabd4013d663b8
https://doi.org/10.1186/s12896-017-0330-0
https://doi.org/10.1186/s12896-017-0330-0
Publikováno v:
Advanced Materials Research. 829:922-926
Hard carbon (HC) is a kind of carbon that is difficult to be graphitized and usually is fabricated from pyrolysis of polymers such as phenolic resins, epoxy resins and pitch. From the structural point of view, HC is highly irregular and disordered, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73dc30160625943ef7512df4a2a7a391
https://doi.org/10.4028/www.scientific.net/amr.829.922
https://doi.org/10.4028/www.scientific.net/amr.829.922
Autor:
Maryam Ahmadi, Fereidoun Mahboudi, Samira Ahmadi, Fatemeh Nematpour, Saeedeh Ebadat, Mohammad Reza Akbari Eidgahi, Fatemeh Davami
Publikováno v:
Protein expression and purification. 134
Objectives Several types of expression vectors have been used for recombinant protein expression in Chinese hamster ovary cells (CHO) which usually result in variable and unstable levels of expression. Methods and results In this study, we have compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9bfd4a5c463e20e66485971d351e9fb
https://pubmed.ncbi.nlm.nih.gov/28400295
https://pubmed.ncbi.nlm.nih.gov/28400295
Autor:
Maryam Ahmadi, Saeedeh Ebadat, Fatemeh Davami, Fatemeh Nematpour, Fereidoun Mahboudi, Reza Mahdian, Farzaneh Barkhordari, Samira Ahmadi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0185967 (2017)
PLoS ONE, Vol 12, Iss 10, p e0185967 (2017)
In recent years, monoclonal antibodies (mAbs) have been developed as powerful therapeutic and diagnostic agents and Chinese hamster ovary (CHO) cells have emerged as the dominant host for the recombinant expression of these proteins. A critical step
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9fcda67afc69c1b6de8796c2c448262
https://pubmed.ncbi.nlm.nih.gov/29023479
https://pubmed.ncbi.nlm.nih.gov/29023479
Publikováno v:
Tehran University, Kish International Campus, Kish Island, Iran
Background: Seas and oceans have been recognized as a rich source of metabolites and bioactive compounds with biodiversity and drug activity. These compounds have accumulated in various organisms. Bioactive compounds can be extracted from various ani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816579015d4659753eb4cfa464e0e1b2
https://doi.org/10.17795/jjnpp-32422
https://doi.org/10.17795/jjnpp-32422