Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Fatemeh Keramatnia"'
Autor:
Manish K. Tripathi, Chidi Zacheaus, Kyle Doxtater, Fatemeh Keramatnia, Cuilan Gao, Murali M. Yallapu, Meena Jaggi, Subhash C. Chauhan
Publikováno v:
Non-Coding RNA, Vol 4, Iss 3, p 20 (2018)
Formalin-fixed paraffin embedded (FFPE) tissues are a valuable resource for biomarker discovery in order to understand the etiology of different cancers and many other diseases. Proteins are the biomarkers of interest with respect to FFPE tissues as
Externí odkaz:
https://doaj.org/article/32b9beba6681439285094037d724b798
Autor:
Yunchao Chang, Fatemeh Keramatnia, Pankaj S Ghate, Gisele Nishiguchi, Qingsong Gao, Ilaria Iacobucci, Lei Yang, Divyabharathi Chepyala, Ashutosh Mishra, Anthony Andrew High, Hiroaki Goto, Koshi Akahane, Junmin Peng, Jun J. Yang, Marcus Fischer, Zoran Rankovic, Charles G. Mullighan
Publikováno v:
Blood Journal.
Advancing cure rates for high-risk acute lymphoblastic leukemia (ALL) has been limited by the lack of agents that effectively kill leukemic cells sparing normal hematopoietic tissue. Molecular glues direct the cellular ubiquitin ligase cellular machi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3f9dcbc1177fd7dd3a836a45891febf
https://doi.org/10.1182/blood.2022017813
https://doi.org/10.1182/blood.2022017813
Autor:
Mladen Koravovic, Anand Mayasundari, Gordana Tasic, Fatemeh Keramatnia, Timothy R. Stachowski, Huarui Cui, Sergio C. Chai, Barbara Jonchere, Lei Yang, Yong Li, Xiang Fu, Ryan Hiltenbrand, Leena Paul, Vibhor Mishra, Jeffery M. Klco, Martine F. Roussel, William CK. Pomerantz, Marcus Fischer, Zoran Rankovic, Vladimir Savic
Publikováno v:
European Journal of Medicinal Chemistry
An X-ray structure of a CLICK chemistry-based BET PROTAC bound to BRD2(BD2) inspired synthesis of JQ1 derived heterocyclic amides. This effort led to the discovery of potent BET inhibitors displaying overall improved profiles when compared to JQ1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5648b26b4c7d2361e3341b7c58a3cd9
https://farfar.pharmacy.bg.ac.rs/handle/123456789/4513
https://farfar.pharmacy.bg.ac.rs/handle/123456789/4513
Autor:
Richard E. Lee, Jake Slavish, Brandon Young, Lei Yang, Sergio C. Chai, Marcus Fischer, Taosheng Chen, Zhenmei Li, Stephen W. White, Stanley Nithianantham, Jaeki Min, Gisele Nishiguchi, Seung Wook Yang, Patrick Ryan Potts, Marisa Actis, Shalandus H. Garrett, Jamie Jarusiewicz, Sourav Das, Martine F. Roussel, Barbara Jonchere, Anand Mayasundari, Yong Li, Mi-Kyung Yun, Xiang Fu, Fatemeh Keramatnia, Anang A. Shelat, Zoran Rankovic
Publikováno v:
Angew Chem Int Ed Engl
Targeting cereblon (CRBN) is currently one of the most frequently reported proteolysis-targeting chimera (PROTAC) approaches, owing to favorable drug-like properties of CRBN ligands, immunomodulatory imide drugs (IMiDs). However, IMiDs are known to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ffb235e447bf310701a7f1aa84dd193
https://doi.org/10.1002/anie.202108848
https://doi.org/10.1002/anie.202108848
Autor:
Zoran Rankovic, Barbara Jonchere, Junmin Peng, Martine F. Roussel, Anand Mayasundari, Sourav Das, Gisele Nishiguchi, Shalandus H. Garrett, Shondra Miller, Jeanine E. Price, Kiran Kodali, Fatemeh Keramatnia, Divyabharathi Chepyala, Lei Yang, James B Papizan, Jaeki Min, Marcus Fischer, P. Jake Slavish, Marisa Actis, Kevin McGowan, Charles G. Mullighan, Yong Li, Xiang Fu, Jamie Jarusiewicz, Brandon Young, Yunchao Chang
Publikováno v:
Journal of Medicinal Chemistry
Whereas the PROTAC approach to target protein degradation greatly benefits from rational design, the discovery of small-molecule degraders relies mostly on phenotypic screening and retrospective target identification efforts. Here, we describe the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666941d34c5223c407c9284840558645
https://doi.org/10.1021/acs.jmedchem.0c01313
https://doi.org/10.1021/acs.jmedchem.0c01313
Autor:
Subhash C. Chauhan, Kyle Doxtater, Meena Jaggi, Fatemeh Keramatnia, Manish K. Tripathi, Chidi Zacheaus, Murali M. Yallapu
Publikováno v:
Drug Discovery Today. 23:1635-1643
Long noncoding RNAs (lncRNAs) are a class of noncoding RNA, involved in regulation of diverse physiological and pathological processes. Ovarian cancer is the leading cause of death among all gynecological malignancies in the world and its underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75411389c4ae36e29d13b23d0bc2d663
https://doi.org/10.1016/j.drudis.2018.04.010
https://doi.org/10.1016/j.drudis.2018.04.010
Autor:
Fatemeh Keramatnia, Yunchao Chang, Gisele Nishiguchi, Jaeki Min, Charles Mullighan, Marcus Fischer, Zoran Rankovic
Publikováno v:
Molecular Cancer Therapeutics. 20:LBA002-LBA002
Acute Lymphoblastic Leukemia (ALL), the most common childhood cancer and the second most common acute leukemia in adults, arises from clonal expansion of undifferentiated lymphoid precursor cells in bone marrow. Although the majority of childhood ALL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64a271a6259917e46ed6c7e0daf088d4
https://doi.org/10.1158/1535-7163.targ-21-lba002
https://doi.org/10.1158/1535-7163.targ-21-lba002
Publikováno v:
Fluid Phase Equilibria. 425:108-113
Solid forms of drugs have some potential problems such as low solubility, slow dissolution rate, variable bioavailability and polymorphism. One of the strategies to overcome these problems is the preparation of ionic liquid forms of drugs. Recently,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d606e745cb8f1d7e8e5d04e6a0f9cb71
https://doi.org/10.1016/j.fluid.2016.05.016
https://doi.org/10.1016/j.fluid.2016.05.016
Autor:
Murali M. Yallapu, Manish K. Tripathi, Kyle Doxtater, Cuilan Gao, Chidi Zacheaus, Subhash C. Chauhan, Meena Jaggi, Fatemeh Keramatnia
Publikováno v:
Non-Coding RNA
Volume 4
Issue 3
Non-Coding RNA, Vol 4, Iss 3, p 20 (2018)
Volume 4
Issue 3
Non-Coding RNA, Vol 4, Iss 3, p 20 (2018)
Formalin-fixed paraffin embedded (FFPE) tissues are a valuable resource for biomarker discovery in order to understand the etiology of different cancers and many other diseases. Proteins are the biomarkers of interest with respect to FFPE tissues as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af96a1f040607f3f02beae136b4a3fed
http://europepmc.org/articles/PMC6162476
http://europepmc.org/articles/PMC6162476
Autor:
Fatemeh Keramatnia, Mehdi Chaib, Kyle Doxtater, Manish Triparthi, Chidi Zacheaus, Subhash C. Chauhan
Publikováno v:
Cancer Research. 79:2647-2647
Colorectal Cancer(CRC) is one of the leading cause of cancer related death in the United States today in both men and women. With an expected 50,260 deaths in 2017 it is the second leading cause of cancer related deaths among men and the third among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3d01700495c6cb2edd5769d55bc508f
https://doi.org/10.1158/1538-7445.am2019-2647
https://doi.org/10.1158/1538-7445.am2019-2647