Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Fatemeh Dubois"'
Publikováno v:
Molecular Biology of the Cell. 34
The role of the focal adhesion adaptor paxillin in regulating the Rab5 GTPase is evaluated. Paxillin, through modulation of HDAC6 activity and thereby microtubule acetylation, was shown to regulate Rab5 activity, as well as Rab5-associated vesicle di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4ebcdbe5da5f6035d2184f500c94c64
https://doi.org/10.1091/mbc.e22-10-0455
https://doi.org/10.1091/mbc.e22-10-0455
Autor:
Jérôme Levallet, Tiphaine Biojout, Céline Bazille, Manon Douyère, Fatéméh Dubois, Dimitri Leite Ferreira, Jasmine Taylor, Sylvain Teulier, Jérôme Toutain, Nicolas Elie, Myriam Bernaudin, Samuel Valable, Emmanuel Bergot, Guénaëlle Levallet
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-13 (2023)
Abstract The molecular mechanisms induced by hypoxia are misunderstood in non-small cell lung cancer (NSCLC), and above all the hypoxia and RASSF1A/Hippo signaling relationship. We confirmed that human NSCLC (n = 45) as their brain metastases (BM) co
Externí odkaz:
https://doaj.org/article/314a3a44fb5749b79b75d1af5f9ad218
Publikováno v:
Molecular Biology of the Cell
By modulating microtubule acetylation, a paxillin and focal adhesion kinase signaling cassette controls Golgi and centrosome organization as well as polarization of both organelles toward the leading edge. Paxillin accumulation at the centrosome is F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad5d46fbd01b21fedef3825651d5c3c
http://europepmc.org/articles/PMC5739297
http://europepmc.org/articles/PMC5739297
Autor:
Christopher E. Turner, Gregory J. Goreczny, Anushree C. Gulvady, Nicholas O. Deakin, Fatemeh Dubois
Publikováno v:
Molecular biology of the cell. 29(13)
The focal adhesion proteins Hic-5 and paxillin have been previously identified as key regulators of MDA-MB-231 breast cancer cell migration and morphologic mesenchymal-amoeboid plasticity in three-dimensional (3D) extracellular matrices (ECMs). Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80abb7fc1a39ab919f6c9fd4c17937a
https://pubmed.ncbi.nlm.nih.gov/29771639
https://pubmed.ncbi.nlm.nih.gov/29771639
Autor:
Maureen Keller, Fatéméh Dubois, Sylvain Teulier, Alexandre P. J. Martin, Jérôme Levallet, Elodie Maille, Solenn Brosseau, Nicolas Elie, Alexander Hergovich, Emmanuel Bergot, Jacques Camonis, Gérard Zalcman, Guénaëlle Levallet
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Abstract Background RASSF1A, a tumor suppressor gene, is frequently inactivated in lung cancer leading to a YAP-dependent epithelial-mesenchymal transition (EMT). Such effects are partly due to the inactivation of the anti-migratory RhoB GTPase via t
Externí odkaz:
https://doaj.org/article/c6c2ffc895a741f4a83085207c1ce502
A role for RASSF1A in tunneling nanotube formation between cells through GEFH1/Rab11 pathway control
Autor:
Fatéméh Dubois, Bastien Jean-Jacques, Hélène Roberge, Magalie Bénard, Ludovic Galas, Damien Schapman, Nicolas Elie, Didier Goux, Maureen Keller, Elodie Maille, Emmanuel Bergot, Gérard Zalcman, Guénaëlle Levallet
Publikováno v:
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-20 (2018)
Abstract Background By allowing intercellular communication between cells, tunneling nanotubes (TNTs) could play critical role in cancer progression. If TNT formation is known to require cytoskeleton remodeling, key mechanism controlling their format
Externí odkaz:
https://doaj.org/article/e2009b66732b400eab325f968b7cf09c
Autor:
Emmanuel Bergot, Guénaëlle Levallet, Karine Campbell, Fatéméh Dubois, Emmanuèle Lechapt, Gérard Zalcman
Publikováno v:
European Respiratory Review, Vol 22, Iss 130, Pp 565-576 (2013)
The aim of this article is to summarise the published data on prognostic and predictive biomarkers for early-stage non-small cell lung cancer (NSCLC), and discuss how to integrate them into clinical trials. Large phase III trials have been published
Externí odkaz:
https://doaj.org/article/54a1752831b84ca18c6e946053a676fd