Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Fatema Z. Chowdhury"'
Autor:
Christine D. Palmer, Meghan G. Hart, Sonia Kounlavouth, Harshni Venkatraman, Lauren D. Kraemer, Martina Marrali, Calixto Dominguez, Fatema Z. Chowdhury, Jason R. Jaroslavsky, Lindsey Arcebuche, Lorenzo Hernandez, Bukola Adeoye, Severino Cuison, Amy R. Rappaport, Greg Boucher, Monica Lane, Melissa Rotunno, Kenneth Avocetien, Leiliane Sousa, Chris Puccia, Molly Likes, Rahul Vegesna, Rita Zhou, Alexis Mantilla, Matthew J. Davis, Ankur Dhanik, Melissa Johnson, Andrew R. Ferguson, Karin Jooss
Publikováno v:
Cancer Research. 83:2267-2267
Mutations in the KRAS gene are among the most common driver mutations in cancer. Targeting KRAS G12C mutations has shown some promise in clinical studies, though acquired resistance mutations pose a challenge for small molecule-based monotherapies. V
Autor:
Mathias Lichterfeld, Kevin Einkauf, Xu G. Yu, Jonathan Z. Li, Fatema Z. Chowdhury, Guinevere Q. Lee, Xiaoming Sun, Stephane Hua, Ce Gao, Xiao-Dong Lian, Tae-Wook Chun, Samantha M.Y. Chen, Eric S. Rosenberg, Radwa Sharaf, Chenyang Jiang
Publikováno v:
Journal of Clinical Investigation. 129:988-998
Chromosomal integration of genome-intact HIV-1 sequences into the host genome creates a reservoir of virally infected cells that persists throughout life, necessitating indefinite antiretroviral suppression therapy. During effective antiviral treatme
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92187 (2014)
CD8+ cytotoxic T lymphocytes (CTLs) play a major role in defense against intracellular pathogens. During development, antigen-presenting cells secrete innate cytokines such as IL-12 and IFN-α, which drive CTL differentiation into diverse populations
Externí odkaz:
https://doaj.org/article/e75e0cb837b342f4928fb3beb1de54d6
Autor:
Amy M Becker, Kathryn H Dao, Bobby Kwanghoon Han, Roger Kornu, Shuchi Lakhanpal, Angela B Mobley, Quan-Zhen Li, Yun Lian, Tianfu Wu, Andreas M Reimold, Nancy J Olsen, David R Karp, Fatema Z Chowdhury, J David Farrar, Anne B Satterthwaite, Chandra Mohan, Peter E Lipsky, Edward K Wakeland, Laurie S Davis
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67003 (2013)
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is characterized by defective immune tolerance combined with immune cell hyperactivity resulting in the production of pathogenic autoantibodies. Previous gene expression studies
Externí odkaz:
https://doaj.org/article/fa7ba6fef3494bf898048d039e41f0e6
Autor:
Hugues Allard-Chamard, Bruce D. Walker, Jared Feldman, Eric C. Koscher, Jonathan Z. Li, Libera Sessa, Aaron G. Schmidt, Kelsey K. Finn, Hang Liu, Fatema Z. Chowdhury, Pilar Garcia-Broncano, Daniel Lingwood, Jinqing Liu, Xiao-Dong Lian, Ciputra Adijaya Hartana, Ashlin R. Michell, Alex Lee Zhu, Naoki Kaneko, Kevin Einkauf, Ngoc L. Ly, Vinay Mahajan, Xiaoming Sun, Robert F. Padera, Jocelyn R. Farmer, Chenyang Jiang, Paulina Kaplonek, Yelizaveta Rassadkina, Nathalie Bonheur, Shiv Pillai, Timothy M. Caradonna, Hannah J. Ticheli, Marshall Karpell, Sally Shin, Jon Fallon, Julie Boucau, Kristina Lefteri, Josh Chevalier, Kyra Seiger, Mathias Lichterfeld, Alicja Piechocka-Trocha, Nishant K. Singh, Hsiao-Hsuan Kuo, Blake M. Hauser, Weiwei Sun, Matthew Osborn, Yannic C. Bartsch, Michael T. Waring, Thomas J. Diefenbach, Xu G. Yu, Galit Alter, Julia Bals
Publikováno v:
Cell
Summary Humoral responses in COVID-19 disease are often of limited durability, as seen with other human coronavirus epidemics. To address the underlying etiology, we examined postmortem thoracic lymph nodes and spleens in acute SARS-CoV-2 infection a
Autor:
Bruce D. Walker, Alex Lee Zhu, Eric C. Koscher, Xiao-Dong Lian, Sally Shin, Matthias Lichterfeld, Jocelyn R. Farmer, Jon Fallon, Kristina Lefteri, Marshall Karpell, Josh Chevalier, Yelizaveta Rassadkina, Shiv Pillai, Hannah J. Ticheli, Julie Boucau, Vinay Mahajan, Thomas J. Diefenbach, Hugues Allard-Chamard, Ashlin R. Michell, Kelsey K. Finn, Xu G. Yu, Hsiao-Hsuan Kuo, Ciputra Adijaya Hartana, Blake M. Hauser, Michael T. Waring, Jinqing Liu, Daniel Lingwood, Julia Bals, Robert F. Padera, Kevin Einkauf, Matt Osborn, Weiwei Sun, Naoki Kaneko, Ngoc L. Ly, Yannic C. Bartsch, Jared Feldman, Jonathan Z. Li, Kyra Seiger, Hang Liu, Pilar Garcia-Broncano, Alicja Piechocka-Trocha, Nishant K. Singh, Timothy M. Caradonna, Libera Sessa, Aaron G. Schmidt, Nathalie Bonheur, Chenyang Jiang, Paulina Kaplonek, Fatema Z. Chowdhury, Xiaoming Sun
Publikováno v:
SSRN
Humoral responses in COVID-19 disease are often of limited durability, as seen with other human coronavirus epidemics. To address the underlying etiology, we examined postmortem thoracic lymph nodes and spleens in acute SARS-CoV-2 infection and obser
Autor:
Mathias Lichterfeld, Kathleen M. Powis, Joseph Makhema, Pilar Garcia-Broncano, Xu G. Yu, Thabani Ncube, Patrick Jean-Philippe, Chenyang Jiang, Daniel R. Kuritzkes, Ce Gao, Terence Mohammed, Kevin Einkauf, Shivaali Maddali, Joshua M. Chevalier, Gbolahan Ajibola, Sikhulile Moyo, Shahin Lockman, Kenneth Maswabi, Fatema Z. Chowdhury, Roger L. Shapiro
Publikováno v:
Sci Transl Med
Neonatal HIV-1 infection is associated with rapidly progressive and frequently fatal immune deficiency if left untreated. Immediate institution of antiretroviral therapy (ART), ideally within hours after birth, may restrict irreversible damage to the
Autor:
Fatema Z. Chowdhury, Sean Harrington, Xiaoming Sun, Eric S. Rosenberg, Xu G. Yu, Nina Orlova-Fink, Mathias Lichterfeld
Publikováno v:
AIDS. 31:2211-2215
Objective The functional polarization of CD4 T cells determines their antimicrobial effector profile, but may also impact the susceptibility to infection with HIV-1. Here, we analyzed the susceptibility of CD4 T cells with different functional polari
Autor:
Sean Harrington, Bruce D. Walker, Hsiao-Rong Chen, Krista L. Dong, Kavidha Reddy, Nina Orlova-Fink, Thumbi Ndung'u, Xu G. Yu, Stephane Hua, Fatema Z. Chowdhury, Kevin Einkauf, Hsiao-Hsuan Kuo, Xiaoming Sun, Guinevere Q. Lee, Mathias Lichterfeld, Eric S. Rosenberg, Zhengyu Ouyang
Publikováno v:
Journal of Clinical Investigation
HIV-1 causes a chronic, incurable disease due to its persistence in CD4+ T cells that contain replication-competent provirus, but exhibit little or no active viral gene expression and effectively resist combination antiretroviral therapy (cART). Thes
Autor:
Selena Vigano, Jordi J. Negrón, Samantha Tse, Xu G. Yu, Fatema Z. Chowdhury, Mathias Lichterfeld
Publikováno v:
AIDS. 31:207-212
OBJECTIVE(S) To assess the frequency and function of HIV-1-specific HLA-G (histocompatibility antigen class I, G) CD8 T cells in HIV-1 controllers and progressors. DESIGN We performed an observational cross-sectional cohort analysis in untreated (n =