Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Fatema Currim"'
1
Akademický článek
TNF-α differentially modulates subunit levels of respiratory electron transport complexes of ER/PR +ve/−ve breast cancer cells to regulate mitochondrial complex activity and tumorigenic potential
Autor: Anjali Shinde, Hyeryeon Jung, Hayun Lee, Kritarth Singh, Milton Roy, Dhruv Gohel, Han Byeol Kim, Minal Mane, Hitesh Vasiyani, Fatema Currim, Yu Ri Seo, Seojin Yang, Ara Cho, Eugene C. Yi, Rajesh Singh
Publikováno v: Cancer & Metabolism, Vol 9, Iss 1, Pp 1-15 (2021)
Abstract Background Tumor necrosis factor-α (TNF-α) is an immunostimulatory cytokine that is consistently high in the breast tumor microenvironment (TME); however, its differential role in mitochondrial functions and cell survival in ER/PR +ve and
Externí odkaz: https://doaj.org/article/97b7af9f07ec4e83857bc19075a6d5ef
Zobrazit plný text záznamu
3
DNA damage induces STING mediated IL-6-STAT3 survival pathway in triple-negative breast cancer cells and decreased survival of breast cancer patients
Autor: Hitesh Vasiyani, Minal Mane, Khushboo Rana, Anjali Shinde, Milton Roy, Jyoti Singh, Dhruv Gohel, Fatema Currim, Ratika Srivastava, Rajesh Singh
Publikováno v: Apoptosis : an international journal on programmed cell death. 27(11-12)
Triple-negative breast cancer is aggressive and metastatic breast cancer type and shows immune evasion, drug resistance, relapse and poor survival. Anti-cancer therapy like ionizing radiation and chemotherapeutic drug majorly induces DNA damage hence
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e45e2d951890402532353bb364181c
https://pubmed.ncbi.nlm.nih.gov/36018392
Zobrazit plný text záznamu
4
The analog of cGAMP, c-di-AMP, activates STING mediated cell death pathway in estrogen-receptor negative breast cancer cells
Autor: Minal Mane, Hitesh Vasiyani, Rajesh Singh, Kritarth Singh, Jyoti Singh, Fatema Currim, Anjali Shinde, Milton Roy, Dhruv Gohel, Mahesh Chhabria, Khushali Vaidya
Publikováno v: Apoptosis. 26:293-306
Immune adaptor protein like STING/MITA regulate innate immune response and plays a critical role in inflammation in the tumor microenvironment and regulation of metastasis including breast cancer. Chromosomal instability in highly metastatic cells re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2075cda799751bcf22ce85154816af3
https://doi.org/10.1007/s10495-021-01669-x
Zobrazit plný text záznamu
5
TNF-α-induced E3 ligase, TRIM15 inhibits TNF-α-regulated NF-κB pathway by promoting turnover of K63 linked ubiquitination of TAK1
Autor: Milton Roy, Kritarth Singh, Anjali Shinde, Jyoti Singh, Minal Mane, Sawani Bedekar, Yamini Tailor, Dhruv Gohel, Hitesh Vasiyani, Fatema Currim, Rajesh Singh
Publikováno v: Cellular signalling. 91
Ubiquitin E3-ligases are recruited at different steps of TNF-α-induced NF-κB activation; however, their role in temporal regulation of the pathway remains elusive. The study systematically identified TRIMs as potential feedback regulators of the TN
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b8e109a2eafab3486d8396040dfb3e
https://pubmed.ncbi.nlm.nih.gov/34871740
Zobrazit plný text záznamu
6
Expression of expanded FMR1-CGG repeats alters mitochondrial miRNAs and modulates mitochondrial functions and cell death in cellular model of FXTAS
Autor: Paresh Prajapati, Lakshmi Sripada, Darshan Kotadia, Milton Roy, Dhruv Gohel, Nicolas Charlet-Berguerand, Minal Mane, Kritarth Singh, Flora Tassone, Anjali Shinde, Rajesh Singh, Fatema Currim
Publikováno v: Free Radical Biology and Medicine
Free Radical Biology and Medicine, Elsevier, 2021, 165, pp.100-110. ⟨10.1016/j.freeradbiomed.2021.01.038⟩
Fragile X-associated tremor/ataxia syndrome (FXTAS) is a progressive neurodegenerative disorder caused by an expansion of 55 to 200 CGG repeats located within 5′UTR of FMR1.These CGG repeats are transcribed into RNAs, which sequester several RNA bi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9cb356662632b53245c833598e4c23d
https://hal.archives-ouvertes.fr/hal-03339492
Zobrazit plný text záznamu
8
TNF-α differentially modulates subunit levels of respiratory electron transport complexes of ER/PR +ve/-ve breast cancer cells to regulate mitochondrial complex activity and tumorigenic potential
Autor: Milton Roy, Dhruv Gohel, Ara Cho, Minal Mane, Rajesh Singh, Fatema Currim, Kritarth Singh, Seojin Yang, Hayun Lee, Han Byeol Kim, Anjali Shinde, Yu Ri Seo, Eugene C. Yi, Hitesh Vasiyani, Hyeryeon Jung
Publikováno v: Cancer & Metabolism
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-15 (2021)
Background Tumor necrosis factor-α (TNF-α) is an immunostimulatory cytokine that is consistently high in the breast tumor microenvironment (TME); however, its differential role in mitochondrial functions and cell survival in ER/PR +ve and ER/PR −
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0bb264d8fe1f78b568a28ed4fcce9d
https://pubmed.ncbi.nlm.nih.gov/33926547
Zobrazit plný text záznamu
9
Exosome Release Is Modulated by the Mitochondrial-Lysosomal Crosstalk in Parkinson's Disease Stress Conditions
Autor: Jyoti Singh, Shatakshi Shukla, Rajesh Singh, Anjali Shinde, Fatema Currim, Minal Mane, Hitesh Vasiyani, Milton Roy, Dhruv Gohel, Kritarth Singh
Publikováno v: Molecular neurobiology. 58(4)
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra (SN) pars compacta region of the brain. The main pathological hallmark involves cytoplasmic inclusions of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb7dfd817dbd4dca56951e0a6e6410f
https://pubmed.ncbi.nlm.nih.gov/33404982
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje