Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Fatema Al-rashed"'
Autor:
Hossein Arefanian, Sardar Sindhu, Fatema Al-Rashed, Fawaz Alzaid, Ashraf Al Madhoun, Mohammed Qaddoumi, Fatemah Bahman, Michayla R. Williams, Shaima Albeloushi, Nourah Almansour, Rasheed Ahmad, Fahd Al-Mulla
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionFamilial hypercholesterolemia, the highly prevalent form of dyslipidemia, is a well-known risk factor for premature heart disease and stroke worldwide. Statins, which inhibit 3-hydroxy 3-methylglutaryl coenzyme A (HMG-CoA) reductase, are
Externí odkaz:
https://doaj.org/article/87511eb9a7044e638e1a0ad8313264b5
Autor:
Fatemah Bahman, Khubaib Choudhry, Fatema Al-Rashed, Fahd Al-Mulla, Sardar Sindhu, Rasheed Ahmad
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The aryl hydrocarbon receptor (AhR) is a versatile environmental sensor and transcription factor found throughout the body, responding to a wide range of small molecules originating from the environment, our diets, host microbiomes, and internal meta
Externí odkaz:
https://doaj.org/article/4e0144c1dbbb494c8b09a0a96856fe6e
Autor:
Texy Jacob, Sardar Sindhu, Amal Hasan, Md. Zubbair Malik, Hossein Arefanian, Fatema Al-Rashed, Rasheeba Nizam, Shihab Kochumon, Reeby Thomas, Fatemah Bahman, Steve Shenouda, Ajit Wilson, Nadeem Akther, Areej Al-Roub, Nermeen Abukhalaf, Shaima Albeloushi, Mohamed Abu-Farha, Ashraf Al Madhoun, Fawaz Alzaid, Thangavel Alphonse Thanaraj, Heikki A. Koistinen, Jaakko Tuomilehto, Fahd Al-Mulla, Rasheed Ahmad
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
High-fat diets (HFDs) shape the gut microbiome and promote obesity, inflammation, and liver steatosis. Fish and soybean are part of a healthy diet; however, the impact of these fats, in the absence of sucrose, on gut microbial dysbiosis and its assoc
Externí odkaz:
https://doaj.org/article/d3ab3726b78f47ddbc7105c15171b775
Autor:
Halemah AlSaeed, Mohammed J.A. Haider, Fawaz Alzaid, Fahd Al-Mulla, Rasheed Ahmad, Fatema Al-Rashed
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110046- (2024)
Summary: The interplay between lipid metabolism and immune response in macrophages plays a pivotal role in various infectious diseases, notably tuberculosis (TB). Herein, we illuminate the modulatory effect of heat-killed Mycobacterium tuberculosis (
Externí odkaz:
https://doaj.org/article/42916db84a284e6e99ab3f7ca7c1906d
Autor:
Areej Al-Roub, Nadeem Akhter, Fatema Al-Rashed, Ajit Wilson, Fawaz Alzaid, Fahd Al-Mulla, Sardar Sindhu, Rasheed Ahmad
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Studies have established the association between increased plasma levels of matrix metalloproteinase (MMP)-9 and adipose tissue inflammation. Tumor necrosis factor α (TNFα) was elevated in obesity and is involved in the induction of MMP-9
Externí odkaz:
https://doaj.org/article/cab7c9321ac24467a468e8a379a7e3d9
Autor:
Fatemah Bahman, Halemah AlSaeed, Shaima Albeloushi, Fahd Al-Mulla, Rasheed Ahmad, Fatema Al-Rashed
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Toll-like receptors (TLRs) have been targeted for therapeutic drug development for several disorders, including cardiovascular diseases (CVD), and diabetes mellitus. Daily levels physical activity (PA) has been purported to influence the sys
Externí odkaz:
https://doaj.org/article/c3be322cec3e434e93fbf0dcda688ce8
Autor:
Shaima Albeloushi, Amal Hasan, Hossein Arefanian, Sardar Sindhu, Fatema Al-Rashed, Shihab Kochumon, Nermeen Abukhalaf, Texy Jacob, Steve Shenouda, Ashraf Al Madhoun, Fahd Al-Mulla, Rasheed Ahmad
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionA high-fat/high-sucrose diet leads to adverse metabolic changes that affect insulin sensitivity, function, and secretion. The source of fat in the diet might inhibit or increase this adverse effect. Fish oil and cocoa butter are a signifi
Externí odkaz:
https://doaj.org/article/7f23b46502ab4244b0212a071e320f34
Autor:
Hossein Arefanian, Ashraf Al Madhoun, Fatema Al-Rashed, Fawaz Alzaid, Fatemah Bahman, Rasheeba Nizam, Mohammed Alhusayan, Sumi John, Sindhu Jacob, Michayla R. Williams, Nermeen Abukhalaf, Steve Shenouda, Shibu Joseph, Halemah AlSaeed, Shihab Kochumon, Anwar Mohammad, Lubaina Koti, Sardar Sindhu, Mohamed Abu-Farha, Jehad Abubaker, Thangavel Alphonse Thanaraj, Rasheed Ahmad, Fahd Al-Mulla
Publikováno v:
Cells, Vol 13, Iss 11, p 949 (2024)
This study unveils verapamil’s compelling cytoprotective and proliferative effects on pancreatic β-cells amidst diabetic stressors, spotlighting its unforeseen role in augmenting cholecystokinin (CCK) expression. Through rigorous investigations em
Externí odkaz:
https://doaj.org/article/d5c54f4e6884425089959cb62cb3ac2c
Autor:
Muhammad Sajid Hamid Akash, Azka Yaqoob, Kanwal Rehman, Muhammad Imran, Mohammed A. Assiri, Fatema Al-Rashed, Fahd Al-Mulla, Rasheed Ahmad, Sardar Sindhu
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Heavy metals are the metal compounds found in earth’s crust and have densities higher than that of water. Common heavy metals include the lead, arsenic, mercury, cadmium, copper, manganese, chromium, nickel, and aluminum. Their environmental levels
Externí odkaz:
https://doaj.org/article/4b90f70d640a498a96a7f9bd06474d01
Autor:
Fatema Al-Rashed, Dania Haddad, Ashraf Al Madhoun, Sardar Sindhu, Texy Jacob, Shihab Kochumon, Lina M. Obeid, Fahd Al-Mulla, Yusuf A. Hannun, Rasheed Ahmad
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107145- (2023)
Summary: Foamy and inflammatory macrophages play pathogenic roles in metabolic disorders. However, the mechanisms that promote foamy and inflammatory macrophage phenotypes under acute-high-fat feeding (AHFF) remain elusive. Herein, we investigated th
Externí odkaz:
https://doaj.org/article/0750756213684db996e41c9dcbf57676