Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Fatema, Hersi"'
Publikováno v:
Life Sciences. 320:121541
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c3ca39ed615167127488c2eb0f23b33
https://doi.org/10.1016/j.lfs.2023.121541
https://doi.org/10.1016/j.lfs.2023.121541
Autor:
Fatema Hersi, Wafaa R. Mohamed, Amira M. Abo-Youssef, Osama M. Ahmed, Gaber F Ali, Hany A. Omar
Publikováno v:
Current Molecular Pharmacology. 15:252-262
Background: Liver cancer ranks as the 7th and 5th leading cause of cancer morbidity worldwide in men and women, respectively. Hepatocellular Carcinoma (HCC) is the most common type of liver cancer and is associated with an increasing global burden of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784993b8497e6be2cecb4c7b5fa3ab0e
https://doi.org/10.2174/1874467214666210708103752
https://doi.org/10.2174/1874467214666210708103752
Autor:
Dana Zaher, Wafaa Ramadan, Raafat El-Awady, Hany Omar, Fatema Hersi, Vunnam Srinivasulu, Ibrahim Hachim, Farah Al Marzooq, Cijo Vazhappilly, Salim Merali, Carmen Merali, Nelson Soars, Paul Schilf, Saleh Ibrahim, Taleb AlTel
Background and Purpose: The dual inhibition of thioredoxin reductase (TrxR) and glutathione reductase (GSHR) has emerged as a promising approach for the treatment of cancer and for promoting the defense mechanism by the immune system. In a previous r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::617daa8e6ce3649b9d2afa2c2cca27dd
https://doi.org/10.22541/au.164865011.11779382/v1
https://doi.org/10.22541/au.164865011.11779382/v1
Publikováno v:
Life Sciences. 304:120699
The contribution of autophagy to drug resistance has been studied in several cancers. However, there is no clear evidence about the role of autophagy in the resistance to chemotherapy in cancers, such as hepatocellular carcinoma (HCC). HCC is charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4727465916917d2c03f5dfe9f1665b
https://doi.org/10.1016/j.lfs.2022.120699
https://doi.org/10.1016/j.lfs.2022.120699
Autor:
Hany A. Omar, Salim Merali, Cijo George Vazhappilly, Paul Schilf, Vunnam Srinivasulu, Wafaa S. Ramadan, Raafat El-Awady, Saleh M. Ibrahim, Dana M. Zaher, Nelson C. Soares, Fatema Hersi, Carmen Merali, Ibrahim Y. Hachim, Taleb H. Al-Tel, Farah Al-Marzooq
Publikováno v:
Cancers
Volume 13
Issue 11
Cancers, Vol 13, Iss 2840, p 2840 (2021)
Volume 13
Issue 11
Cancers, Vol 13, Iss 2840, p 2840 (2021)
Simple Summary This work aimed to illustrate the anticancer mechanism of action of a novel benzopyrane derivative as a potential anticancer lead compound. The anticancer activity of SIMR1281 against a panel of cancer cell lines was characterized. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a1fc10418c6808b5f6fa8c0b58f494
Autor:
Fatema, Hersi, Sara M, Elgendy, Salma A, Al Shamma, Roa T, Altell, Omar, Sadiek, Hany A, Omar
Publikováno v:
Life Sciences. 300:120573
The landscape of cancer therapy has undergone dramatic changes over the past decade. Immune checkpoint inhibitors (ICIs) among various cancer immunotherapies have transformed the treatment paradigm for cancer therapy and improved the survival of pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8842035d3ebf20b099681728116bb9
https://doi.org/10.1016/j.lfs.2022.120573
https://doi.org/10.1016/j.lfs.2022.120573
Autor:
Hany A. Omar, Fatema Hersi, Areej M. Jaber, Raed A. Al-Qawasmeh, Dana M. Zaher, Taleb H. Al-Tel, Zainab Ahmad
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
The incidence of obesity-related diseases like diabetes, cardiovascular diseases, and different types of cancers shed light on the importance of dietary control as preventive and treatment measures. However, long-term dietary control is challenging t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aea14526364c48829fcaeb9d38a8180
https://doi.org/10.1038/s41598-020-59685-x
https://doi.org/10.1038/s41598-020-59685-x
Autor:
Amany A. Azouz, Fatema Hersi, Fares E.M. Ali, Asmaa Mohammed M. Hussein Elkelawy, Hany A. Omar
Publikováno v:
Life Sciences. 288:120154
Aims The calcineurin inhibitor tacrolimus is an effective and widely used immunosuppressant after organ transplantation to reduce graft rejection. However, its nephrotoxic effect could compel the patients to treatment discontinuation. The beneficial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daecbcb84e53f389939b0dd3c23ca3c9
https://doi.org/10.1016/j.lfs.2021.120154
https://doi.org/10.1016/j.lfs.2021.120154
Autor:
Hajjaj H.M. Abdu-Allah, Hany A. Omar, Mohamed El-Naggar, Hamadeh Tarazi, Fatema Hersi, Sachin Chaudhary, Abdel-Nasser El-Shorbagi
Publikováno v:
Medicinal Chemistry Research. 27:1103-1110
In the search for promising anti-proliferative agents that might be helpful in the treatment of cancer effectively, several compounds in a series (4b–j) comprising 1,4-bis (5-substituted -2-thiono-2H-tetrahydro-1,3,5-thiadiazin-3-yl) butane derivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2be9b944e6dc0df6e4ccd3133e9a3a3
https://doi.org/10.1007/s00044-018-2133-9
https://doi.org/10.1007/s00044-018-2133-9
Autor:
Raafat El-Awady, Hany A. Omar, Vunnam Srinivasulu, Wafaa S. Ramadan, Taleb H. Al-Tel, Dana M. Zaher, Fatema Hersi
Publikováno v:
Cancer Research. 81:1244-1244
Introduction: Cancer is a leading cause of death worldwide, as about 1 in 6 deaths is due to cancer. Despite the advances in cancer treatment, the success rate of cancer cure is very low, due to the low therapeutic index and many off target side effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a000fd48098e9a2272e880570ddf9833
https://doi.org/10.1158/1538-7445.am2021-1244
https://doi.org/10.1158/1538-7445.am2021-1244