Engineering Clostridium organisms as microbial cell-factories: challenges & opportunities.

Autor: Charubin K; Department of Chemical and Biomolecular Engineering, University of Delaware, 150 Academy St., Newark, DE 19716, USA; The Delaware Biotechnology Institute, Molecular Biotechnology Laboratory, University of Delaware, 15 Innovation Way, Newark, DE 19711, USA. Electronic address: kamilcha@udel.edu., Bennett RK; Department of Chemical and Biomolecular Engineering, University of Delaware, 150 Academy St., Newark, DE 19716, USA; The Delaware Biotechnology Institute, Molecular Biotechnology Laboratory, University of Delaware, 15 Innovation Way, Newark, DE 19711, USA. Electronic address: rkbenne@udel.edu., Fast AG; Department of Chemical and Biomolecular Engineering, University of Delaware, 150 Academy St., Newark, DE 19716, USA; The Delaware Biotechnology Institute, Molecular Biotechnology Laboratory, University of Delaware, 15 Innovation Way, Newark, DE 19711, USA. Electronic address: alanfast@udel.edu., Papoutsakis ET; Department of Chemical and Biomolecular Engineering, University of Delaware, 150 Academy St., Newark, DE 19716, USA; The Delaware Biotechnology Institute, Molecular Biotechnology Laboratory, University of Delaware, 15 Innovation Way, Newark, DE 19711, USA. Electronic address: epaps@udel.edu.

Publikováno v: Metabolic engineering [Metab Eng] 2018 Nov; Vol. 50, pp. 173-191. Date of Electronic Publication: 2018 Jul 25.

Functional Expression of the Clostridium ljungdahlii Acetyl-Coenzyme A Synthase in Clostridium acetobutylicum as Demonstrated by a Novel In Vivo CO Exchange Activity En Route to Heterologous Installation of a Functional Wood-Ljungdahl Pathway.

Autor: Fast AG; Department of Chemical and Biomolecular Engineering and Delaware Biotechnology Institute, University of Delaware, Newark, Delaware, USA., Papoutsakis ET; Department of Chemical and Biomolecular Engineering and Delaware Biotechnology Institute, University of Delaware, Newark, Delaware, USA papoutsakis@dbi.udel.edu.

Publikováno v: Applied and environmental microbiology [Appl Environ Microbiol] 2018 Mar 19; Vol. 84 (7). Date of Electronic Publication: 2018 Mar 19 (Print Publication: 2018).

Acetogenic mixotrophy: novel options for yield improvement in biofuels and biochemicals production.

Autor: Fast AG; Molecular Biotechnology Laboratory, Department of Chemical & Biomolecular Engineering, & the Delaware Biotechnology Institute, University of Delaware, Newark, DE 19711, USA., Schmidt ED; Molecular Biotechnology Laboratory, Department of Chemical & Biomolecular Engineering, & the Delaware Biotechnology Institute, University of Delaware, Newark, DE 19711, USA., Jones SW; Elcriton, Inc., 15 Reads Way, New Castle, DE 19720, USA., Tracy BP; Elcriton, Inc., 15 Reads Way, New Castle, DE 19720, USA. Electronic address: bryantracy@elcriton.com.

Publikováno v: Current opinion in biotechnology [Curr Opin Biotechnol] 2015 Jun; Vol. 33, pp. 60-72. Date of Electronic Publication: 2014 Dec 10.

Overexpression of fetA (ybbL) and fetB (ybbM), Encoding an Iron Exporter, Enhances Resistance to Oxidative Stress in Escherichia coli.

Autor: Nicolaou SA; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA., Fast AG, Nakamaru-Ogiso E, Papoutsakis ET

Publikováno v: Applied and environmental microbiology [Appl Environ Microbiol] 2013 Dec; Vol. 79 (23), pp. 7210-9. Date of Electronic Publication: 2013 Sep 13.

Novel system for efficient isolation of Clostridium double-crossover allelic exchange mutants enabling markerless chromosomal gene deletions and DNA integration.

Autor: Al-Hinai MA; Department of Biological Sciences, University of Delaware, Newark, Delaware, USA., Fast AG, Papoutsakis ET

Publikováno v: Applied and environmental microbiology [Appl Environ Microbiol] 2012 Nov; Vol. 78 (22), pp. 8112-21. Date of Electronic Publication: 2012 Sep 14.