Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Fasih M. Ahsan"'
Publikováno v:
iScience, Vol 5, Iss , Pp 99-109 (2018)
Summary: B lymphocytes provide adaptive immunity by generating antigen-specific antibodies and supporting the activation of T cells. Little is known about how global metabolism supports naive B cell activation to enable an effective immune response.
Externí odkaz:
https://doaj.org/article/558153aa07ac42aba37a7a0d62887f41
Autor:
Lucydalila Cedillo, Fasih M Ahsan, Sainan Li, Nicole L Stuhr, Yifei Zhou, Yuyao Zhang, Adebanjo Adedoja, Luke M Murphy, Armen Yerevanian, Sinclair Emans, Khoi Dao, Zhaozhi Li, Nicholas D Peterson, Jeramie Watrous, Mohit Jain, Sudeshna Das, Read Pukkila-Worley, Sean P Curran, Alexander A Soukas
Publikováno v:
eLife, Vol 12 (2023)
Biguanides, including the world’s most prescribed drug for type 2 diabetes, metformin, not only lower blood sugar, but also promote longevity in preclinical models. Epidemiologic studies in humans parallel these findings, indicating favorable effec
Externí odkaz:
https://doaj.org/article/5f9402d37613409b85d1992e1eaa7bee
Autor:
Sinclair W. Emans, Armen Yerevanian, Fasih M. Ahsan, Yifei Zhou, Lucydalila Cedillo, Alexander A. Soukas
Both Hedgehog (Hh) signaling and target of rapamycin complex 2 (TORC2) are central, evolutionarily conserved pathways that regulate development and metabolism. InC. elegans, loss of essential TORC2 component RICTOR (rict-1) causes delayed development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aadda13848dce5c8ab82fa5dcf37fe5
https://doi.org/10.1101/2022.11.17.517002
https://doi.org/10.1101/2022.11.17.517002
Autor:
Armen Yerevanian, Luke M. Murphy, Sinclair Emans, Yifei Zhou, Fasih M. Ahsan, Daniel Baker, Sainan Li, Adebanjo Adedoja, Lucydalila Cedillo, Nicole L. Stuhr, Einstein Gnanatheepam, Khoi Dao, Mohit Jain, Sean P. Curran, Irene Georgakoudi, Alexander A. Soukas
Publikováno v:
Aging cell. 21(11)
Riboflavin is an essential cofactor in many enzymatic processes and in the production of flavin adenine dinucleotide (FAD). Here, we report that the partial depletion of riboflavin through knockdown of the C. elegans riboflavin transporter 1 (rft-1)
Autor:
Jeramie D. Watrous, Khoi Dao, Zhaozhi Li, Sudeshna Das, Read Pukkila-Worley, Sinclair Emans, Alexander A. Soukas, Fasih M. Ahsan, Nicholas D. Peterson, Adebanjo Adedoja, Sainan Li, Lucydalila Cedillo, Mohit Jain
Biguanides, including the world’s most commonly prescribed drug for type 2 diabetes, metformin, not only lower blood sugar, but also promote longevity in preclinical models. Epidemiologic studies in humans parallel these findings, indicating favora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::becd3043c6465d678e82982c5f657b4d
https://doi.org/10.1101/2021.09.02.457410
https://doi.org/10.1101/2021.09.02.457410
Autor:
Thomas G. Graeber, Diane N. H. Kim, Jason S. Hong, Fasih M. Ahsan, Michael A. Teitell, Johanna ten Hoeve, Daniel Braas, Lynnea R. Waters, Aspram Minasyan, Thomas A. Zangle
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific reports, vol 9, iss 1
Scientific Reports
Scientific reports, vol 9, iss 1
Scientific Reports
Ampk is an energy gatekeeper that responds to decreases in ATP by inhibiting energy-consuming anabolic processes and promoting energy-generating catabolic processes. Recently, we showed that Lkb1, an understudied kinase in B lymphocytes and a major u
Autor:
Peter D. Pioli, Encarnacion Montecino-Rodriguez, Justin Golovato, Nguyen Tl, Kenneth Dorshkind, Jason S. Hong, Fasih M. Ahsan, Martin Lee, Michael A. Teitell, Brooks Dg, Kayvan Niazi
Antibody secreting cell (ASC) function and longevity determines the strength and durability of a humoral immune response. Previously, we identified the inactivation of the CREB-regulated transcriptional coactivator-2 (CRTC2) in an in vitro B cell dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6131a211e7c6b36277cbbe2bf37dcdb1
https://doi.org/10.1101/2021.04.14.439620
https://doi.org/10.1101/2021.04.14.439620
Autor:
Thang L. Nguyen, Sixto Marcos, Pei-Yu Chiou, Shahrooz Rabizadeh, Alexander N. Patananan, Adam Lazar, Jon T. Van Lew, Noe Rodriguez, Luis Cisneros, Peter A. Sieling, Daniel Braas, Fasih M. Ahsan, Charles J. Vaske, Michael A. Teitell, Amy R. Vandiver, Amanda J. Collier, Artin Mehrabi, Alexander J. Sercel, Stephanie A.L. Kennedy, Lise Zakin, Emma R. Dawson, Tadros Wael, Alejandro Torres, Kayvan Niazi, Ting-Hsiang Wu, Justin Golovato, Kathrin Plath
Publikováno v:
Cell reports, vol 33, iss 13
Cell reports
Cell reports
SUMMARY Generating mammalian cells with desired mitochondrial DNA (mtDNA) sequences is enabling for studies of mitochondria, disease modeling, and potential regenerative therapies. MitoPunch, a high-throughput mitochondrial transfer device, produces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be74657fb561a48381afb40523ea40b
https://escholarship.org/uc/item/9xs7544n
https://escholarship.org/uc/item/9xs7544n
Publikováno v:
iScience, Vol 5, Iss, Pp 99-109 (2018)
Summary: B lymphocytes provide adaptive immunity by generating antigen-specific antibodies and supporting the activation of T cells. Little is known about how global metabolism supports naive B cell activation to enable an effective immune response.
Autor:
Fasih M. Ahsan, Alejandro Torres, Dian Huang, Alexander N. Patananan, Vivian Lu, Daniel Braas, Perrine Dahan, Irena J. Roy, Michael A. Teitell, Robert M. T. Nguyen
Publikováno v:
Cell Res