Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Fascione, Martin Anthony"'
During their lifetime almost half of women will experience a symptomatic urinary tract infection (UTI) with a further half experiencing a relapse within six months. Currently UTIs are treated with antibiotics, but increasing antibiotic resistance rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::d3efb3295ec6d9f972a742c8ff0f3785
https://eprints.whiterose.ac.uk/165058/1/manuscript_FimH_Accepted_article_.pdf
https://eprints.whiterose.ac.uk/165058/1/manuscript_FimH_Accepted_article_.pdf
Autor:
Valverde, Pablo, Vendeville, Jean-Baptiste, Hollingsworth, Kristian, Mattey, Ashley Philip, Keenan, Tessa, Chidwick, Harriet, Ledru, Helene, Huonnic, Kler, Light, Mark E., Turner, Nicholas, Jimenez Barbero, Jesus, Galan, M. Carmen, Fascione, Martin Anthony, Flitsch, Sabine, Turnbull, W. Bruce, Linclau, Bruno
Publikováno v:
Chem. Commun.
The first synthesis of 3-deoxy-3-fluoro-l-fucose is presented, which employs a d- to l-sugar translation strategy, and involves an enzymatic oxidation of 3-deoxy-3-fluoro-l-fucitol. Enzymatic activation (FKP) and glycosylation using an -1,2 and an -1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::b2ddb705352c0e46a2524bfb167e5a40
https://eprints.whiterose.ac.uk/160069/1/d0cc02209h.pdf
https://eprints.whiterose.ac.uk/160069/1/d0cc02209h.pdf
The non-mammalian nonulosonic acid sugar pseudaminic acid (Pse) is present on the surface of a number of human pathogens including Campylobacter jejuni and Helicobacter pylori and other bacteria such as multidrug resistant Acinetobacter baumannii. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::640745862026f19f224dc7468fbf1f51
https://eprints.whiterose.ac.uk/159297/1/Pse_review_09.12.19_full.pdf
https://eprints.whiterose.ac.uk/159297/1/Pse_review_09.12.19_full.pdf
Autor:
Yates, Nick, Dowsett, Mark, Bentley, Phillip, Dickenson-Fogg, Jack, Pratt, Andrew, Blanford, Christopher, Fascione, Martin Anthony, Parkin, Alison
We report a diazonium electro-grafting method for the covalent modification of conducting surfaces with aldehyde-reactive hydroxylamine functionalities that facilitate the wiring of redox-active (bio)molecules to electrode surfaces. Hydroxylamine mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::34d0adcaff81236b3381f6e47cd0a6c6
https://eprints.whiterose.ac.uk/156673/1/acs.langmuir.9b01254.pdf
https://eprints.whiterose.ac.uk/156673/1/acs.langmuir.9b01254.pdf
Autor:
Yates, Nicholas David James, Brabham, Robin Louis, Spears, Richard James, Keenan, Tessa, Helliwell, Philip A., Pugh, David Stephen, Parkin, Alison, Hurst, Glenn A., Fascione, Martin Anthony
A laboratory experiment introducing the concept of chemical bioconjugation of proteins to undergraduate students in a therapeutically relevant context was developed. Initially, students installed an aldehyde functionality into a protein via the oxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::d1cd7b37ca6d1fbd187aedb2eec07af1
https://eprints.whiterose.ac.uk/144547/1/Chem_Educ_subm_manuscript_revised_non_highlighted.pdf
https://eprints.whiterose.ac.uk/144547/1/Chem_Educ_subm_manuscript_revised_non_highlighted.pdf
Autor:
Budhadev, Darshita, Saxby, Karinna, Walton, Julia, Davies, Gideon John, Tyler, Peter, Schworer, Ralf, Fascione, Martin Anthony
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::e6c3f9f2b26cc05c2b91dbe51395323d
https://eprints.whiterose.ac.uk/139888/1/accepted_articel_for_deposition.pdf
https://eprints.whiterose.ac.uk/139888/1/accepted_articel_for_deposition.pdf
The immobilization of redox proteins or enzymes onto conductive surfaces has application in the analysis of biological processes, the fabrication of biosensors, and in the development of green technologies and biochemical synthetic approaches. This r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::dd741d3766fdc7333e6cadb825a9f2a1
https://eprints.whiterose.ac.uk/133809/1/Yates_et_al_2018_Chemistry_A_European_Journal.pdf
https://eprints.whiterose.ac.uk/133809/1/Yates_et_al_2018_Chemistry_A_European_Journal.pdf
The incorporation of aldehyde handles into proteins, and subsequent chemical reactions thereof, is rapidly proving to be an effective way of generating homogeneous, covalently linked protein constructs that can display a vast array of functionality.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::cce806913759b1255cffee1d944ba343
https://eprints.whiterose.ac.uk/105157/1/c6ob00778c.pdf
https://eprints.whiterose.ac.uk/105157/1/c6ob00778c.pdf