Zobrazeno 1 - 10
of 20
pro vyhledávání: '"FasL, Fas ligand"'
Autor:
Kambez H. Benam, Brian F. Niemeyer
Publikováno v:
Pharmacology & Therapeutics
Responding quickly to emerging respiratory viruses, such as SARS-CoV-2 the causative agent of coronavirus disease 2019 (COVID-19) pandemic, is essential to stop uncontrolled spread of these pathogens and mitigate their socio-economic impact globally.
Autor:
Sjoerd J L van Wijk, Simone Fulda, Birte Jeiler, Jens Roedig, Nadezda Dolgikh, Annkathrin Koch
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 5, Pp 539-550 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 5, Pp 539-550 (2021)
Burkitt's lymphoma (BL) is a highly aggressive form of B-cell non-Hodgkin's lymphoma. The clinical outcome in children with BL has improved over the last years but the prognosis for adults is still poor, highlighting the need for novel treatment stra
Autor:
Eleonora Distrutti, Cristina Di Giorgio, Oxana Bereshchenko, Margherita Magro, Michele Biagioli, Stefano Fiorucci, Rosalinda Roselli, Paolo Scarpelli, Angela Zampella, Silvia Marchianò, Adriana Carino, Chiara Fiorucci
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 3, Pp 447-473 (2019)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims GPBAR1, also known as TGR5, is a G protein–coupled receptor activated by bile acids. Hepatic innate immune cells are involved in the immunopathogenesis of human liver diseases and in several murine hepatitis models. Here, by using
Autor:
Atieh Pourbagheri-Sigaroodi, Naeimeh Tavakolinia, Nader Bagheri, Mahda Delshad, Davood Bashash, Ava Safaroghli-Azar
Publikováno v:
International Immunopharmacology
Graphical abstract
The incidence of the novel coronavirus disease (COVID-19) outbreak caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought daunting complications for people as well as physicians around the world
The incidence of the novel coronavirus disease (COVID-19) outbreak caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought daunting complications for people as well as physicians around the world
Publikováno v:
Clinical Science (London, England : 1979)
Pigment epithelium-derived factor (PEDF) is a broadly expressed multifunctional member of the serine proteinase inhibitor (serpin) family. This widely studied protein plays critical roles in many physiological and pathophysiological processes, includ
Publikováno v:
Seminars in Cancer Biology
The FOXO3 and FOXM1 forkhead box transcription factors, functioning downstream of the essential PI3K-Akt, Ras-ERK and JNK/p38MAPK signalling cascades, are crucial for cell proliferation, differentiation, cell survival, senescence, DNA damage repair a
Autor:
Jon Hazeldine, Janet M. Lord
Publikováno v:
Ageing Research Reviews
Highlights • Roles are emerging for natural killer (NK) cells beyond removing transformed cells. • These include immune regulation and the elimination of senescent cells. • Human ageing is associated with a decline in NK cell function. • We p
Autor:
Hedger, M.P.
Publikováno v:
Comprehensive Toxicology
A large body of evidence points to the existence of a close, dynamic relationship between the immune system and the male reproductive tract, which has important implications for our understanding of both systems. The testis and the male reproductive
Publikováno v:
Redox Biology
Photodynamic therapy (PDT) against cancer has gained attention due to the successful outcome in some cancers, particularly those on the skin. However, there have been limitations to PDT applications in deep cancers and, occasionally, PDT treatment re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a2a85eacc8fcbea6efea6778c8ccbb
https://escholarship.org/uc/item/5t4270wx
https://escholarship.org/uc/item/5t4270wx
Publikováno v:
Current Opinion in Immunology
CD8 + T-cell memory to viruses is stable in the absence but volatile in the presence of other infections. Apoptotic events that occur early in acute infections delete pre-existing memory T cells, leaving the host with reduced memory (except for cross