Uncertain Identity of Doxorubicin-Resistant MCF-7 Cell Lines Expressing Mutated p53

Autor: Andreas Marti, Farzaneh Pirnia, Michel A. Hotz, Markus Borner, Madlaina Breuleux, Manfred Hochmeister, Susan E. Bates, Erasmus Schneider, Daniel Betticher

Publikováno v: Pirnia, Farzaneh; Breuleux, Madlaina; Schneider, Erasmus; Hochmeister, Manfred; Bates, Susan E.; Marti, Andreas; Hotz, Michel A.; Betticher, Daniel C.; Borner, Markus M. (2000). Uncertain Identity of Doxorubicin-Resistant MCF-7 Cell Lines Expressing Mutated p53. Journal of the National Cancer Institute JNCI, 92(18), pp. 1535-1536. Oxford University Press 10.1093/jnci/92.18.1535

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31191ab2f043f54c29a5646201336d80
http://doc.rero.ch/record/289229/files/0921535.pdf

Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint

Autor: Mikhail V. Blagosklonny, Benjamin Knepper, Jane B. Trepel, J. Frederic Mushinski, Olaf Schaefer, Farzaneh Pirnia, Maria Tsokos, Jung Sik Kim, Yung Hyun Choi, Michael J. Birrer, Phuong Mai Nguyen, Theodor W. Schulte

Publikováno v: Oncogene. 19:6082-6090

To develop a new approach to the treatment of primitive neuroectodermal tumors we evaluated the effect of the HMG-CoA reductase inhibitor lovastatin on the Ewing's sarcoma cell line CHP-100. Lovastatin induced neural morphology and markers including

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed6c12e53a09c27ba43c772fdbb0418
https://doi.org/10.1038/sj.onc.1204008

The detergent Triton X-100 induces a death pattern in human carcinoma cell lines that resembles cytotoxic lymphocyte-induced apoptosis

Autor: Erasmus Schneider, Jane B. Trepel, Markus Borner, Charles E. Myers, Farzaneh Pirnia, Oliver Sartor

Publikováno v: FEBS Letters. 353:129-132

The detergent Triton X-100 (TX100) was used with the intention to establish a model for necrotic cell death. However TX100 was found to induce apoptotic and necrotic death in prostate and colon cancer cell lines. Apoptosis was characterized by the ty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc794556f5e0f96378fc59eef5809fa
https://doi.org/10.1016/0014-5793(94)01023-4

Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns

Autor: Markus M. Borner, A. Tobler, Mario P. Tschan, Martin F. Fey, Kimberlee M. Fischer, Vivian S. Fung, Farzaneh Pirnia, Bruce E. Torbett

Publikováno v: The Journal of biological chemistry. 278(44)

We have cloned two novel, alternatively spliced messages of human cyclin D-binding Myb-like protein (hDMP1). The known, full-length protein has been named hDMP1alpha and the new isoforms, hDMP1beta and hDMP1gamma. The hDMP1alpha, -beta, and -gamma sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec37e7479d4810f4456fb6969b1787ed
https://pubmed.ncbi.nlm.nih.gov/12917399

Cytotoxicity and metabolism of 4-methoxy-8-(beta-D-ribofuranosylamino)pyrimido[5,4-d]pyrimidine in HCT 116 colon cancer cells

Autor: Jean L. Grem, Pamela Daychild, Jane B. Trepel, James C. Drake, F. Geoffroy, Farzaneh Pirnia, Carmen J. Allegra

Publikováno v: Biochemical pharmacology. 48(11)

We examined the cytotoxicity, biochemical effects and metabolism of 4-methoxy-8-(beta-D-ribofuranosylamino)pyrimido[5,4-d]pyrimidine (MRPP), a synthetic nucleoside inhibitor of phosphoribosylpyrophosphate synthetase, in HCT 116 human colorectal cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c9d780a425394a2b0b991d12442207
https://pubmed.ncbi.nlm.nih.gov/7528507