Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Farzaneh Mohamadi Farsani"'
Publikováno v:
Cell Journal, Vol 25, Iss 12, Pp 874-882 (2023)
Objective: Wound healing is a complex process involving the coordinated interaction of various genes and molecularpathways. The study aimed to uncover novel therapeutic targets, biomarkers and candidate genes for drug developmentto improve successful
Externí odkaz:
https://doaj.org/article/e259ef2953ff45a6959226f4169f2222
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The pathways and robust deregulated gene signatures involved in AML chemo-resistance are not fully understood. Multiple subgroups of AMLs which are under treatment of various regimens seem to have similar regulatory gene(s) or pathway(s) rel
Externí odkaz:
https://doaj.org/article/a59b6b2f338847b0a12172c886070653
Publikováno v:
مجله انفورماتیک سلامت و زیست پزشکی, Vol 3, Iss 4, Pp 310-318 (2017)
Introduction: The majority of drugs act through binding with target proteins. Prediction of the interaction between small molecules and proteins is a key element in the process of drug discovery. Advances in Structural Genomics have provided this pos
Externí odkaz:
https://doaj.org/article/bb871f63942948209a885df4d1c8eb41
Publikováno v:
RSC Advances. 11:11048-11056
Protein kinases play a significant role in cellular activation procedures by exhibiting a vivid selection in the target, as well as recognizing and phosphorylating them. Extracellular signal-regulated kinase 2 (ERK2) is one of the main kinases in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c741ac560a0d454cf15a0e7d7fd671bd
https://doi.org/10.1039/d1ra01020d
https://doi.org/10.1039/d1ra01020d
Publikováno v:
RSC advances. 11(19)
Protein kinases play a significant role in cellular activation procedures by exhibiting a vivid selection in the target, as well as recognizing and phosphorylating them. Extracellular signal-regulated kinase 2 (ERK2) is one of the main kinases in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e79f47d967e08c887171b0ff13c8fb48
https://pubmed.ncbi.nlm.nih.gov/35423626
https://pubmed.ncbi.nlm.nih.gov/35423626
Autor:
Farzaneh Mohamadi Farsani, Mohamad Reza Ganjalikhany, Noushin Hadian, Mehdi Sadeghi, Hossein Sazegar
Publikováno v:
Critical Reviews in Eukaryotic Gene Expression. 29:177-187
The vast majority of drugs act through binding to their protein targets. Prediction of the interaction between small molecules and these receptors is a key element in the process of drug discovery. Advances in structural biology have enabled us to re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d517772d7f2fe812421e0e4a965e1e
https://doi.org/10.1615/critreveukaryotgeneexpr.2019026432
https://doi.org/10.1615/critreveukaryotgeneexpr.2019026432
Publikováno v:
International Journal of Cancer Management.
Background: DNA topoisomerase II alpha (Top2-α) enzyme is an important target for many anticancer drugs. A variety of TOP2A genomic variants has been found associated with the development of drug resistance to this enzyme. Methods: Here, we have cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcd4e29c7a939f04be94a2643383ce39
https://doi.org/10.5812/ijcm.66993
https://doi.org/10.5812/ijcm.66993
Autor:
Mohamad Reza Ganjalikhany, Sadeq Vallian, Moein Dehbashi, Marjan Mojtabavi Naeini, Farzaneh Mohamadi Farsani
Publikováno v:
Medicinal Chemistry Research. 25:1250-1259
Topoisomerases are enzymes that resolve winding problem of DNA during cellular processes. Because of essential roles of these enzymes in maintenance of cell function, topoisomerases are important targets for cancer chemotherapy. To date, several topo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a44b17fa917d947db09caf20c5c7aae
https://doi.org/10.1007/s00044-016-1567-1
https://doi.org/10.1007/s00044-016-1567-1
Publikováno v:
Current Cancer Drug Targets. 17
Background DNA topoisomerase II-α (Top2-α), an essential enzyme for the management of DNA during replication, transcription, recombination, and chromatin remodeling, is one of the most important anticancer targets. Numerous molecules have been desi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5dfa738e5cb5c1b11e6d35581840c8
https://doi.org/10.2174/1568009617666161109142629
https://doi.org/10.2174/1568009617666161109142629
Publikováno v:
Asian Journal of Pharmaceutical and Clinical Research. 10:411
Objective: This study was aimed to investigate the association between polymorphisms in MTHFR gene and Vitamin B12-dependent homocysteine metabolism.Methods: Hyperhomocysteinemia has been implicated as a risk factor for complications in pregnancy inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f3bb32cceb232d763a123d9e0d11087
https://doi.org/10.22159/ajpcr.2017.v10i12.21579
https://doi.org/10.22159/ajpcr.2017.v10i12.21579