Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Faryal F. Mir"'
Autor:
Elisabeth H. Vollmann, Lizhi Cao, Aldo Amatucci, Taylor Reynolds, Stefan Hamann, Isin Dalkilic-Liddle, Thomas O. Cameron, Markus Hossbach, Kevin J. Kauffman, Faryal F. Mir, Daniel G. Anderson, Tatiana Novobrantseva, Victor Koteliansky, Tatiana Kisseleva, David Brenner, Jeremy Duffield, Linda C. Burkly
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 314-323 (2017)
Fibrotic diseases contribute to 45% of deaths in the industrialized world, and therefore a better understanding of the pathophysiological mechanisms underlying tissue fibrosis is sorely needed. We aimed to identify novel modifiers of tissue fibrosis
Externí odkaz:
https://doaj.org/article/0a07061608884d5ebedd059c50812d16
Autor:
Dorela D. Shuboni-Mulligan, Erik M. Shapiro, Ryan P. Tomaszewski, Nicholas Ether, Jeremy M. L. Hix, Faryal F. Mir, Christiane L. Mallett
Publikováno v:
Magn Reson Med
PURPOSE While rodents are the primary animal models for contrast agent evaluation, rodents can potentially misrepresent human organ clearance of newly developed contrast agents. For example, gadolinium (Gd)-BOPTA has ~50% hepatic clearance in rodents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11849acdedfe8f2258895293103b1370
https://doi.org/10.1002/mrm.27730
https://doi.org/10.1002/mrm.27730
Autor:
Asha K. Patel, Frank Derosa, Suman Bose, James C. Kaczmarek, Kevin J. Kauffman, Michael W. Heartlein, Robert Langer, Daniel G. Anderson, Faryal F. Mir
Publikováno v:
Adv Mater
Other repository
Other repository
Noninvasive aerosol inhalation is an established method of drug delivery to the lung, and remains a desirable route for nucleic-acid-based therapeutics. In vitro transcribed (IVT) mRNA has broad therapeutic applicability as it permits temporal and do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be9fe9c44fa31d29ea71dc0041a22d5
https://pubmed.ncbi.nlm.nih.gov/30609147
https://pubmed.ncbi.nlm.nih.gov/30609147
Autor:
Daniel G. Anderson, Taylor E. Shaw, James E. Dahlman, Yiping Xing, Robert Langer, Faryal F. Mir, Eric T. Wang, Chloe C. Dlott, Kevin J. Kauffman
Nucleic acid therapeutics are limited by inefficient delivery to target tissues and cells and by an incomplete understanding of how nanoparticle structure affects biodistribution to off-target organs. Although thousands of nanoparticle formulations h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8543cdcb87a622bffa92016f78e350a1
https://europepmc.org/articles/PMC5338412/
https://europepmc.org/articles/PMC5338412/
Autor:
Suman Bose, Asha K. Patel, James C. Kaczmarek, Daniel G. Anderson, Frank Derosa, Kevin J. Kauffman, Faryal F. Mir, Michael W. Heartlein, Robert Langer
Publikováno v:
Advanced Materials. 31:1970053
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d83a926faebf1826454556ce43cb56d7
https://doi.org/10.1002/adma.201970053
https://doi.org/10.1002/adma.201970053
Autor:
Tatiana Kisseleva, Isin Dalkilic-Liddle, David A. Brenner, Tatiana Novobrantseva, Taylor L. Reynolds, Jeremy S. Duffield, Daniel G. Anderson, Victor Koteliansky, Aldo Amatucci, Elisabeth H. Vollmann, Faryal F. Mir, Stefan Hamann, Lizhi Cao, Thomas Cameron, Markus Hossbach, Linda C. Burkly, Kevin J. Kauffman
Publikováno v:
Elsevier
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 314-323 (2017)
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 314-323 (2017)
Molecular Therapy. Nucleic Acids
Fibrotic diseases contribute to 45% of deaths in the industrialized world, and therefore a better understanding of the pathophysiological mechanisms underlying tissue fibrosis is sorely needed. We aimed to identify novel modifiers of tissue fibrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1f6bdfdf29c3e4fba79efadc80cbd0
https://hdl.handle.net/1721.1/121997
https://hdl.handle.net/1721.1/121997
Autor:
Kevin J. Kauffman, Michael W. Heartlein, Daniel G. Anderson, Matthew J. Webber, Piotr S. Kowalski, Juan E. Hurtado, Frank Derosa, Siddharth Jhunjhunwala, James C. Kaczmarek, Faryal F. Mir, Jung H. Yang
Publikováno v:
PMC
Biomaterials
Biomaterials
mRNA has broad potential for treating diseases requiring protein expression. However, mRNA can also induce an immune response with associated toxicity. Replacement of uridine bases with pseudouridine has been postulated to modulate both mRNA immunoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b4d19a6dc58fef82e7e3d70552777a
https://orcid.org/0000-0001-8046-2288
https://orcid.org/0000-0001-8046-2288
Autor:
Jung H. Yang, Owen S. Fenton, J. Robert Dorkin, Kevin J. Kauffman, Michael W. Heartlein, Frank Derosa, Faryal F. Mir, Daniel G. Anderson
Publikováno v:
Nano letters. 15(11)
Intracellular delivery of messenger RNA (mRNA) has the potential to induce protein production for many therapeutic applications. Although lipid nanoparticles have shown considerable promise for the delivery of small interfering RNAs (siRNA), their ut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd7b4d61d9cd2951d511a069645531c
https://pubmed.ncbi.nlm.nih.gov/26469188
https://pubmed.ncbi.nlm.nih.gov/26469188
Autor:
Rebecca L. McClellan, Jung H. Yang, Matthias A. Oberli, James C. Kaczmarek, Robert Langer, Owen S. Fenton, Mark W. Tibbitt, Michael W. Heartlein, Siddharth Jhunjhunwala, Frank Derosa, Manhao D. Zeng, Faryal F. Mir, Daniel G. Anderson, Kevin J. Kauffman, Eric A. Appel, Joseph R. Dorkin
Publikováno v:
Advanced Materials. 29:1606944
B lymphocytes regulate several aspects of immunity including antibody production, cytokine secretion, and T-cell activation; moreover, B cell misregulation is implicated in autoimmune disorders and cancers such as multiple sclerosis and non-Hodgkin's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f6d2da7a17d5228ea3f75a39ae0a26
https://doi.org/10.1002/adma.201606944
https://doi.org/10.1002/adma.201606944
Autor:
Kevin J. Kauffman, J. Robert Dorkin, Jung H. Yang, Michael W. Heartlein, Frank DeRosa, Faryal F. Mir, Owen S. Fenton, Daniel G. Anderson
Publikováno v:
Nano Letters; Nov2015, Vol. 15 Issue 11, p7300-7306, 7p