Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Farwah, Iqbal"'
Autor:
Farwah Iqbal, Alexander Johnston, Brandon Wyse, Razieh Rabani, Poonam Mander, Banafshe Hoseini, Jun Wu, Ren-Ke Li, Andrée Gauthier-Fisher, Peter Szaraz, Clifford Librach
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Cell-based therapeutics are promising interventions to repair ischemic cardiac tissue. However, no single cell type has yet been found to be both specialized and versatile enough to heal the heart. The synergistic effects of two regenerative
Externí odkaz:
https://doaj.org/article/5b8188ebabf84e22ae49025197c65b59
Autor:
Farwah Iqbal, Florian Schlotter, Dakota Becker-Greene, Adrien Lupieri, Claudia Goettsch, Joshua D Hutcheson, Maximillian A Rogers, Shinsuke Itoh, Arda Halu, Lang Ho Lee, Mark C Blaser, Andrew K Mlynarchik, Sumihiko Hagita, Shiori Kuraoka, Hao Yu Chen, James C Engert, Livia S A Passos, Prabhash K Jha, Eric A Osborn, Farouc A Jaffer, Simon C Body, Simon C Robson, George Thanassoulis, Masanori Aikawa, Sasha A Singh, Abhijeet R Sonawane, Elena Aikawa
Publikováno v:
European Heart Journal. 44:885-898
AimsCalcific aortic valve disease (CAVD) is the most common valve disease, which consists of a chronic interplay of inflammation, fibrosis, and calcification. In this study, sortilin (SORT1) was identified as a novel key player in the pathophysiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17619affe70613293bf816312001402b
https://doi.org/10.1093/eurheartj/ehac818
https://doi.org/10.1093/eurheartj/ehac818
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-14 (2017)
Abstract Background Due to limitations of current angiogenesis assays, we aimed to develop a novel application of the rat aortic ring assay to assess the angiogenic potential of mesenchymal stromal cells (MSCs). First-trimester human umbilical cord-d
Externí odkaz:
https://doaj.org/article/32530d86b9ae49adb3f8dbcb656f6228
Autor:
Peter Szaraz, Matthew Librach, Poonam Mander, Banafshe Hoseini, Max Librach, Farwah Iqbal, Clifford Librach
Publikováno v:
Biology Open, Vol 8, Iss 7 (2019)
High quality cell cultures require reliable laboratory practices. Today's small-scale in vitro cell culture format is dominated by circular topology vessels, with the inherent disadvantage of secondary flow induced each time the cell cultures are rep
Externí odkaz:
https://doaj.org/article/1800bc4a1aea49abb48ddbd1082c5b89
Autor:
Meghan W. Sedovy, Xinyan Leng, Melissa R. Leaf, Farwah Iqbal, Laura Beth Payne, John C. Chappell, Scott R. Johnstone
Connexin 43 (Cx43) is essential to the function of the vasculature. Cx43 proteins form gap junctions that allow for the exchange of ions and molecules between vascular cells to facilitate cell-to-cell signaling and coordinate vasomotor activity. Cx43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdf8f94185cc22c4e493b4a3b3c3150
https://hdl.handle.net/10919/112060
https://hdl.handle.net/10919/112060
Publikováno v:
Arterioscler Thromb Vasc Biol
The transition of healthy arteries and cardiac valves into dense, cell-rich, calcified, and fibrotic tissues is driven by a complex interplay of both cellular and molecular mechanisms. Specific cell types in these cardiovascular tissues become activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed5fe3a2c830d849a14a2031e6bcc01
https://doi.org/10.1161/atvbaha.120.314776
https://doi.org/10.1161/atvbaha.120.314776
Autor:
Peter Szaraz, Matthew Librach, Leila Maghen, Farwah Iqbal, Tanya A. Barretto, Shlomit Kenigsberg, Andrée Gauthier-Fisher, Clifford L. Librach
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Myocardial infarction (MI) causes an extensive loss of heart muscle cells and leads to congestive heart disease (CAD), the leading cause of mortality and morbidity worldwide. Mesenchymal stromal cell- (MSC-) based cell therapy is a promising option t
Externí odkaz:
https://doaj.org/article/3a8db5f1f4e64135960eb3487b175ae5
Publikováno v:
Angiogenesis. 23:131-144
Perivascular cells (PVC) and their "progeny," mesenchymal stromal cells (MSC), have high therapeutic potential for ischemic diseases. While hypoxia can increase their angiogenic properties, the other aspect of ischemic conditions-glucose shortage-is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033bb865408141ea390065ea96c9ae82
https://doi.org/10.1007/s10456-019-09682-0
https://doi.org/10.1007/s10456-019-09682-0
Publikováno v:
Contemporary Cardiology ISBN: 9783030467241
Osteoclasts are a specific subset of immune-derived, bone-resorbing cells. Because osteoclasts are the only cells that can resorb calcification, they act as crucial regulators of bone remodeling. Osteoclasts are large, multinucleated cells that fuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7d7ea7226b82eaf21020784484e1f66
https://doi.org/10.1007/978-3-030-46725-8_18
https://doi.org/10.1007/978-3-030-46725-8_18
Autor:
Jun Wu, P. Mander, Farwah Iqbal, Ren-Ke Li, Száraz Péter, Banafshe Hoseini, Clifford Librach, Alexandra Lucato, Alexander Johnston
Publikováno v:
Circulation Research. 125
Introduction: FTM HUCPVC are a novel source of young, immunoprivileged mesenchymal stromal cells (MSC). FTM HUCPVC demonstrate significant homing, angiogenic and tissue remodelling capacities in vitro . We aimed to explore the therapeutic potential o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cdc3935cbf6df01d7a61a77dd2b011a
https://doi.org/10.1161/res.125.suppl_1.717
https://doi.org/10.1161/res.125.suppl_1.717