Exploring the Antidiarrheal Properties of Papaya Leaf: Insights In Vivo Study in Mice-Model and In Silico Analysis at M3 Muscarinic Acetylcholine Receptor Interaction

Autor: Nyi Mekar Saptarini, Faruk Jayanto Kelutur, Mary Jho-Anne Tolentino Corpuz

Publikováno v: Scientifica, Vol 2024 (2024)

Diarrhea caused by gut motility involves 5-HT3 serotonin receptor (5-HT3R) antagonist, M3 muscarinic acetylcholine receptor (M3-AchR), and H1 histamine receptor (H1R) via their respective agonist. Papaya (Carica papaya L.) leaf is an herbal medicine

Externí odkaz: https://doaj.org/article/6196b3d42b4340a0b7a51b136100125e

Sterol Constituents of Sea Fan (Gorgonia mariae) as Potential Candidates of MPro Protein SARS-CoV-2 Inhibitor: in silico Study

Autor: Faruk Jayanto Kelutur

Publikováno v: Indonesian Journal of Chemical Research, Vol 9, Iss 3 (2022)

Ethnobotanically, sea fan was a group of gorgonian coral that have used the Maluku people as medicinal ingredients with secondary metabolites containing sterols, terpenoids, and alkaloids that have anti-inflammatory, anti-viral, anti-cancer, analgesi

Externí odkaz: https://doaj.org/article/3eb103483bce42af85178585951aea11

In Silico Studies: Virtual Screening Of The Compound Of Sea Fan (Gorgonia Mariae) As Antiasthmatic

Autor: Faruk Jayanto Kelutur, Resmi Mustarichie

Publikováno v: Asian Journal of Pharmaceutical Research and Development. 9:16-23

Sterol is a secondary metabolites for a group of steroids that can treat a disease caused by synergistic effect between compound of metabolite with polyvalent activity. Sea fan (G. mariae) has a major compound (sterol) that has been used by the socie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::98ba92f41f976a210fa85f1dc92b7b65
https://doi.org/10.22270/ajprd.v9i6.1041

Potential anti-alopecia constituents from Theobroma cacao: An in silico study

Autor: Faruk Jayanto Kelutur, Dikdik Kurnia, Resmi Mustarichie

Publikováno v: Journal of Advanced Pharmaceutical Technology & Research, Vol 12, Iss 2, Pp 169-174 (2021)
Journal of Advanced Pharmaceutical Technology & Research

Tinea capitis is local alopecia caused by a dermatophyte infection of the scalp. Trichophyton rubrum produces the squalene epoxidase enzyme, which has a crucial role in prolonged dermatophyte infection, as well as in synthesizing fatty acids in this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5234b1dbe94c846aa051b144bde03a70
http://www.japtr.org/article.asp?issn=2231-4040

Flavonoid Compounds of Buah Merah (Pandanus conoideus Lamk) as a Potent Oxidative Stress Modulator in ROS-induced Cancer: In Silico Approach

Autor: Faruk Jayanto Kelutur, James H. Zothantluanga, Abd. Kakhar Umar

Publikováno v: Majalah Obat Tradisional; Vol 26, No 3 (2021); 221-232

Buah Merah, a typical fruit from Papua, Indonesia which is used empirically in cancer therapy is rich in carotenoids and flavonoids. However, the mechanisms by which Buah Merah ameliorates cancer remained unknown. Natural antioxidant enzymes and pro-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3932413e26d51630c24f5204d1c731
https://doi.org/10.22146/mot.70177