Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Faruk G. Sheikh"'
Autor:
Natalia A Ilyushina, Vladimir Y Lugovtsev, Anastasia P Samsonova, Faruk G Sheikh, Nicolai V Bovin, Raymond P Donnelly
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181999 (2017)
Influenza A viruses pose a constant potential threat to human health. In view of the innate antiviral activity of interferons (IFNs) and their potential use as anti-influenza agents, it is important to know whether viral resistance to these antiviral
Externí odkaz:
https://doaj.org/article/2c516d0fe02f4b2598146900a8b03271
Autor:
Charles E. Wood, Xiaojuan Liu, Michael McKinney, Faruk G. Sheikh, John R. Raymond, Kalipada Pahan
Publikováno v:
Journal of Neurochemistry. 74:2288-2295
The present study underlines the importance of p21(ras) in regulating the inducible nitric oxide synthase (iNOS) in primary astrocytes. Bacterial lipopolysaccharides induced the GTP loading of p21(ras), and the expression of a dominant-negative mutan
Induction of Nitric-oxide Synthase and Activation of NF-κB by Interleukin-12 p40 in Microglial Cells
Autor:
Kalipada Pahan, Thomas M. Petro, Xiaojuan Liu, Michael McKinney, Shilo Hilger, Faruk G. Sheikh
Publikováno v:
Journal of Biological Chemistry. 276:7899-7905
Interleukin-12 (IL-12) is composed of two different subunits, p40 and p35. Expression of p40 mRNA but not that of p35 mRNA in excessive amount in the central nervous system of patients with multiple sclerosis (MS) suggests that IL-12 p40 may have a r
Publikováno v:
Genome. 43:981-987
A PstI family of SINEs (short interspersed elements) has been identified in some of the members of the family Bovidae, for example, cattle, buffalo and goat. In vitro DNA-protein interactions were studied to provide a better understanding of the func
Publikováno v:
Genome. 43:981-987
Autor:
Kohtaro Asayama, Rajat Sandhir, Faruk G. Sheikh, Hidemasa Hayashibe, Takaya Nakane, Inderjit Singh
Publikováno v:
Molecular and Cellular Biochemistry. 194:227-234
To determine whether the increased fatty acid beta-oxidation in the peroxisomes of diabetic rat liver is mediated by a common peroxisome proliferation mechanism, we measured the activation of long-chain (LC) and very long chain (VLC) fatty acids cata
Publikováno v:
Free Radical Biology and Medicine. 24:39-48
The present study underscores the importance of N-acetyl cysteine (NAC), a potent antioxidant, in inhibiting the induction of NO production by lipopolysaccharides (LPS) and cytokines in peritoneal macrophages, C6 glial cells and primary astrocytes. L
Publikováno v:
Journal of Clinical Investigation. 100:2671-2679
This study explores the role of mevalonate inhibitors in the activation of NF-kbeta and the induction of inducible nitric oxide synthase (iNOS) and cytokines (TNF-alpha, IL-1beta, and IL-6) in rat primary astrocytes, microglia, and macrophages. Lovas
Publikováno v:
Biochemical and Molecular Medicine. 61:198-207
The peroxisomal disorders represent a group of inherited metabolic disorders that derive from defects of peroxisomal biogenesis and/or from dysfunction of single or multiple peroxisomal enzymes. We described earlier an 8 1/2 year-old with a history o
Autor:
Harold L. Dickensheets, Laura Helming, Siamon Gordon, Raymond P. Donnelly, Faruk G. Sheikh, Thirumalai R. Ramalingam
Publikováno v:
Cytokine. 76:72
Macrophages coexpress both the interleukin (IL)-2R-gamma chain ( γ c) and IL-13R-alpha 1. These receptor chains can heterodimerize with IL-4R α to form type I or type II IL-4 receptor complexes, respectively. We used macrophages derived from Il2rg