Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Farsaneh Sadeghlar"'
Autor:
Michael Praktiknjo, Ana S. Pena Solano, Farsaneh Sadeghlar, Thomas Welchowski, Matthias Schmid, Christian Möhring, Taotao Zhou, Robert Mahn, Malte B. Monin, Carsten Meyer, Georg Feldmann, Peter Brossart, Cornelius van Beekum, Alexander Semaan, Hanno Matthaei, Steffen Manekeller, Alois M. Sprinkart, Sebastian Nowak, Julian Luetkens, Jörg C. Kalff, Christian P. Strassburg, Maria A. González-Carmona
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Lenvatinib is a multiple receptor tyrosine kinase inhibitor (TKI) approved for first-line treatment of patients with unresectable hepatocellular carcinoma (HCC). TKI are suspected of exacerbating muscle loss in patients with cancer. In this
Externí odkaz:
https://doaj.org/article/e8b3f61e90fe4943b829122cfda08c0d
Autor:
Milka Marinova, David-Alexis Khouri, Jim Küppers, Olga Ramig, Holger M. Strunk, Johannes Breuers, Julia Fazaal, Christine Fuhrmann, Martin Coenen, Christian Möhring, Taotao Zhou, Xin Zhou, Thomas Anhalt, Farsaneh Sadeghlar, Marcus Thudium, Rupert Conrad, Georg Feldmann, Peter Brossart, Tim R. Glowka, Jörg C. Kalff, Markus Essler, Christian P. Strassburg, Yon-Dschun Ko, Ingo G. H. Schmidt-Wolf, Maria Gonzalez-Carmona
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 13, p 3717 (2024)
Background: Pancreatic adenocarcinoma (PaC) still has a dismal prognosis, and despite medical advances, a bleak 5-year survival rate of only 8%, largely due to late diagnosis and limited curative surgical options for most patients. Frontline palliati
Externí odkaz:
https://doaj.org/article/7a4d5305890f40fda7bc1c01b83c7dd3
Autor:
Christian Möhring, Oliver Khan, Taotao Zhou, Farsaneh Sadeghlar, Robert Mahn, Dominik J. Kaczmarek, Leona Dold, Marieta Toma, Milka Marinova, Tim R. Glowka, Hanno Matthaei, Steffen Manekeller, Jörg C. Kalff, Christian P. Strassburg, Tobias J. Weismüller, Maria A. Gonzalez-Carmona
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Background and aimsExtrahepatic cholangiocarcinoma (eCCA) remains a malignancy with a dismal prognosis. The first-line standard of care includes systemic chemotherapy (SC) and biliary drainage through stenting. Endobiliary ablative techniques, such a
Externí odkaz:
https://doaj.org/article/0b952731a7d44f65981ea69ab330071a
Autor:
Maria A. Gonzalez-Carmona, Christian Möhring, Robert Mahn, Taotao Zhou, Alexandra Bartels, Farsaneh Sadeghlar, Maximilian Bolch, Annabelle Vogt, Dominik J. Kaczmarek, Dominik J. Heling, Leona Dold, Jacob Nattermann, Vittorio Branchi, Hanno Matthaei, Steffen Manekeller, Jörg C. Kalff, Christian P. Strassburg, Raphael U. Mohr, Tobias J. Weismüller
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Prognosis of patients with advanced extrahepatic cholangiocarcinoma (eCCA) is poor. The current standard first-line treatment is systemic chemotherapy (CT) with gemcitabine and a platinum derivate. Additionally, endobiliary radiofrequency ab
Externí odkaz:
https://doaj.org/article/b20bdd9d2fbb42d9a6274f9ec40ae8ec
Autor:
Malte Benedikt Monin, Leona I. Baier, Jens G. Gorny, Moritz Berger, Taotao Zhou, Robert Mahn, Farsaneh Sadeghlar, Christian Möhring, Christoph Boesecke, Kathrin van Bremen, Jürgen K. Rockstroh, Christian P. Strassburg, Anna-Maria Eis-Hübinger, Matthias Schmid, Maria A. Gonzalez-Carmona
Publikováno v:
Liver Cancer, Pp 1-1 (2023)
Background: Data on immune response rates following vaccination for SARS-CoV-2 in patients with hepatobiliary carcinoma (HBC) are rare. However, impaired immunogenicity must be expected due to the combination of chronic liver diseases (CLD) with mali
Externí odkaz:
https://doaj.org/article/9ae113d46a314d4e888435c13ca010d2
Autor:
Taotao Zhou, Robert Mahn, Christian Möhring, Farsaneh Sadeghlar, Carsten Meyer, Marieta Toma, Barbara Kreppel, Markus Essler, Tim Glowka, Hanno Matthaei, Jörg C. Kalff, Christian P. Strassburg, Maria A. Gonzalez-Carmona
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Cholangiocarcinoma (CCA) still has a poor prognosis and remains a major therapeutic challenge. When curative resection is not possible, palliative systemic chemotherapy with gemcitabine and platinum derivate as first line followed by a 5-FU doublet c
Externí odkaz:
https://doaj.org/article/1cc4ab4e0f624aff91005319175a59fb
Autor:
Christian Möhring, Jan Feder, Raphael U. Mohr, Farsaneh Sadeghlar, Alexandra Bartels, Robert Mahn, Taotao Zhou, Milka Marinova, Georg Feldmann, Peter Brossart, Martin von Websky, Hanno Matthaei, Steffen Manekeller, Tim Glowka, Jörg C. Kalff, Tobias J. Weismüller, Christian P. Strassburg, Maria A. Gonzalez-Carmona
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ObjectivePrognosis of patients with irresectable cholangiocarcinoma is still poor. The ABC-02 trial established the current first line (1L) standard systemic chemotherapy (CT) with gemcitabine/platinum derivate for advanced cholangiocarcinoma. Howeve
Externí odkaz:
https://doaj.org/article/3a0b0c8729054bd493c1b136c9000bca
Autor:
Annabelle Vogt, Farsaneh Sadeghlar, Tiyasha H. Ayub, Carlo Schneider, Christian Möhring, Taotao Zhou, Robert Mahn, Alexandra Bartels, Michael Praktiknjo, Miroslaw T. Kornek, Marieta Toma, Ingo G. H. Schmidt-Wolf, Vittorio Branchi, Hanno Matthaei, Jörg C. Kalff, Christian P. Strassburg, Maria A. Gonzalez-Carmona
Publikováno v:
Cancers, Vol 13, Iss 13, p 3375 (2021)
Dendritic cells (DC) as professional antigen presenting cells are able to prime T-cells against the tumor-associated antigen α-fetoprotein (AFP) for immunotherapy of hepatocellular carcinoma (HCC). However, a strong immunosuppressive tumor environme
Externí odkaz:
https://doaj.org/article/401131db7af3463584c2c76e33319524
Autor:
Christian Möhring, Adrianna Mańczak, Aliki Timotheou, Farsaneh Sadeghlar, Taotao Zhou, Robert Mahn, Malte B. Monin, Marieta Toma, Georg Feldmann, Peter Brossart, Mümtaz Köksal, Gustavo R. Sarria, Nils Sommer, Philipp Lingohr, Azin Jafari, Jörg C. Kalff, Christian P. Strassburg, Maria A. Gonzalez‐Carmona
Publikováno v:
International Journal of Cancer.
Autor:
Christian Möhring, Aliki Timotheou, Adrianna Mańczak, Farsaneh Sadeghlar, Taotao Zhou, Robert Mahn, Alexandra Bartels, Malte Monin, Marieta Toma, Georg Feldmann, Peter Brossart, Mümtaz Köksal, Gustavo R. Sarria, Frank A. Giordano, Philipp Lingohr, Azin Jafari, Jörg C. Kalff, Christian P. Strassburg, Maria A. Gonzalez-Carmona
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 149:1849-1862
Fluorouracil, leucovorin, oxaliplatin and docetaxel (FLOT) regimen has shown strong efficacy as perioperative therapy for patients with locally advanced gastric (GC) and gastroesophageal (AEG) carcinoma. In the palliative situation, FLOT is recommend