Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Farruk M. Lutful Kabir"'
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 57:519-530
The cyclin-dependent kinase inhibitors (CKIs) belong to a group of key cell cycle proteins that regulate important cancer drug targets such as the cyclin/CDK complexes. Gene defects in the INK4A/B CKI tumor suppressor locus are frequently associated
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 57(5)
The cyclin-dependent kinase inhibitors (CKIs) belong to a group of key cell cycle proteins that regulate important cancer drug targets such as the cyclin/CDK complexes. Gene defects in the INK4A/B CKI tumor suppressor locus are frequently associated
Autor:
Gang Liu, Marina Mazur, Namasivayam Ambalavanan, William T. Gerthoffer, Peng Li, William T. Harris, Tomasz Szul, Farruk M. Lutful Kabir, Brian Halloran, George M. Solomon, Steven M. Rowe, Charitharth Vivek Lal
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 197:632-643
Rationale: MicroRNAs (miRNAs) destabilize mRNA transcripts and inhibit protein translation. miR-145 is of particular interest in cystic fibrosis (CF) as it has a direct binding site in the 3′-untranslated region of CFTR (cystic fibrosis transmembra
Publikováno v:
Veterinary Sciences, Vol 3, Iss 1, p 1 (2015)
Breast cancer represents the second most frequent neoplasm in humans and sexually intact female dogs after lung and skin cancers, respectively. Many similar features in human and dog cancers including, spontaneous development, clinical presentation,
Externí odkaz:
https://doaj.org/article/2b7ac6fb063a48c08cca8ef5b81af0b6
Autor:
E. Gisela Martinez-Romero, Annette N. Smith, Farruk M. Lutful Kabir, Allison E. Church Bird, Patricia DeInnocentes, Bruce F. Smith, R. Curtis Bird
Publikováno v:
Journal of Veterinary Science
Breast cancer is among the most common malignancies affecting women and reproductively intact female dogs, resulting in death from metastatic disease if not treated effectively. To better manage the disease progression, canine mammary tumor (CMT) cel
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 199:1444-1445
Publikováno v:
Journal of Cellular Biochemistry. 116:2956-2969
microRNA (miRNA) expression profiling of cancer versus normal cells may reveal the characteristic regulatory features that can be correlated to altered gene expression in both human and animal models of cancers. In this study, the comprehensive expre
Autor:
William T. Harris, Namasivayam Ambalavanan, Weifeng Zhang, Masheika L. James, Brian Halloran, Stephanie B. Wall, Changchun Ren, Teodora Nicola, Mark MacEwen, Tatjana Coric, Farruk M. Lutful Kabir
Publikováno v:
Physiological Reports
Endoglin (ENG) regulates signaling by transforming growth factor‐β (TGF‐β), a genetic modifier of cystic fibrosis (CF) lung disease severity. We hypothesized that ENG mediates TGF‐β pathobiology in CF airway epithelia. Comparing CF and non
Autor:
Farruk M Lutful, Kabir, Patricia, DeInnocentes, Payal, Agarwal, Christopher P, Mill, David J, Riese Nd, R Curtis, Bird
Publikováno v:
Journal of Veterinary Science
Well characterized, stable, p16-defective canine mammary cancer (CMT) cell lines and normal canine mammary epithelial cells were used to investigate expression of the major breast cancer-specific hormone receptors estrogen receptor alpha (ER1) and pr
Publikováno v:
Journal of Clinical and Translational Science
OBJECTIVES/SPECIFIC AIMS: CFTR is the mutant protein that causes cystic fibrosis (CF), a fatal respiratory diseases affecting 1 in 3500 children. CFTR modulators are small molecules that directly address mutant CFTR function. Improving correction of