Preclinical evaluation of therapeutic vaccines for chronic hepatitis B that stimulate antiviral activities of T cells and NKT cells.

Autor: Mooney AH; Malaghan Institute of Medical Research, Wellington, New Zealand., Draper SL; Ferrier Research Institute, Victoria University of Wellington, Wellington, New Zealand., Burn OK; Malaghan Institute of Medical Research, Wellington, New Zealand., Anderson RJ; Ferrier Research Institute, Victoria University of Wellington, Wellington, New Zealand., Compton BJ; Ferrier Research Institute, Victoria University of Wellington, Wellington, New Zealand., Tang C; Malaghan Institute of Medical Research, Wellington, New Zealand., Farrand KJ; Malaghan Institute of Medical Research, Wellington, New Zealand., Di Lucia P; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Ravà M; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Fumagalli V; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Giustini L; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy., Bono E; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy., Godfrey DI; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Victoria, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Parkville, Australia., Heath WR; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Victoria, Australia., Yuan W; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Chisari FV; Department of Immunology & Microbial Sciences, The Scripps Research Institute, La Jolla, CA, USA., Guidotti LG; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Iannacone M; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Sidney J; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, USA., Sette A; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, USA., Gulab SA; Ferrier Research Institute, Victoria University of Wellington, Wellington, New Zealand.; Avalia Immunotherapies Limited, Wellington, New Zealand., Painter GF; Ferrier Research Institute, Victoria University of Wellington, Wellington, New Zealand., Hermans IF; Malaghan Institute of Medical Research, Wellington, New Zealand.

Publikováno v: JHEP reports : innovation in hepatology [JHEP Rep] 2024 Feb 12; Vol. 6 (5), pp. 101038. Date of Electronic Publication: 2024 Feb 12 (Print Publication: 2024).

MAIT cells activate dendritic cells to promote T FH cell differentiation and induce humoral immunity.

Autor: Pankhurst TE; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand; Malaghan Institute of Medical Research, Wellington 6242, New Zealand., Buick KH; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand; Malaghan Institute of Medical Research, Wellington 6242, New Zealand., Lange JL; Malaghan Institute of Medical Research, Wellington 6242, New Zealand., Marshall AJ; Ferrier Research Institute, Victoria University of Wellington, Wellington 6012, New Zealand., Button KR; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand., Palmer OR; Malaghan Institute of Medical Research, Wellington 6242, New Zealand., Farrand KJ; Malaghan Institute of Medical Research, Wellington 6242, New Zealand., Montgomerie I; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand., Bird TW; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand., Mason NC; Malaghan Institute of Medical Research, Wellington 6242, New Zealand., Kuang J; Department of Microbiology and Immunology, University of Otago, Dunedin 9016, New Zealand., Compton BJ; Ferrier Research Institute, Victoria University of Wellington, Wellington 6012, New Zealand., Comoletti D; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand., Salio M; Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK., Cerundolo V; Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK., Quiñones-Mateu ME; Department of Microbiology and Immunology, University of Otago, Dunedin 9016, New Zealand., Painter GF; Ferrier Research Institute, Victoria University of Wellington, Wellington 6012, New Zealand., Hermans IF; Malaghan Institute of Medical Research, Wellington 6242, New Zealand., Connor LM; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand; Malaghan Institute of Medical Research, Wellington 6242, New Zealand. Electronic address: lisa.connor@vuw.ac.nz.

Publikováno v: Cell reports [Cell Rep] 2023 Apr 25; Vol. 42 (4), pp. 112310. Date of Electronic Publication: 2023 Mar 28.

Glycolipid-peptide vaccination induces liver-resident memory CD8 ⁺ T cells that protect against rodent malaria.

Autor: Holz LE; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, VIC, Australia., Chua YC; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia., de Menezes MN; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia., Anderson RJ; Ferrier Research Institute, Victoria University of Wellington, Lower Hutt, New Zealand., Draper SL; Ferrier Research Institute, Victoria University of Wellington, Lower Hutt, New Zealand., Compton BJ; Ferrier Research Institute, Victoria University of Wellington, Lower Hutt, New Zealand., Chan STS; Ferrier Research Institute, Victoria University of Wellington, Lower Hutt, New Zealand., Mathew J; Ferrier Research Institute, Victoria University of Wellington, Lower Hutt, New Zealand., Li J; Department of Microbiology, Biomedical Discovery Institute, Monash University, Clayton, VIC, Australia., Kedzierski L; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.; Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Melbourne, VIC, Australia., Wang Z; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia., Beattie L; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, VIC, Australia., Enders MH; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, VIC, Australia.; LIMES Institute, University of Bonn, Bonn, Germany., Ghilas S; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, VIC, Australia., May R; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia., Steiner TM; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, VIC, Australia., Lange J; Malaghan Institute of Medical Research, Wellington, New Zealand., Fernandez-Ruiz D; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia., Valencia-Hernandez AM; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.; Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany., Osmond TL; Malaghan Institute of Medical Research, Wellington, New Zealand.; Avalia Immunotherapies Limited, Lower Hutt, New Zealand., Farrand KJ; Malaghan Institute of Medical Research, Wellington, New Zealand., Seneviratna R; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia., Almeida CF; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, VIC, Australia., Tullett KM; Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia., Bertolino P; Centenary Institute, The University of Sydney and AW Morrow Gastroenterology and Liver Centre, Liver Immunology Program, Newtown, NSW, Australia., Bowen DG; Centenary Institute, The University of Sydney and AW Morrow Gastroenterology and Liver Centre, Liver Immunology Program, Newtown, NSW, Australia., Cozijnsen A; School of BioSciences, University of Melbourne, Parkville, VIC, Australia., Mollard V; School of BioSciences, University of Melbourne, Parkville, VIC, Australia., McFadden GI; School of BioSciences, University of Melbourne, Parkville, VIC, Australia., Caminschi I; Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia., Lahoud MH; Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia., Kedzierska K; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia., Turner SJ; Department of Microbiology, Biomedical Discovery Institute, Monash University, Clayton, VIC, Australia., Godfrey DI; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, VIC, Australia., Hermans IF; Malaghan Institute of Medical Research, Wellington, New Zealand. wrheath@unimelb.edu.au gavin.painter@vuw.ac.nz.; Avalia Immunotherapies Limited, Lower Hutt, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Wellington, New Zealand., Painter GF; Ferrier Research Institute, Victoria University of Wellington, Lower Hutt, New Zealand. wrheath@unimelb.edu.au gavin.painter@vuw.ac.nz.; Avalia Immunotherapies Limited, Lower Hutt, New Zealand., Heath WR; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia. wrheath@unimelb.edu.au gavin.painter@vuw.ac.nz.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, VIC, Australia.

Publikováno v: Science immunology [Sci Immunol] 2020 Jun 26; Vol. 5 (48).

Augmenting Influenza-Specific T Cell Memory Generation with a Natural Killer T Cell-Dependent Glycolipid-Peptide Vaccine.

Autor: Anderson RJ; The Ferrier Research Institute, Victoria University of Wellington , PO Box 33436, Lower Hutt 5046, New Zealand., Li J; Department of Microbiology, Biomedical Discovery Institute, Monash University , Clayton, Victoria 3800, Australia., Kedzierski L; Department of Microbiology, Biomedical Discovery Institute, Monash University , Clayton, Victoria 3800, Australia., Compton BJ; The Ferrier Research Institute, Victoria University of Wellington , PO Box 33436, Lower Hutt 5046, New Zealand., Hayman CM; The Ferrier Research Institute, Victoria University of Wellington , PO Box 33436, Lower Hutt 5046, New Zealand., Osmond TL; Malaghan Institute of Medical Research , PO Box 7060, Wellington 6242, New Zealand., Tang CW; Malaghan Institute of Medical Research , PO Box 7060, Wellington 6242, New Zealand., Farrand KJ; Malaghan Institute of Medical Research , PO Box 7060, Wellington 6242, New Zealand., Koay HF; Department of Microbiology and Immunology, at the Doherty Institute for Infection and Immunity, The University of Melbourne , 792 Elizabeth St, Melbourne, Victoria 3010, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne , Parkville, Victoria 3010, Australia., Almeida CFDSSE; Department of Microbiology and Immunology, at the Doherty Institute for Infection and Immunity, The University of Melbourne , 792 Elizabeth St, Melbourne, Victoria 3010, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne , Parkville, Victoria 3010, Australia., Holz LR; Department of Microbiology and Immunology, at the Doherty Institute for Infection and Immunity, The University of Melbourne , 792 Elizabeth St, Melbourne, Victoria 3010, Australia., Williams GM; School of Biological Sciences, The University of Auckland , 3 Symonds St, Auckland Central 1142, New Zealand., Brimble MA; School of Biological Sciences, The University of Auckland , 3 Symonds St, Auckland Central 1142, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland , 3 Symonds St, Auckland Central 1142, New Zealand., Wang Z; Department of Microbiology and Immunology, at the Doherty Institute for Infection and Immunity, The University of Melbourne , 792 Elizabeth St, Melbourne, Victoria 3010, Australia., Koutsakos M; Department of Microbiology and Immunology, at the Doherty Institute for Infection and Immunity, The University of Melbourne , 792 Elizabeth St, Melbourne, Victoria 3010, Australia., Kedzierska K; Department of Microbiology and Immunology, at the Doherty Institute for Infection and Immunity, The University of Melbourne , 792 Elizabeth St, Melbourne, Victoria 3010, Australia., Godfrey DI; Department of Microbiology and Immunology, at the Doherty Institute for Infection and Immunity, The University of Melbourne , 792 Elizabeth St, Melbourne, Victoria 3010, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne , Parkville, Victoria 3010, Australia., Hermans IF; Malaghan Institute of Medical Research , PO Box 7060, Wellington 6242, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland , 3 Symonds St, Auckland Central 1142, New Zealand.; Avalia Immunotherapies Limited , Gracefield Innovation Quarter, 69 Gracefield Rd, Lower Hutt 5010, New Zealand., Turner SJ; Department of Microbiology, Biomedical Discovery Institute, Monash University , Clayton, Victoria 3800, Australia., Painter GF; The Ferrier Research Institute, Victoria University of Wellington , PO Box 33436, Lower Hutt 5046, New Zealand.; Avalia Immunotherapies Limited , Gracefield Innovation Quarter, 69 Gracefield Rd, Lower Hutt 5010, New Zealand.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2017 Nov 17; Vol. 12 (11), pp. 2898-2905. Date of Electronic Publication: 2017 Oct 27.

Activated NKT Cells Can Condition Different Splenic Dendritic Cell Subsets To Respond More Effectively to TLR Engagement and Enhance Cross-Priming.

Autor: Osmond TL; Malaghan Institute of Medical Research, Wellington 6242, New Zealand; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand;, Farrand KJ; Malaghan Institute of Medical Research, Wellington 6242, New Zealand;, Painter GF; The Ferrier Research Institute, Victoria University of Wellington, Lower Hutt 5010, New Zealand; and., Ruedl C; School of Biological Sciences, Nanyang Technological University, Singapore 637551., Petersen TR; Malaghan Institute of Medical Research, Wellington 6242, New Zealand;, Hermans IF; Malaghan Institute of Medical Research, Wellington 6242, New Zealand; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand; ihermans@malaghan.org.nz.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2015 Aug 01; Vol. 195 (3), pp. 821-31. Date of Electronic Publication: 2015 Jun 15.