Anticancer Activities of Tetrasubstituted Imidazole-Pyrimidine-Sulfonamide Hybrids as Inhibitors of EGFR Mutants.

Autor: Alghamdi EM; Department of Chemistry, Faculty of Science, King Abdulaziz University, Jeddah, 21589, Saudi Arabia., Alamshany ZM; Department of Chemistry, Faculty of Science, King Abdulaziz University, Jeddah, 21589, Saudi Arabia., El Hamd MA; Department of Pharmaceutical Sciences, College of Pharmacy, Shaqra University, Al Dwadmi, 11961, Saudi Arabia.; Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, South Valley University, Qena, 83523, Egypt., Taher ES; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut, 71524, Egypt.; Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia., Farrag El-Behairy M; Department of Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Sadat City, Menoufiya, 32897, Egypt., Norcott PL; Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia., Marzouk AA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut, 71524, Egypt.; National Center for Natural Products Research, School of Pharmacy, Mississippi University, Mississippi, MS 38677, USA.

Publikováno v: ChemMedChem [ChemMedChem] 2023 Apr 17; Vol. 18 (8), pp. e202200641. Date of Electronic Publication: 2023 Mar 01.