Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Farr Niere"'
Autor:
Taylor A. Stowe, Elizabeth G. Pitts, Amy C. Leach, Melody C. Iacino, Farr Niere, Benjamin Graul, Kimberly F. Raab-Graham, Jordan T. Yorgason, Mark J. Ferris
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110633- (2022)
Summary: Dysregulation of biological rhythms plays a role in a wide range of psychiatric disorders. We report mechanistic insights into the rhythms of rapid dopamine signals and cholinergic interneurons (CINs) working in concert in the rodent striatu
Externí odkaz:
https://doaj.org/article/e65a09e0a96340b9b7975129f73d156b
Autor:
Sarah A. Wolfe, Emily R. Workman, Chelcie F. Heaney, Farr Niere, Sanjeev Namjoshi, Luisa P. Cacheaux, Sean P. Farris, Michael R. Drew, Boris V. Zemelman, R. Adron Harris, Kimberly F. Raab-Graham
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Alcohol is thought to lead to neuroadaptive changes, although the underlying molecular mechanisms are unclear. Here, the authors find ethanol treatment alters GABAB-receptor expression via fragile-X mental retardation protein in mice, leading to anti
Externí odkaz:
https://doaj.org/article/e5cec5c74cef40f9abc05988792bd8e3
Publikováno v:
Neurobiology of Disease, Vol 73, Iss , Pp 96-105 (2015)
Changes in ion channel expression are implicated in the etiology of epilepsy. However, the molecular leading to long-term aberrant expression of ion channels are not well understood. The mechanistic/mammalian target of rapamycin (mTOR) is a serine/th
Externí odkaz:
https://doaj.org/article/b62f6df02b114c0eb14f3695ec73f766
Autor:
Farr Niere, Kimberly F. Raab-Graham
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
The mammalian/mechanistic target of rapamycin complex 1 (mTORC1) serves as a regulator of mRNA translation. Recent studies suggest that mTORC1 may also serve as a local, voltage sensor in the postsynaptic region of neurons. Considering biochemical, b
Externí odkaz:
https://doaj.org/article/23ebbb9980f24994b8ea8c9de29b6776
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::835f03c18ca6f3d82768fbc75ed4712c
https://doi.org/10.1002/alz.058557
https://doi.org/10.1002/alz.058557
Autor:
Ayse Uneri, Farr Niere, Shannon L Macauley, Tao Ma, C. Dirk Keene, Suzanne Craft, Kimberly F Raab‐Graham
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5cb0414a0d3bbb9b66306ccd8388b9e
https://doi.org/10.1002/alz.058602
https://doi.org/10.1002/alz.058602
Publikováno v:
SSRN Electronic Journal.
Circadian rhythms and diurnal (light/dark) entrainment are evident in many systems within the central nervous system. Dysregulation of these rhythms, including those of the dopamine system, plays a role in the etiology and symptomatology of a wide ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2e925a84f881d287211999eb16b8688
https://doi.org/10.2139/ssrn.3823431
https://doi.org/10.2139/ssrn.3823431
Autor:
Farr Niere, Ayse Uneri, Colin J. McArdle, Luisa P. Cacheaux, Hailey X. Egido-Betancourt, Sanjeev Namjoshi, Cameron Reynoldson, Juan Penaranda, Xin Wang, William C. Taylor, Suzanne Craft, Christopher Dirk Keene, Tao Ma, Kimberly F. Raab-Graham
L-type voltage-dependent Ca2+ channels (L-VDCC) integrate synaptic signals to facilitate a plethora of cellular mechanisms. L-VDCC dysfunction is implicated in several neurological and psychiatric diseases. Despite their importance, signals upstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4a9460fcff465bdb24c8769f4c40ae7
https://doi.org/10.1101/2020.08.26.267260
https://doi.org/10.1101/2020.08.26.267260
Autor:
Farr Niere, Luisa P. Cacheaux, Hailey X. Egido-Betancourt, William C. Taylor, Kimberly F. Raab-Graham
Tuberous sclerosis complex (TS) is a dominant, multisystem disorder with devastating neurological symptoms. Approximately 85% of TS patients suffer from epilepsy over their lifespan and roughly 25-50% of those patients develop Autism Spectrum Disorde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1db2e13dde2dd2c81ce35760283b2bd1
https://doi.org/10.1101/2020.08.26.269209
https://doi.org/10.1101/2020.08.26.269209
Publikováno v:
Europe PubMed Central
Major depressive disorder (MDD) is a complex and heterogeneous mood disorder, making it difficult to develop a generalized, pharmacological therapy that is effective for all who suffer from MDD. Through the fortuitous discovery of N-methyl-D-aspartat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69431b1563008e55dd03b1263e779163
https://doi.org/10.1038/mp.2017.225
https://doi.org/10.1038/mp.2017.225