Caregiver burden and inflammation in parents of children with special healthcare needs

Autor: Mandy D. Bamber, Farnaz Solatikia, Philippe Gaillard, Regena Spratling

Publikováno v: Discover Psychology, Vol 3, Iss 1, Pp 1-13 (2023)

Abstract Children with special healthcare needs (CSHCN) are a vulnerable population that require specialized services and are often cared for by parents. These parents experience psychological, physiological, and potential inflammatory dysfunction re

Externí odkaz: https://doaj.org/article/59398602f4ea4ab192685aaf4c7bd340

Sex-specific associations of asthma acquisition with changes in DNA methylation during adolescence

Autor: Alemayehu Z. Wolde, Wilfried Karmaus, Rutu Patel, Susan Ewart, John W. Holloway, Caroline L Relton, Farnaz Solatikia, Ryan Arathimos, Latha Kadalayil, Hongmei Zhang, Susan M. Ring, Syed Hasan Arshad, A. J. Henderson

Publikováno v: Clin Exp Allergy
Patel, R, Solatikia, F, Zhang, H, Wolde, A, Kadalayil, L, Karmaus, W, Ewart, S, Arathimos, R S, Relton, C L, Ring, S M, Henderson, A J W, Arshad, S H & Holloway, J 2020, ' Sex-specific associations of asthma acquisition with changes in DNA methylation during adolescence ', Clinical and Experimental Allergy, vol. 51, no. 2, pp. 318-328 . https://doi.org/10.1111/cea.13776

BackgroundUnderlying biological mechanisms involved in sex differences in asthma status changes from pre‐ to post‐adolescence are unclear. DNA methylation (DNAm) has been shown to be associated with the risk of asthma.ObjectiveWe hypothesized tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197edcf4a990568a1738fc8b39beeb65
https://pubmed.ncbi.nlm.nih.gov/33150670

Age at onset of different pubertal signs in boys and girls and differential DNA methylation at age 10 and 18 years: an epigenome-wide follow-up study

Autor: Wilfried Karmaus, Su Chen, Nandini Mukherjee, John W. Holloway, Susan Ewart, Farnaz Solatikia, Yu Jiang, Hala Refaey, Hongmei Zhang, S. Hasan Arshad

Publikováno v: Human Reproduction Open

STUDY QUESTIONIs the age of onset of pubertal markers related to subsequent changes in DNA methylation (DNAm)?SUMMARY ANSWERWe identified 273 cytosine-phosphate-guanine (CpG) dinucleotides in girls and 67 CpGs in boys that were related to puberty and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4afd9117de94beb7e5628e68c374da56
https://eprints.soton.ac.uk/438945/