Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Farnaz Matin"'
Autor:
Chunjiang Wei, Ziwen Gao, Martina Knabel, Martin Ulbricht, Stefan Senekowitsch, Peter Erfurt, Norman Maggi, Bastian Zwick, Thomas Eickner, Farnaz Matin-Mann, Anne Seidlitz, Thomas Lenarz, Verena Scheper
Publikováno v:
Drug Delivery, Vol 31, Iss 1 (2024)
Background There exists an unfulfilled requirement for effective cochlear pharmacotherapy. Controlled local drug delivery could lead to effective bioavailability. The round window niche (RWN), a cavity in the middle ear, is connected to the cochlea v
Externí odkaz:
https://doaj.org/article/69350fc3c8084ce3bc83da1bb8f1d31b
Autor:
Vanessa Domsta, Christin Hänsch, Stine Lenz, Ziwen Gao, Farnaz Matin-Mann, Verena Scheper, Thomas Lenarz, Anne Seidlitz
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1276 (2023)
The local treatment of diseases by drug-eluting implants is a promising tool to enable successful therapy under potentially reduced systemic side effects. Especially, the highly flexible manufacturing technique of 3D printing provides the opportunity
Externí odkaz:
https://doaj.org/article/46564524b32a46ba87aa42cadca238cf
Autor:
Farnaz Matin-Mann, Ziwen Gao, Chunjiang Wei, Felix Repp, Eralp-Niyazi Artukarslan, Samuel John, Dorian Alcacer Labrador, Thomas Lenarz, Verena Scheper
Publikováno v:
Journal of Imaging, Vol 9, Iss 2, p 51 (2023)
The aim of this study was to develop and validate a semi-automated segmentation approach that identifies the round window niche (RWN) and round window membrane (RWM) for use in the development of patient individualized round window niche implants (RN
Externí odkaz:
https://doaj.org/article/c00c106658d54ab4849d43c87bc1c99d
Autor:
Farnaz Matin-Mann, Ziwen Gao, Jana Schwieger, Martin Ulbricht, Vanessa Domsta, Stefan Senekowitsch, Werner Weitschies, Anne Seidlitz, Katharina Doll, Meike Stiesch, Thomas Lenarz, Verena Scheper
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1242 (2022)
Postoperative restenosis in patients with external ear canal (EEC) atresia or stenosis is a common complication following canaloplasty. Our aim in this study was to explore the feasibility of using a three dimensionally (3D)-printed, patient-individu
Externí odkaz:
https://doaj.org/article/a23ea856672b4fa4b1f865d988de10b1
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254902 (2021)
Chronic infections are often connected to biofilm formation. In presence of implants, this can lead to loss of the implant. Systemic or local application of drugs is relatively ineffective in case of biofilm formation. One technique to provide antiba
Externí odkaz:
https://doaj.org/article/2a57cd2335ed446794c5002e8837c061
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1896 (2021)
Dexamethasone is widely used in preclinical studies and clinical trials to treat inner ear disorders. The results of those studies vary widely, maybe due to the different dexamethasone formulations used. Laboratory (lab) and medical grade (med) dexam
Externí odkaz:
https://doaj.org/article/cecf0fde12874e23a6167b7289a1dc51
Publikováno v:
Journal of Imaging, Vol 7, Iss 5, p 79 (2021)
Modern therapy of inner ear disorders is increasingly shifting to local drug delivery using a growing number of pharmaceuticals. Access to the inner ear is usually made via the round window membrane (RWM), located in the bony round window niche (RWN)
Externí odkaz:
https://doaj.org/article/f13e09c456dd4f02b3a2d19560963f1d
Publikováno v:
Life, Vol 10, Iss 12, p 353 (2020)
Chronic rhinosinusitis (CRS) is a common disease in the general population that is increasing in incidence and prevalence, severely affecting patients’ quality of life. Medical treatment for CRS includes self-management techniques, topical and oral
Externí odkaz:
https://doaj.org/article/60d5ed220a8e4f679a465f8e643eae91
Autor:
Robert Mau, Jamal Nazir, Ziwen Gao, Dorian Alcacer Labrador, Felix Repp, Samuel John, Thomas Lenarz, Verena Scheper, Hermann Seitz, Farnaz Matin-Mann
Publikováno v:
Current Directions in Biomedical Engineering. 8:157-160
A new approach that offers the potential for local drug delivery to the inner ear is a 3D printed, patient individualized, drug-loaded implant that precisely fits into the round window niche (RWN). Anatomically correct digital light processing (DLP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::effd2e1f1f95b47bcb1a6466a623e5dc
https://doi.org/10.1515/cdbme-2022-1041
https://doi.org/10.1515/cdbme-2022-1041
Autor:
Robert Mau, Gábor Jüttner, Ziwen Gao, Farnaz Matin, Dorian Alcacer Labrador, Felix Repp, Samuel John, Verena Scheper, Thomas Lenarz, Hermann Seitz
Publikováno v:
Current Directions in Biomedical Engineering, Vol 7, Iss 2, Pp 399-402 (2021)
Here, we demonstrate a manufacturing process for individualised, small-sized implant prototypes. Our process is promising for the manufacturing of drug-releasing (micro)implants to be implanted in the round window niche (RWN-I, solid body, free-form-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb3f4e4071a129f68b37fac1470258db
https://doi.org/10.1515/cdbme-2021-2101
https://doi.org/10.1515/cdbme-2021-2101