Autonomic changes associated with enhanced anxiety in 5-ht1a receptor knockout mice

Autor: Lucianne Groenink, Jan van der Gugten, Theo H. Hijzen, Berend Olivier, Robert A. A. Maes, Ronald S. Oosting, Tommy Pattij

Publikováno v: Pattij, T, Groenink, L, Hijzen, T H, Oosting, R S, Maes, R A A, Van der Gugten, J & Olivier, B 2002, ' Autonomic changes associated with enhanced anxiety in 5-ht 1a receptor knockout mice ', Neuropsychopharmacology, vol. 27, no. 3, pp. 380-390 . https://doi.org/10.1016/S0893-133X(02)00317-2
Neuropsychopharmacology, 27, 380-90
Neuropsychopharmacology, 27, 3, pp. 380-90
Neuropsychopharmacology, 27(3), 380-390. Nature Publishing Group

5-HT1A receptor knockout (KO) mice have been described as more anxious in various anxiety paradigms. Because anxiety is often associated with autonomic changes like elevated body temperature and tachycardia, radiotelemetry was used to study these par

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991593731857c675f29c3461ac0a3f78
https://doi.org/10.1016/s0893-133x(02)00317-2

The selective serotonin re-uptake inhibitors fluvoxamine and paroxetine differ in sexual inhibitory effects after chronic treatment

Autor: Tommy Pattij, Afke van de Plas, Marcel D. Waldinger, Ruud van Oorschot, Lique M. Coolen, Jan G. Veening, Berend Olivier

Publikováno v: Psychopharmacology, 160(3), 283-289. Springer Verlag
Psychopharmacology, 160, 3, pp. 283-9
Waldinger, M D, Van de Plas, A, Pattij, T, Van Oorschot, R, Coolen, L M, Veening, J G & Olivier, B 2002, ' The selective serotonin re-uptake inhibitors fluvoxamine and paroxetine differ in sexual inhibitory effects after chronic treatment ', Psychopharmacology, vol. 160, no. 3, pp. 283-289 . https://doi.org/10.1007/s00213-001-0980-3
Psychopharmacology, 160, 283-9

Item does not contain fulltext RATIONALE: The selective serotonin re-uptake inhibitors (SSRIs) delay orgasm and ejaculation in men. In men with rapid ejaculation it was shown that, of the SSRIs, paroxetine exerted the strongest delay in ejaculation a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::febe94a9002d22dfed4a962ad64eae27
https://doi.org/10.1007/s00213-001-0980-3

The role of hippocampal dopamine receptors in prepulse inhibition

Autor: Ellenbroek, B.A., Lubbers, L.J., Cools, A.R.

Publikováno v: European Journal of Neuroscience, 15, 1237-1243
European Journal of Neuroscience, 15, 1237-43
European Journal of Neuroscience, 15, 7, pp. 1237-43
European Journal of Neuroscience, 15, 7, pp. 1237-1243

Item does not contain fulltext Although it has long been realized that the hippocampal formation receives a projection from the midbrain dopaminergic cell groups and contains mRNA for all five dopamine receptors, the functional role of this dopaminer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2e7d48e7e4dbde31942a737cf122273f
https://hdl.handle.net/2066/253225

Effects of JL13, a pyridobenzoxazepine with potential atypical antipsychotic activity, in animal models for schizophrenia

Autor: Bart Ellenbroek, Liégeois, J. -F, Bruhwyler, J., Cools, A. R.

Publikováno v: Journal of Pharmacology and Experimental Therapeutics, 298, 386--91
Journal of Pharmacology and Experimental Therapeutics, 298, 1, pp. 386--91
Scopus-Elsevier

Item does not contain fulltext JL13 [5-(4-methylpiperazin-1-yl)-8-chloro-pyrido[2,3-b][1,5] benzoxazepine fumarate] is a substance with a close structural resemblance to clozapine. However, it is less sensitive to oxidation and may therefore have les

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::86574c4c4214069b9a78a4105d35ec42
https://hdl.handle.net/2066/186793

Prepulse inhibition and latent inhibition: the role of dopamine in the medial prefrontal cortex

Autor: S Budde, Bart A. Ellenbroek, Alexander R. Cools

Publikováno v: Neuroscience, 75, 535-542
Neuroscience, 75, pp. 535-542
Neuroscience, 75, 2, pp. 535-542

The prefrontal cortex has often been implicated in the pathophysiology of schizophrenia. Schizophrenic patients are known to suffer from certain information processing deficits, which can be detected, among others, in the prepulse inhibition and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c82bf2f75c72cebfb6bfef86279a67
https://doi.org/10.1016/0306-4522(96)00307-7