Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Farmacogenètica"'
Autor:
Manuel Busto-Iglesias, Lorena Rodríguez-Martínez, Carmen Antía Rodríguez-Fernández, Jaime González-López, Miguel González-Barcia, Begoña de Domingo, Luis Rodríguez-Rodríguez, Anxo Fernández-Ferreiro, Cristina Mondelo-García
Biological drugs, especially those targeting anti-tumour necrosis factor alpha (TNF alpha) molecule, have revolutionized the treatment of patients with non-infectious uveitis (NIU), a sight-threatening condition characterized by ocular inflammation t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3310bace701a4c83d26e2fea5bf903
http://hdl.handle.net/2445/198336
http://hdl.handle.net/2445/198336
Autor:
Fernández Torras, Adrià
[eng] In the quest for understanding complex biological systems, the scientific community has been delving into protein, chemical and disease biology, populating biomedical databases with a wealth of data and knowledge. Currently, the field of biomed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______963::28a4f5c0b14025a1b0565c6c77b67c31
http://hdl.handle.net/2445/192072
http://hdl.handle.net/2445/192072
Autor:
Padró i Miquel, Ariadna
Statistics demonstrate that over 4 billion prescriptions are issued each year in the US, however, only around 50 of them show the expected therapeutic efficacy In the US alone, the direct and indirect cost of chronic pain management can range from 56
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______963::9ede63e0894b9aa0a87b03095f74f7c6
http://hdl.handle.net/2445/191086
http://hdl.handle.net/2445/191086
Akademický článek
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Autor:
Albert Martínez-Pinteño, Patricia Gassó, Llucia Prohens, Alex G. Segura, Mara Parellada, Jerónimo Saiz-Ruiz, Manuel J. Cuesta, Miguel Bernardo, Amalia Lafuente, Sergi Mas, Natalia Rodríguez
Publikováno v:
Frontiers in Pharmacology
Dipòsit Digital de la UB
Universidad de Barcelona
Frontiers in Pharmacology, Vol 12 (2021)
Dipòsit Digital de la UB
Universidad de Barcelona
Frontiers in Pharmacology, Vol 12 (2021)
Antipsychotics (APs) are associated with weight gain and other metabolic abnormalities such as hyperglycemia, dyslipidemia and metabolic syndrome. This translational study aimed to uncover the underlying molecular mechanisms and identify the key gene
Autor:
Menden M, Wang D, Mason M, Szalai B, Bulusu K, Guan Y, Yu T, Kang J, Jeon M, Wolfinger R, Nguyen T, Zaslavskiy M, Jang I, Ghazoui Z, Ahsen M, Vogel R, Neto E, Norman T, Tang E, Garnett M, Di Veroli G, Fawell S, Stolovitzky G, Guinney J, Dry J, Saez-Rodriguez J, Abante J, Abecassis B, Aben N, Aghamirzaie D, Aittokallio T, Akhtari F, Al-lazikani B, Alam T, Allam A, Allen C, de Almeida M, Altarawy D, Alves V, Amadoz A, Anchang B, Antolin A, Ash J, Aznar V, Ba-alawi W, Bagheri M, Bajic V, Ball G, Ballester P, Baptista D, Bare C, Bateson M, Bender A, Bertrand D, Wijayawardena B, Boroevich K, Bosdriesz E, Bougouffa S, Bounova G, Brouwer T, Bryant B, Calaza M, Calderone A, Calza S, Capuzzi S, Carbonell-Caballero J, Carlin D, Carter H, Castagnoli L, Celebi R, Cesareni G, Chang H, Chen G, Chen H, Cheng L, Chernomoretz A, Chicco D, Cho K, Cho S, Choi D, Choi J, Choi K, Choi M, De Cock M, Coker E, Cortes-Ciriano I, Cserzo M, Cubuk C, Curtis C, Van Daele D, Dang C, Dijkstra T, Dopazo J, Draghici S, Drosou A, Dumontier M, Ehrhart F, Eid F, ElHefnawi M, Elmarakeby H, van Engelen B, Engin H, de Esch I, Evelo C, Falcao A, Farag S, Fernandez-Lozano C, Fisch K, Flobak A, Fornari C, Foroushani A, Fotso D, Fourches D, Friend S, Frigessi A, Gao F, Gao X, Gerold J, Gestraud P, Ghosh S, Gillberg J, Godoy-Lorite A, Godynyuk L, Godzik A, Goldenberg A, Gomez-Cabrero D, Gonen M, de Graaf C, Gray H, Grechkin M, Guimera R, Guney E, Haibe-Kains B, Han Y, Hase T, He D, He L, Heath L, Hellton K, Helmer-Citterich M, Hidalgo M, Hidru D, Hill S, Hochreiter S, Hong S, Hovig E, Hsueh Y, Hu Z, Huang J, Huang R, Hunyady L, Hwang J, Hwang T, Hwang W, Hwang Y, Isayev O, Walk O, Jack J, Jahandideh S, Ji J, Jo Y, Kamola P, Kanev G, Karacosta L, Karimi M, Kaski S, Kazanov M, Khamis A, Khan S, Kiani N, Kim A, Kim J, Kim K, Kim S, Kim Y, Kirk P, Kitano H, Klambauer G, Knowles D, Ko M, Kohn-Luque A, Kooistra A, Kuenemann M, Kuiper M, Kurz C, Kwon M, van Laarhoven T, Laegreid A, Lederer S, Lee H, Lee J, Lee Y, Leppaho E, Lewis R, Li J, Li L, Liley J, Lim W, Lin C, Liu Y, Lopez Y, Low J, Lysenko A, Machado D, Madhukar N, De Maeyer D, Malpartida A, Mamitsuka H, Marabita F, Marchal K, Marttinen P, Mason D, Mazaheri A, Mehmood A, Mehreen A, Michaut M, Miller R, Mitsopoulos C, Modos D, Van Moerbeke M, Moo K, Motsinger-Reif A, Movva R, Muraru S, Muratov E, Mushthofa M, Nagarajan N, Nakken S, Nath A, Neuvial P, Newton R, Ning Z, De Niz C, Oliva B, Olsen C, Palmeri A, Panesar B, Papadopoulos S, Park J, Park S, Pawitan Y, Peluso D, Pendyala S, Peng J, Perfetto L, Pirro S, Plevritis S, Politi R, Poon H, Porta E, Prellner I, Preuer K, Pujana M, Ramnarine R, Reid J, Reyal F, Richardson S, Ricketts C, Rieswijk L, Rocha M, Rodriguez-Gonzalvez C, Roell K, Rotroff D, de Ruiter J, Rukawa P, Sadacca B, Safikhani Z, Safitri F, Sales-Pardo M, Sauer S, Schlichting M, Seoane J, Serra J, Shang M, Sharma A, Sharma H, Shen Y, Shiga M, Shin M, Shkedy Z, Shopsowitz K, Sinai S, Skola D, Smirnov P, Soerensen I, Soerensen P, Song J, Song S, Soufan O, Spitzmueller A, Steipe B, Suphavilai C, Tamayo S, Tamborero D, Tang J, Tanoli Z, Tarres-Deulofeu M, Tegner J, Thommesen L, Tonekaboni S, Tran H, De Troyer E, Truong A, Tsunoda T, Turu G, Tzeng G, Verbeke L, Videla S, Vis D, Voronkov A, Votis K, Wang A, Wang H, Wang P, Wang S, Wang W, Wang X, Wennerberg K, Wernisch L, Wessels L, van Westen G, Westerman B, White S, Willighagen E, Wurdinger T, Xie L, Xie S, Xu H, Yadav B, Yau C, Yeerna H, Yin J, Yu M, Yun S, Zakharov A, Zamichos A, Zanin M, Zeng L, Zenil H, Zhang F, Zhang P, Zhang W, Zhao H, Zhao L, Zheng W, Zoufir A, Zucknick M, AstraZeneca-Sanger Drug Combinatio
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications, 10, 2674
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Nature Communications, 10, pp. 1-17
Nature Communications 10, 2674 (2019). doi:10.1038/s41467-019-09799-2
Dipòsit Digital de la UB
Universidad de Barcelona
Nature communications, 10 (1
AstraZeneca-Sanger Drug Combination DREAM Consortium 2019, ' Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen ', Nature Communications, vol. 10, no. 1, 2674 . https://doi.org/10.1038/s41467-019-09799-2
Nature Communications, 10:2674. Nature Publishing Group
NATURE COMMUNICATIONS
Nature Communications, 10, 1-17
Nature communications, vol 10, iss 1
Menden, M P, Wang, D, Mason, M J, Szalai, B, Bulusu, K C, Guan, Y, Yu, T, Kang, J, Jeon, M, Wolfinger, R, Nguyen, T, Zaslavskiy, M, AstraZeneca-Sanger Drug Combination DREAM Consortium, Jang, I S, Ghazoui, Z, Ahsen, M E, Vogel, R, Neto, E C, Norman, T, Tang, E K Y, Garnett, M J, Veroli, G Y D, Fawell, S, Stolovitzky, G, Guinney, J, Dry, J R & Saez-Rodriguez, J 2019, ' Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen ', Nature Communications, vol. 10, no. 1, 2674 . https://doi.org/10.1038/s41467-019-09799-2
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
r-FISABIO. Repositorio Institucional de Producción Científica
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications, 10(1):2674. Nature Publishing Group
Recercat. Dipósit de la Recerca de Catalunya
Nature Communications
Nature Communications, 10, 2674
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Nature Communications, 10, pp. 1-17
Nature Communications 10, 2674 (2019). doi:10.1038/s41467-019-09799-2
Dipòsit Digital de la UB
Universidad de Barcelona
Nature communications, 10 (1
AstraZeneca-Sanger Drug Combination DREAM Consortium 2019, ' Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen ', Nature Communications, vol. 10, no. 1, 2674 . https://doi.org/10.1038/s41467-019-09799-2
Nature Communications, 10:2674. Nature Publishing Group
NATURE COMMUNICATIONS
Nature Communications, 10, 1-17
Nature communications, vol 10, iss 1
Menden, M P, Wang, D, Mason, M J, Szalai, B, Bulusu, K C, Guan, Y, Yu, T, Kang, J, Jeon, M, Wolfinger, R, Nguyen, T, Zaslavskiy, M, AstraZeneca-Sanger Drug Combination DREAM Consortium, Jang, I S, Ghazoui, Z, Ahsen, M E, Vogel, R, Neto, E C, Norman, T, Tang, E K Y, Garnett, M J, Veroli, G Y D, Fawell, S, Stolovitzky, G, Guinney, J, Dry, J R & Saez-Rodriguez, J 2019, ' Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen ', Nature Communications, vol. 10, no. 1, 2674 . https://doi.org/10.1038/s41467-019-09799-2
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
r-FISABIO. Repositorio Institucional de Producción Científica
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications, 10(1):2674. Nature Publishing Group
Recercat. Dipósit de la Recerca de Catalunya
PubMed: 31209238
The effectiveness of most cancer targeted therapies is short-lived. Tumors often develop resistance that might be overcome with drug combinations. However, the number of possible combinations is vast, necessitating data-driven a
The effectiveness of most cancer targeted therapies is short-lived. Tumors often develop resistance that might be overcome with drug combinations. However, the number of possible combinations is vast, necessitating data-driven a
Autor:
Garikoitz Azkona, Esther Pérez-Navarro, Jordi Alberch, Sara Martínez-Torres, Montse Milà, Marta Garcia-Forn, Gerardo García-Díaz Barriga
Publikováno v:
Neurobiology of Disease, Vol 120, Iss, Pp 88-97 (2018)
Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by an expansion of a CAG repeat in the huntingtin (htt) gene, which results in an aberrant form of the protein (mhtt). This leads to motor and cognitive deficits associated w
Autor:
Andrea Urtasun, Pablo Gargallo, Salvador F. Aliño, Gladys Olivera, Vanessa Segura, Victoria Castel, Yania Yáñez, Adela Cañete, María José Herrero, Pablo Berlanga, Luis Sendra
Publikováno v:
Olivera, Gladys Urtasun Erburu, Andrea Sendra Gisbert, Luis Aliño Pellicer, Salvador F. Yáñez Peralta, Yania Segura, Vanessa Gargallo, Pablo Berlanga Charriel, Pablo Castel Sánchez, Victoria Cañete Nieto, Adela Herrero Cervera, María José 2021 Pharmacogenetics in Neuroblastoma: What Can Already Be Clinically Implemented and What Is Coming Next? International Journal Of Molecular Sciences 22 18 9815
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 9815, p 9815 (2021)
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 9815, p 9815 (2021)
Pharmacogenetics is one of the cornerstones of Personalized Precision Medicine that needs to be implemented in the routine of our patients’ clinical management in order to tailor their therapies as much as possible, with the aim of maximizing effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da895b371ac907517eb0537672b178d
https://doi.org/10.3390/ijms22189815
https://doi.org/10.3390/ijms22189815
Autor:
Eva Trevisson, Claudia Pinato, Samuela Francescato, Sanja Aveic, María José Herrero, Rosa Noguera, Alessandra Biffi, Salvador F. Aliño, Carlo Zanon, Gian Paolo Tonini, Elisabetta Viscardi, Ezequiel Monferrer, Bartolomeo Rossi, Angelica Zin, Diana Corallo, Marcella Pantile
Publikováno v:
Corallo, Diana Zanon, Carlo Pantile, Marcela Tonini, Gian Paolo Zin, Angelica Francescato, Samuela Rossi, Bartolomeo Trevisson, Eva Pinato, Claudia Monferrer, Ezequiel Noguera Salvá, Rosa Aliño Pellicer, Salvador F. Herrero Cervera, María José Biffi, Alessandra Viscardi, Elisabetta Aveic, Sanja 2021 Integrated CGH/WES Analyses Advance Understanding of Aggressive Neuroblastoma Evolution: A Case Study Cells 10 10 2695
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname
Cells, Vol 10, Iss 2695, p 2695 (2021)
Cells
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname
Cells, Vol 10, Iss 2695, p 2695 (2021)
Cells
Neuroblastoma (NB) is the most common extra-cranial malignancy in preschool children. To portray the genetic landscape of an overly aggressive NB leading to a rapid clinical progression of the disease, tumor DNA collected pre- and post-treatment has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06fa3ca2c3be11abc58d966b188f4d16
https://hdl.handle.net/10550/82849
https://hdl.handle.net/10550/82849