Výsledky vyhledávání - "Farmàcia

Investigational drugs for recurrent or primary advanced metastatic cervical cancer: what is in the clinical development pipeline?

Autor: Vergote, Ignace, ray coquard, isabelle, Lorusso, Domenica, OAKNIN, ANA, Cibula, David, Van Gorp, Toon

Publikováno v: Scientia

Recurrent cervical cancer; Combination therapy; Immunotherapy Cáncer cervical recurrente; Terapia de combinación; Inmunoterapia Càncer cervical recurrent; Teràpia combinada; Immunoteràpia Introduction: Recurrent or primary advanced metastatic ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c8bf867c757de26684aafbb70f6c6b
https://doi.org/10.1080/13543784.2023.2179483

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Compliance in Non-Clinical Development of Cell-, Gene-, and Tissue-Based Medicines: Good Practice for Better Therapies

Autor: Luis Lopez-Navas, Sílvia Torrents, Rosario Sánchez-Pernaute, Joaquim Vives

Publikováno v: Scientia

Non-clinical safety; Product development; Quality compliance Seguridad no clínica; Desarrollo de productos; Cumplimiento de calidad Seguretat no clínica; Desenvolupament de productes; Compliment de la qualitat The development of cell-, gene- and ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9322afbc0334e7fd21efb4a9b7bf3d
https://pubmed.ncbi.nlm.nih.gov/35830540

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ERANET JTC 2011: Submission and Activation of an International Academic Translational Project in Advanced Breast Cancer. Experience From the ET-FES Study

Publikováno v: Scientia
Frontiers in Medicine, Vol 8 (2022)
Frontiers in Medicine

Academic; Radiopharmaceuticals; Regulatory in Europe Acadèmic; Radiofàrmacs; Regulador a Europa Académico; Radiofármacos; Regulador en Europa Background: Academic research is important to face unmet medical needs. The Oncological community encoun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02883a8d42a349df57f64003801ae8c0
https://hdl.handle.net/11351/7838

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Última lección de cátedra de Román Casares López (UCM, 1978)

Autor: Suay Matallana, Ignacio

Publikováno v: Suay Matallana, Ignacio 2022 Última lección de cátedra de Román Casares López (UCM, 1978) Llull. Revista de la Sociedad Española de Historia de las Ciencias 45 90 239 258

Este trabajo consiste en la transcripción y contextualización de la última lección de cátedra de Román Casares López (1908-1990), catedrático de análisis químico en la Facultad de Farmacia de Madrid. Se trata de una conferencia impartida el

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2079::773106bf4ccacd54c289e83314d90976
https://hdl.handle.net/10550/86094

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Implementation of access initiatives for pharmaceutical innovations in CatSalut: towards an interated concept of health and care services model: value driven transformations

Autor: Guarga, Laura, Alonso, Enric, Roig-Izquierdo, Marta, Reyes, Anna, León, Lourdes, Pastor, Marta

Publikováno v: Scientia

Innovacions farmacèutiques; Preus; Implementació d'iniciatives d'accés; Serveis sanitaris i assistencials Innovaciones farmacéuticas; Precios; Implementación de iniciativas de acceso; Servicios sanitarios y asistenciales Pharmaceutical innovatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3991::6fec877f870453adb9d01d6a3e0c5f7a
https://hdl.handle.net/11351/6728

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Genotype-driven pharmacokinetic simulations of warfarin levels in Puerto Ricans

Autor: Camila de las Barreras, Vilmali Lopez Mejias, Victor Mangas, Leyanis Rodríguez-Vera, Gledys Reynaldo, Cornelis P. Vlaar, Jean-Christophe Monbaliu, Torsten Stelzer, Jorge Duconge, Stephanie Reyes-González

Publikováno v: Drug Metab Pers Ther
Reyes-González, Stephanie Barreras, Camila de las Reynaldo, Gledys Rodríguez-Vera, Leyanis Vlaar, Cornelis Lopez Mejias, Vilmali Monbaliu, Jean-Christophe M. Stelzer, Torsten Mangas Sanjuan, Victor Duconge,Jorge 2020 Genotype-driven pharmacokinetic simulations of warfarin levels in Puerto Ricans Drug Metabolism and Personalized Therapy 1 7
RODERIC: Repositorio Institucional de la Universitat de Valéncia
instname
RODERIC. Repositorio Institucional de la Universitat de Valéncia

Objectives The inter-individual variability of warfarin dosing has been linked to genetic polymorphisms. This study was aimed at performing genotype-driven pharmacokinetic (PK) simulations to predict warfarin levels in Puerto Ricans. Methods Analysis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::999afa895e50b60db8b21b973c3d6494
https://pubmed.ncbi.nlm.nih.gov/32809952

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An Integrated View of the Influence of Temperature, Pressure, and Humidity on the Stability of Trimorphic Cysteamine Hydrochloride

Autor: Ivo B. Rietveld, Carine Ghaddar, Bernard Do, Fathi Safta, Béatrice Nicolaï, Inès Gana, Maria Barrio, Josep-Lluís Tamarit

Publikováno v: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Recercat. Dipósit de la Recerca de Catalunya
instname

Understanding the phase behavior of pharmaceuticals is important for dosage form development and regulatory requirements, in particular after the incident with ritonavir. In the present paper, a comprehensive study of the solid-state phase behavior o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c617e90ba265c2687c8f424167d3fdca
https://pubmed.ncbi.nlm.nih.gov/26042338

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Scientific competency questions as the basis for semantically enriched open pharmacological space development

Autor: Emiliano Cuadrado Rodríguez, Gerhard F. Ecker, Christine Chichester, Manuel Pastor, Niklas Blomberg, Barbara Zdrazil, Lee Harland, Jordi Mestres, Olivier Taboureau, Antony J. Williams, Matthias Rarey, Steve Pettifer, Edgar Jacoby, Marta Pinto, Bryn Williams-Jones, Stefan Senger, Mabel Loza, Kamal Azzaoui, Victor De La Torre

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
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Azzaoui, K, Jacoby, E, Senger, S, Rodríguez, E C, Loza, M, Zdrazil, B, Pinto, M, Williams, A J, de la Torre, V, Mestres, J, Pastor, M, Taboureau, O, Rarey, M, Chichester, C, Pettifer, S, Blomberg, N, Harland, L, Williams-Jones, B & Ecker, G F 2013, ' Scientific competency questions as the basis for semantically enriched open pharmacological space development ', Drug Discovery Today, vol. 18, no. 17-18, pp. 843-852 . https://doi.org/10.1016/j.drudis.2013.05.008

Molecular information systems play an important part in modern data-driven drug discovery. They do not only support decision making but also enable new discoveries via association and inference. In this review, we outline the scientific requirements

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b683dc9dc85e2d4169fb3a019e94ebe1
http://hdl.handle.net/10230/25218

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Complete blockade of the vasorelaxant effects of Ang-(1-7) and bradykinin in murine microvessels by antagonists of the receptor Mas

Autor: Peiró, Concepción, Vallejo, Susana, Gembardt, Florian, Palacios, Erika, Novella, Susana, Azcutia, Verónica, Rodríguez-Mañas, Leocadio, Hermenegildo, Carlos, Sánchez-Ferrer, Carlos F., Walther, THOMAS

Publikováno v: Peiró, Concepción Vallejo, Susana Gembardt, Florian Palacios, Erika Novella, Susana Azcutia, Verónica Rodríguez-Mañas, Leocadio Hermenegildo, Carlos Sánchez-Ferrer, Carlos F. Walther, THOMAS 2013 Complete blockade of the vasorelaxant effects of Ang-(1-7) and bradykinin in murine microvessels by antagonists of the receptor Mas. Journal of Physiology-London 591 9 2275 2285
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname
RODERIC: Repositorio Institucional de la Universitat de Valéncia

The heptapeptide angiotensin-(1-7) is a biologically active metabolite of angiotensin II, the predominant peptide of the renin-angiotensin system. Recently, we have shown that the receptor Mas is associated with angiotensin-(1-7)-induced signalling a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1b9557cbbf5f13275c9fb034a4268e51
https://hdl.handle.net/10550/75691

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