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pro vyhledávání: '"Farlow, Deborah"'
Akademický článek
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Autor:
Allen, Eliezer M. Van, Wagle, Nikhil, Stojanov, Petar, Perrin, Danielle L., Cibulskis, Kristian, Marlow, Sara, Jane-Valbuena, Judit, Friedrich, Dennis C., Kryukov, Gregory, Carter, Scott L., McKenna, Aaron, Sivachenko, Andrey, Rosenberg, Mara, Kiezun, Adam, Voet, Douglas, Lawrence, Michael, Lichtenstein, Lee T., Gentry, Jeff G., Huang, Franklin W., Fostel, Jennifer, Farlow, Deborah, Barbie, David, Gandhi, Leena, Lander, Eric S., Gray, Stacy W., Joffe, Steven, Janne, Pasi, Garber, Judy, MacConaill, Laura, Lindeman, Neal, Rollins, Barrett, Kantoff, Philip, Fisher, Sheila A., Gabriel, Stacey, Getz, Gad, Garraway, Levi A.
Publikováno v:
Nature medicine
Translating whole-exome sequencing (WES) for prospective clinical use may have an impact on the care of patients with cancer; however, multiple innovations are necessary for clinical implementation. These include rapid and robust WES of DNA derived f
Autor:
Kiezun, Adam, Erdmann, Jeanette, Auer, Paul L., Roberts, Robert, Danesh, John, Farlow, Deborah N., Stitziel, Nathan O., Lange, Leslie A., Goel, Anuj, Shah, Svati H., Zuk, Or, Samani, Nilesh J., DePristo, Mark A., Angelica Merlini, Pier, Saleheen, Danish, Stewart, Alexander F. R., Won, Hong-Hee, Duga, Stefano, Farrall, Martin, Girelli, Domenico, Kraus, William E., Martinelli, Nicola, Epstein, Stephen E., Asselta, Rosanna, Guella, Illaria, Peloso, Gina M., Sivapalaratnam, Suthesh, Kastelein, John J., Kees Hovingh, G., Jørgensen, Anders Berg, Schunkert, Heribert, Do, Ron
Myocardial infarction (MI), a leading cause of death around the world, displays a complex pattern of inheritance1,2. When MI occurs early in life, the role of inheritance is substantially greater1. Previously, rare mutations in low-density lipoprotei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acddaab5f63a574e85f58cb0d5c6ae46
Autor:
Lange, Leslie A, Hu, Youna, Zhang, He, Xue, Chenyi, Schmidt, Ellen M, Tang, Zheng-Zheng, Bizon, Chris, Lange, Ethan M, Smith, Joshua D, Turner, Emily H, Jun, Goo, Kang, Hyun Min, Peloso, Gina, Auer, Paul, Li, Kuo-Ping, Flannick, Jason, Zhang, Ji, Fuchsberger, Christian, Gaulton, Kyle, Lindgren, Cecilia, Locke, Adam, Manning, Alisa, Sim, Xueling, Rivas, Manuel A, Holmen, Oddgeir L, Gottesman, Omri, Lu, Yingchang, Ruderfer, Douglas, Stahl, Eli A, Duan, Qing, Li, Yun, Durda, Peter, Jiao, Shuo, Isaacs, Aaron, Hofman, Albert, Bis, Joshua C, Correa, Adolfo, Griswold, Michael E, Jakobsdottir, Johanna, Smith, Albert V, Schreiner, Pamela J, Feitosa, Mary F, Zhang, Qunyuan, Huffman, Jennifer E, Crosby, Jacy, Wassel, Christina L, Do, Ron, Franceschini, Nora, Martin, Lisa W, Robinson, Jennifer G, Assimes, Themistocles L, Crosslin, David R, Rosenthal, Elisabeth A, Tsai, Michael, Rieder, Mark J, Farlow, Deborah N, Folsom, Aaron R, Lumley, Thomas, Fox, Ervin R, Carlson, Christopher S, Peters, Ulrike, Jackson, Rebecca D, van Duijn, Cornelia M, Uitterlinden, André G, Levy, Daniel, Rotter, Jerome I, Taylor, Herman A, Gudnason, Vilmundur, Siscovick, David S, Fornage, Myriam, Borecki, Ingrid B, Hayward, Caroline, Rudan, Igor, Chen, Y Eugene, Bottinger, Erwin P, Loos, Ruth JF, Sætrom, Pål, Hveem, Kristian, Boehnke, Michael, Groop, Leif, McCarthy, Mark, Meitinger, Thomas, Ballantyne, Christie M, Gabriel, Stacey B, O'Donnell, Christopher J, Post, Wendy S, North, Kari E, Reiner, Alexander P, Boerwinkle, Eric, Psaty, Bruce M, Altshuler, David, Kathiresan, Sekar, Lin, Dan-Yu, Jarvik, Gail P, Cupples, L Adrienne, Kooperberg, Charles, Wilson, James G, Nickerson, Deborah A, Abecasis, Goncalo R, Rich, Stephen S
Publikováno v:
American journal of human genetics, vol 94, iss 2
Elevated low-density lipoprotein cholesterol (LDL-C) is a treatable, heritable risk factor for cardiovascular disease. Genome-wide association studies (GWASs) have identified 157 variants associated with lipid levels but are not well suited to assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::b0c59997ecf5a9de491aa1cfc1960172
https://escholarship.org/uc/item/3w75q2zz
https://escholarship.org/uc/item/3w75q2zz
Autor:
Pankow, James S., Gabriel, Stacey B., Martin, Lisa W., Farlow, Deborah N., Lange, Ethan M., Ramachandran, Vasan S., Ballantyne, Christie M., Fox, Ervin R., Tracy, Russell P., Larkin, Emma, Durda, Peter, Keating, Brendan J., Dupuis, Josee, Gross, Myron D., Lettre, Guillaume, Ellis, Jaclyn, Schnabel, Renate B., Rotter, Jerome I., Palmer, Cameron D., Willis, Monte S., Wilson, James G., Auer, Paul, Baumert, Jens, Walston, Jeremy D., Papanicolaou, George J., Peters, Ulrike, Koenig, Wolfgang, Young, Taylor, Li, Jin, Bis, Joshua C., Meng, Yan A., Marzi, Carola S.
C-reactive protein (CRP) is a heritable biomarker of systemic inflammation and a predictor of cardiovascular disease (CVD). Large-scale genetic association studies for CRP have largely focused on individuals of European descent. We sought to uncover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d03a1e955a1a7ff925e6fa56febb6bc
Most patients with BRAF(V600)-mutant metastatic melanoma develop resistance to selective RAF kinase inhibitors. The spectrum of clinical genetic resistance mechanisms to RAF inhibitors and options for salvage therapy are incompletely understood. We p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::081d8d6d7c97a0744bb4ee5232c3af97
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3160297
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3160297
Autor:
Schnabel, Renate B., Kerr, Kathleen F., Lubitz, Steven A., Alkylbekova, Ermeg L., Marcus, Gregory M., Sinner, Moritz F., Magnani, Jared W., Wolf, Philip A., Deo, Rajat, Lloyd-Jones, Donald M., Lunetta, Kathryn L., Mehra, Reena, Levy, Daniel, Fox, Ervin R., Arking, Dan E., Mosley, Thomas H., Mueller, Martina, Young, Taylor, Wichmann, Erich, Seshadri, Sudha, Farlow, Deborah N., Rotter, Jerome I., Soliman, Elsayed Z., Glazer, Nicole L., Wilson, James G., Breteler, Monique M.B., Sotoodehnia, Nona, Newton-Cheh, Christopher, Kääb, Stefan, Ellinor, Patrick T., Alonso, Alvaro, Benjamin, Emelia J., Heckbert, Susan R.
The genetic background of atrial fibrillation (AF) in whites and African Americans is largely unknown. Genes in cardiovascular pathways have not been systematically investigated.We examined a panel of approximately 50,000 common single-nucleotide pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee6cdd3452848ca7431302e15d36533f
https://europepmc.org/articles/PMC3224824/
https://europepmc.org/articles/PMC3224824/
Autor:
Spector, Tim D., Rotimi, Charles N., Hedblad, Bo, Brand, Eva, Day, Ian N. M., Kita, Yoshikuni, Chandak, Giriraj R., Tomaszewski, Maciej, Wong, Andrew, Ogihara, Toshio, Salomaa, Veikko, Igl, Wilmar, Laitinen, Jaana, Olden, Matthias, Okamura, Tomonori, Peltonen, Leena, Witteman, Jacqueline C. M., Wichmann, H-erich, Palmer, Lyle J., Boerwinkle, Eric, Talmud, Philippa J., Tabara, Yasuharu, Platou, Carl G. P., Gyllensten, Ulf B., Meneton, Pierre, Dominiczak, Anna F., Frayling, Timothy M., Groop, Leif, Smith, Albert V., Jackson, Anne U., Kutlar, Abdullah, Heath, Simon, Voight, Benjamin F., Meitinger, Thomas, Stringham, Heather M., Gaunt, Tom R., Islam, Muhammad, Tai, E. Shyong, Hofman, Albert, Lohman, Kurt K., Rotter, Jerome I., Hoffman Bolton, Judith A., Schouw, Yvonne T., Raffel, Leslie J., Lawrence, Robert W., Rudock, Megan E., Scuteri, Angelo, Peden, John F., Eyheramendy, Susana, Aspelund, Thor, Adair, Linda S., Demirkan, Ayse, Staessen, Jan A., Glazer, Nicole L., Launer, Lenore, Ganesh, Santhi, Hirschorn, Joel N., Seshadri, Sudha, Sjö, gren, Marketa, Musani, Solomon K., Verwoert, Germaine C., Umemura, Satoshi, Bis, Joshua C., Dreisbach, Albert W., Keating, Brendan J., Ala-korpela, Mika, Hartikainen, Anna-liisa, Galan, Pilar, Strachan, David P., Hadley, David, Prokopenko, Inga, Young, J. Hunter, Ehret, Georg B., Prabhakaran, Dorairajan, Scott, Laura J., Mosley, Thomas H., Viikari, Jorma, Ohkubo, Takayoshi, Wiggins, Kerri L., Emilsson, Valur, Salako, Tunde, Vö, lker, Uwe, Bornstein, Stefan R., lzke, Henry, Dries, Daniel L., Sharma, Pankaj, Ueshima, Hirotsugu, Wright, Alan F., Lee, Nanette R., Loos, Ruth J. F., Lawlor, Debbie A., Kathiresan, Sekar, Cho, Yoon Shin, Luan, Jian An, Jafar, Tazeen H., Bakker, Stephan J. L., Altshuler, David, Arking, Dan E., Tayo, Bamidele O., Smith, George Davey, Liu, Kiang, Taylor, Herman A., Parsa, Afshin, Mattace-raso, Francesco U. S., Wild, Sarah H., Guo, Xiuqing, Shuldiner, Alan R., Zhang, Weihua, Zhang, Feng, Harris, Tamara B., Kuusisto, Johanna, Zukowska-szczechowska, Ewa, Nyberg, Fredrik, Vineis, Paolo, Dahgam, Santosh, Hayward, Caroline, Hicks, Andrew A., Kuh, Diana, Shriner, Daniel, Taylor, Andrew, Mckenzie, Colin A., Wang, Thomas J., Steinle, Nanette I., Elosua, Roberto, Sim, Xueling, Kang, Sun J., Rivadeneira, Fernando, Palmen, Jutta, Cooper, Matthew N., Lyon, Helen N., Levy, Daniel, Swift, Amy J., Raitakari, Olli, Lyytikä, inen, Leo-pekka, Saleheen, Danish, Rudan, Igor, Schwarz, Peter E. H., Kooner, Jaspal S., Smith, Nicholas L., Matullo, Giuseppe, Barroso, Inê, s, O Connell, Jeffrey R., Hunt, Steven C., Hernandez, Dena, Erdmann, Jeanette, Wü, rz, Peter, Forrester, Terrence, Burton, Paul R., Ongen, Halit, Bandinelli, Stefania, Thelle, Dag S., Sehmi, Joban S., O Reilly, Paul F., Braund, Peter S., Danesh, John, Wyatt, Sharon B., Parker, Alex N., Polak, Josef F., Collins, Rory, Zhao, Jing Hua, Shi, Gang, Dehghan, Abbas, Rosengren, Annika, Whincup, Peter H., Duijn, Cornelia M., Hwang, Shih-jen, Ridker, Paul M., Chakravarti, Aravinda, Uda, Manuela, Tanaka, Toshiko, Pramstaller, Peter P., Morken, Mario A., Soininen, Pasi, Abecasis, Gonç, alo R., Zhai, Guangju, Curb, J. David, Ferrucci, Luigi, Doumatey, Ayo P., Fox, Ervin R., Bergman, Richard N., Johnson, Toby, Larson, Martin G., Snieder, Harold, Morris, Richard W., Onland-moret, N. Charlotte, Johnson, Andrew D., Narisu, Narisu, Samani, Nilesh J., Pihur, Vasyl, Chaturvedi, Nish, Melander, Olle, Hamsten, Anders, Charchar, Fadi J., Ludwig, Barbara, Kim, Hyung-lae, Bergmann, Sven, Nalls, Michael A., Milaneschi, Yuri, Palmer, Nicholette D., Alexander, Myriam, Townsend, Raymond R., Caulfield, Mark J., Hilton, Gina, Tuomilehto, Jaakko, Lee, Jong-young, Perola, Markus, Grobbee, Diederick E., Longstreth, Will T., Munroe, Patricia B., Uitterlinden, Andre G., Iwai, Naoharu, Adeyemo, Adebowale, Cooper, Richard S., Mcardle, Wendy L., Sun, Yan V., Sijbrands, Eric J. G., Fabsitz, Richard R., Nguyen, Khanh-dung Hoang, Martin, Lisa W., Wareham, Nicholas J., Brown, Morris J., Wang, Xiaoling, Kuznetsova, Tatiana, Rao, Dabeeru C., Org, Elin, Gilst, Wiek H., Orru, Marco, Oostra, Ben A., Howard, Philip, Wagenknecht, Lynne E., Meschia, James F., Mooser, Vincent, Lehtimä, ki, Terho, Wong, Tien Y., Langefeld, Carl D., Bragg-gresham, Jennifer L., Bochud, Murielle, Arora, Pankaj, Kivimaki, Mika, Seielstad, Mark, O Donnell, Chris, Chasman, Daniel I., Farrall, Martin, Polasek, Ozren, Fava, Cristiano, Vitart, Veronique, Mani, K. Radha, Uiterwaal, Cuno S. P. M., Chang, Yen-pei C., Zhu, Haidong, Morrison, Alanna C., Bonnycastle, Lori L., Najjar, Samer, Vollenweider, Peter, Eaton, Charles B., Singleton, Andrew, Teumer, Alexander, Deloukas, Panos, Campbell, Harry, Terzic, Janos, Aulchenko, Yurii, Farlow, Deborah N., Psaty, Bruce M., Beckmann, Jacques S., Scott, James, Tobin, Martin D., Kao, Wen Hong Linda, Harst, Pim, Amin, Najaf, Zitting, Paavo, Pattaro, Cristian, Casas, Juan P., Ikram, M. Arfan, Coresh, Josef, Hingorani, Aroon D., Kulkarni, Smita R., Shrine, Nick R. G., Yao, Jie, Fowkes, F. Gerald R., Clarke, Robert, Grä, ssler, Jü, rgen, Hercberg, Serge, Wain, Louise V., Redline, Susan, Isaacs, Aaron, Hopewell, Jemma C., Lathrop, Mark, Vinay, D. G., Marmot, Michael G., Laan, Maris, Rasheed, Asif, Sõ, ber, Siim, Vartiainen, Erkki, Han, Bok-ghee, Rettig, Rainer, Kinra, Sanjay, Artigas, Maria Soler, Veldre, Gudrun, Navis, Gerjan, Shaw-hawkins, Sue, Franceschini, Nora, Lucas, Gavin, Penman, Alan D., Ong, Rick Twee-hee, Mohlke, Karen L., Beilby, John P., Zhu, Xiaofeng, Bots, Michiel L., Chen, Ming-huei, Denniff, Matthew, Brand, Stefan-martin, Kangas, Antti J., Hveem, Kristian, Chambers, John C., Tukiainen, Taru, Boehnke, Michael, Ramachandran, Vasan S., Connell, John M., Collins, Francis S., Khaw, Kay-tee, Nilsson, Peter, Wilson, James F., Yajnik, Chittaranjan S., Guarrera, Simonetta, Gieger, Christian, Elliott, Paul, Plump, Andrew, Ricceri, Fulvio, Tzoulaki, Ioanna, Garcia, Melissa, Kä, hö, nen, Mika, Laakso, Markku, Kumari, Meena, Stancá, ková, Alena, Corsi, Anna Maria, Soranzo, Nicole, Kettunen, Johannes, Gudnason, Vilmundur, Kardia, Sharon L. R., Hardy, Rebecca, Lakatta, Edward G., Goel, Anuj, Liu, Yongmei, Dong, Yanbin, Humphries, Steve E., Rice, Kenneth M., Newton-cheh, Christopher, Kö, ttgen, Anna, Viigimaa, Margus, Tripathy, Vikal, Mangino, Massimo, Janipalli, Charles S., Heckbert, Susan R., Palmas, Walter, Watkins, Hugh, Dö, rr, Marcus, Kroemer, Heyo K., Weder, Alan B., Wu, Ying, Schwartz, Steven M., Miki, Tetsuro, Zelenika, Diana, Cooper, Jackie A., Kumar, M. J. Kranthi, International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS), Jä, rvelin, Marjo-riitt, EchoGen consortium, CARDIoGRAM consortium, CKDGen consortium, Charge-hf, Consortium, KidneyGen consortium
Publikováno v:
Hum Mol Genet
Human Molecular Genetics
Human molecular genetics, vol 20, iss 11
Human Molecular Genetics, 20(11), 2273-2284. Oxford University Press
Human Molecular Genetics, Vol. 20, No 11 (2011) pp. 2273-84
Hum. Mol. Genet. 20, 2273-2284 (2011)
Fox, E R, Young, J H, Li, Y, Dreisbach, A W, Keating, B J, Musani, S K, Liu, K, Morrison, A C, Ganesh, S, Kutlar, A, Ramachandran, V S, Polak, J F, Fabsitz, R R, Dries, D L, Farlow, D N, Redline, S, Adeyemo, A, Hirschorn, J N, Sun, Y V, Wyatt, S B, Penman, A D, Palmas, W, Rotter, J I, Townsend, R R, Doumatey, A P, Tayo, B O, Mosley, T H, Lyon, H N, Kang, S J, Rotimi, C N, Cooper, R S, Franceschini, N, Curb, J D, Martin, L W, Eaton, C B, Kardia, S L R, Taylor, H A, Caulfield, M J, Ehret, G B, Johnson, T, Chakravarti, A, Zhu, X, Levy, D, Wild, S H, Rudan, I, Vitart, V, Campbell, H, Hayward, C & Wright, A F & Wilson, J F 2011, ' Association of genetic variation with systolic and diastolic blood pressure among African Americans : the Candidate Gene Association Resource study ', Human Molecular Genetics, vol. 20, no. 11, pp. 2273-84 . https://doi.org/10.1093/hmg/ddr092
Human Molecular Genetics, vol. 20, no. 11, pp. 2273-2284
Human Molecular Genetics
Human molecular genetics, vol 20, iss 11
Human Molecular Genetics, 20(11), 2273-2284. Oxford University Press
Human Molecular Genetics, Vol. 20, No 11 (2011) pp. 2273-84
Hum. Mol. Genet. 20, 2273-2284 (2011)
Fox, E R, Young, J H, Li, Y, Dreisbach, A W, Keating, B J, Musani, S K, Liu, K, Morrison, A C, Ganesh, S, Kutlar, A, Ramachandran, V S, Polak, J F, Fabsitz, R R, Dries, D L, Farlow, D N, Redline, S, Adeyemo, A, Hirschorn, J N, Sun, Y V, Wyatt, S B, Penman, A D, Palmas, W, Rotter, J I, Townsend, R R, Doumatey, A P, Tayo, B O, Mosley, T H, Lyon, H N, Kang, S J, Rotimi, C N, Cooper, R S, Franceschini, N, Curb, J D, Martin, L W, Eaton, C B, Kardia, S L R, Taylor, H A, Caulfield, M J, Ehret, G B, Johnson, T, Chakravarti, A, Zhu, X, Levy, D, Wild, S H, Rudan, I, Vitart, V, Campbell, H, Hayward, C & Wright, A F & Wilson, J F 2011, ' Association of genetic variation with systolic and diastolic blood pressure among African Americans : the Candidate Gene Association Resource study ', Human Molecular Genetics, vol. 20, no. 11, pp. 2273-84 . https://doi.org/10.1093/hmg/ddr092
Human Molecular Genetics, vol. 20, no. 11, pp. 2273-2284
The prevalence of hypertension in African Americans (AAs) is higher than in other US groups; yet, few have performed genome-wide association studies (GWASs) in AA. Among people of European descent, GWASs have identified genetic variants at 13 loci th
Autor:
Mosley, Thomas H., Wyatt, Sharon B., Liu, Kiang, Adeyemo, Adebowale, Keating, Brendan J., Kang, Sun J., Rotimi, Charles N., Dries, Daniel L., Franceschini, Nora, Tayo, Bamidele O., Rotter, Jerome I., Palmas, Walter, Li, Yali, Townsend, Raymond R., Redline, Susan, Polak, Josef F., Farlow, Deborah N., Kutlar, Abdullah, Cooper, Richard S., Penman, Alan D., Fox, Ervin R., Ramachandran, Vasan S., Sun, Yan V., Hirschorn, Joel N., Young, J. Hunter, Lyon, Helen N., Fabsitz, Richard R., Doumatey, Ayo P., Ganesh, Santhi, Morrison, Alanna C., Musani, Solomon K., Dreisbach, Albert W.
The prevalence of hypertension in African Americans (AAs) is higher than in other US groups; yet, few have performed genome-wide association studies (GWASs) in AA. Among people of European descent, GWASs have identified genetic variants at 13 loci th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::433b5aafa475d5238d58c66fc2338add
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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K zobrazení výsledku je třeba se přihlásit.