Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Farideh Ghomashchi"'
Autor:
Dawn E. Tucker, Allison Stewart, Laxman Nallan, Pravine Bendale, Farideh Ghomashchi, Michael H. Gelb, Christina C. Leslie
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 10, Pp 2122-2133 (2005)
Cytosolic phospholipase A2γ (cPLA2γ) is a member of the group IV family of intracellular phospholipase A2 enzymes, but unlike the well-studied cPLA2α, it is constitutively bound to membrane and is calcium independent. cPLA2γ contains a C-terminal
Externí odkaz:
https://doaj.org/article/e63e56491cd448e78a7ce31d1deb02e5
Autor:
František Tureček, Farideh Ghomashchi, C. Ronald Scott, Joseph J. Orsini, Joanne Kurtzberg, Hsuan-Chieh Liao, Zdenek Spacil, Michael H. Gelb, Maria L. Escolar
Publikováno v:
Clinical Chemistry. 63:1363-1369
BACKGROUND Deficiency of the lysosomal enzyme galactosylcerebrosidase (GALC) causes Krabbe disease. Newborn screening for Krabbe disease is ongoing, but improved methods for follow-up analysis of screen-positive babies are needed to better advise fam
Autor:
Michael H. Gelb, Farideh Ghomashchi, Makoto Ito, František Tureček, Arun Kumar, C. Ronald Scott, Naveen Kumar Chennamaneni, Sophia Masi, Zdenek Spacil
Publikováno v:
Clinical Chemistry. 61:1363-1371
BACKGROUND There is interest in newborn screening and diagnosis of lysosomal storage diseases because of the development of treatment options that improve clinical outcome. Assays of lysosomal enzymes with high analytical range (ratio of assay respon
Autor:
Charles W. Frevert, Ryan C. Murphy, Anne M. Manicone, Farideh Ghomashchi, Teal S. Hallstrand, Michael H. Gelb, Herbert Luke Ogden, Adrian M. Piliponsky, Dowon An, Ying Lai, James D. Nolin, William A. Altemeier, Gajendra S. Naika, Gail M. Gauvreau
Publikováno v:
JCI insight. 2(21)
Phospholipase A2 (PLA2) enzymes regulate the formation of eicosanoids and lysophospholipids that contribute to allergic airway inflammation. Secreted PLA2 group X (sPLA2-X) was recently found to be increased in the airways of asthmatics and is highly
Autor:
Christine Payré, Louise Jeammet, Gérard Lambeau, Vesna Brglez, Farideh Ghomashchi, Sofiane Bezzine, Michael H. Gelb
A family of 14-20kDa, disulfide-rich, calcium-dependent secreted phospholipases A2 (sPLA2s) that release fatty acids from the sn-2 position of glycerophospholipids can be found in mammals. They have a diverse array of tissue distribution and biologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8a26dcd66692b002769c04fd084349b
https://doi.org/10.1016/bs.mie.2016.10.034
https://doi.org/10.1016/bs.mie.2016.10.034
Autor:
Lisa DiAntonio, Melissa P. Wasserstein, Xinying Hong, Sara Violante, Farideh Ghomashchi, Erin E. Hughes, Michele Caggana, Michael H. Gelb, Na Lin, Chunli Yu, Ruth Kornreich, Hui Zhou, Hsuan-Chieh Liao, Joseph J. Orsini, Arun Kumar, Jingyu Huang, Colleen F. Stevens
Publikováno v:
Clinical chemistry. 63(4)
BACKGROUND Pompe disease (PD) is the first lysosomal storage disorder to be added to the Recommended Uniform Screening Panel for newborn screening. This condition has a broad phenotypic spectrum, ranging from an infantile form (IOPD), with severe mor
Autor:
Joseph V. Bonventre, Christina C. Leslie, Michael H. Gelb, Dawn E. Tucker, Robyn Loper, Farideh Ghomashchi, Moumita Ghosh
Publikováno v:
Journal of Biological Chemistry. 282:11676-11686
Group IVA cytosolic phospholipase A(2) (cPLA(2)alpha) initiates eicosanoid production; however, this pathway is not completely ablated in cPLA(2)alpha(-/-) lung fibroblasts stimulated with A23187 or serum. cPLA(2)alpha(+/+) fibroblasts preferentially
Autor:
Arun Kumar, František Tureček, Zdenek Spacil, C. Ronald Scott, Sophia Masi, Farideh Ghomashchi, Makoto Ito, Tomomi Sumida, Michael H. Gelb
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 451
Background Treatments have been developed for mucopolysaccharidoses IVA (MPS IVA) and MPS VI suggesting the need for eventual newborn screening. Biochemical enzyme assays are important for diagnosis. Previously reported fluorimetric assays of the rel
Autor:
Richard Lehner, Samuel Hernandez-Anzaldo, Michael H. Gelb, Zamaneh Kassiri, Makoto Murakami, Carlos Fernandez-Patron, Xiang Wang, Evan Berry, Farideh Ghomashchi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Matrix metalloproteinase ( MMP )‐2 deficiency makes humans and mice susceptible to inflammation. Here, we reveal an MMP ‐2–mediated mechanism that modulates the inflammatory response via secretory phospholipase A 2 ( sPLA 2 ), a phos
Autor:
Eva Stefanski, Eric Vachon, Farideh Ghomashchi, Gregory P. Downey, Jonathan Plumb, Barry B. Rubin, Michael H. Gelb, Michael B. Yaffe, Denis W. Harkin, ChunXiang Sun, Brian P. Smart, Glenn E. Brown, Thomas F. Lindsay, Martin Sadilek, Adeline Koh, Laxman Nallan, Norbert Degousee, David J. Kelvin, Michael Glogauer, Vera Cherepanov, Sergio Grinstein
Publikováno v:
Journal of Biological Chemistry. 280:7519-7529
The role of a cytosolic phospholipase A2-α (cPLA2-α) in neutrophil arachidonic acid release, platelet-activating factor (PAF) biosynthesis, NADPH oxidase activation, and bacterial killing in vitro, and the innate immune response to bacterial infect