Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Farideh Beigi"'
Autor:
Zhiping Zhang, Alan Payne, Maria Mirotsou, Victor J. Dzau, Richard E. Pratt, Jeffrey Schmeckpeper, Amanda Verma, Farideh Beigi, Lucy Yin, Lunan Zhang
Publikováno v:
Journal of Molecular and Cellular Cardiology. 85:215-225
Wnt signaling has recently emerged as an important regulator of cardiac progenitor cell proliferation and differentiation, but the exact mechanisms by which Wnt signaling modulates these effects are not known. Understanding these mechanisms is essent
Autor:
Pete Pow-anpongkul, James Alan Payne, Maria Mirotsou, Victor J. Dzau, Zhiping Zhang, Jeffrey Schmeckpeper, Lunan Zhang, Farideh Beigi, Jing Huang
Publikováno v:
Circulation Research. 113:372-380
Rationale: The regenerative capacity of the heart is markedly diminished shortly after birth, coinciding with overall withdrawal of cardiomyocytes from cell cycle. Consequently, the adult mammalian heart has limited capacity to regenerate after injur
Autor:
Marco A. Morales-Garza, Caitlin Winebrenner, Doris A. Taylor, Mitalben Patel, Eric Chau, Farideh Beigi, Luiz C. Sampaio, Andrea S. Gobin
Publikováno v:
Journal of cellular physiology. 232(11)
Numerous protocols exist for isolating aortic endothelial and smooth muscle cells from small animals. However, establishing a protocol for isolating pure cell populations from large animal vessels that are more elastic has been challenging. We develo
Autor:
Matthew W. Foster, Joshua M. Hare, Raul A Dulce, Khalid M. Minhas, Jonathan S. Stamler, Courtney Premer, Qi An Sun, Daniel R. Gonzalez, Roberto M. Saraiva, Ivonne Hernandez Schulman, Shakil A. Khan, Robert W. Harrison, Farideh Beigi, Adriana V. Treuer
Publikováno v:
Proceedings of the National Academy of Sciences. 109:4314-4319
Although protein S -nitrosylation is increasingly recognized as mediating nitric oxide (NO) signaling, roles for protein denitrosylation in physiology remain unknown. Here, we show that S -nitrosoglutathione reductase (GSNOR), an enzyme that governs
Publikováno v:
Proceedings of the National Academy of Sciences. 104:20612-20617
Altered Ca 2+ homeostasis is a salient feature of heart disease, where the calcium release channel ryanodine receptor (RyR) plays a major role. Accumulating data support the notion that neuronal nitric oxide synthase (NOS1) regulates the cardiac RyR
Autor:
Irving W. Wainer, Farideh Beigi
Publikováno v:
Analytical Chemistry. 75:4480-4485
Opioid receptors are members of the superfamily of G protein-coupled receptors (GPCRs). Liquid chromatographic stationary phases containing either the human mu or kappa opioid receptor subtypes have been developed to study the binding between the opi
Autor:
Farideh Beigi, Per Lundahl
Publikováno v:
Journal of Chromatography A. 852:313-317
Drug interaction with lipid bilayers was quantified by immobilized biomembrane chromatography on a series of columns containing different small amounts of human red cell membrane vesicles to extend and characterize this technique, which shows a poten
Autor:
Kristina Luthman, Per Lundahl, Katrin Palm, Per Artursson, Farideh Beigi, Gert Strandlund, Anna-Lena Ungell
Publikováno v:
Journal of Medicinal Chemistry. 41:5382-5392
The relationship between various molecular descriptors and transport of drugs across the intestinal epithelium was evaluated. The monolayer permeability (Pc) of human intestinal Caco-2 cells to a series of nine beta-receptor-blocking agents was inves
Autor:
Eggert Brekkan, Yanxiao Zhang, Lars Haneskog, Thomas Österberg, Ingo Gottschalk, Christine Lagerquist Hägglund, Per Lundahl, Farideh Beigi
Publikováno v:
International Journal of Pharmaceutics. 164:129-137
Drug partitioning into lipid bilayers was studied by chromatography on liposomes and biomembranes immobilized in gel beads by freeze–thawing. The drug retention volume was expressed as a capacity f ...
Autor:
Farideh Beigi, Per Lundahl
Publikováno v:
Advanced Drug Delivery Reviews. 23:221-227
Liposomes are composed of lipid bilayers surrounding aqueous compartments. For attempts to predict drug absorption through cell membranes by use of a chromatographic model system, liposomes or biological membrane vesicles can be sterically immobilize