Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Farida S Akhtari"'
Autor:
Jasmine A. Mack, Adam Burkholder, Farida S. Akhtari, John S. House, Ulla Sovio, Gordon C.S. Smith, Charles P. Schmitt, David C. Fargo, Janet E. Hall, Alison A. Motsinger-Reif
Publikováno v:
HGG Advances, Vol 6, Iss 1, Pp 100385- (2025)
Summary: Genetic factors related to pregnancy-related traits are understudied, especially in ancestrally diverse cohorts. To assess maternal contributions to hypertensive disorders of pregnancy (HDP), we performed a multi-ancestry genome-wide associa
Externí odkaz:
https://doaj.org/article/fe214fe7ea2846c3ac4af17ffeb4d26e
Autor:
John S. House, Joseph H. Breeyear, Farida S. Akhtari, Violet Evans, John B. Buse, James Hempe, Alessandro Doria, Josyf C. Mychaleckyi, Vivian Fonseca, Mengyao Shi, Changwei Li, Shuqian Liu, Tanika N. Kelly, Daniel Rotroff, Alison A. Motsinger-Reif
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionWe investigated the genetic determinants of variation in the hemoglobin glycation index (HGI), an emerging biomarker for the risk of diabetes complications.MethodsWe conducted a genome-wide association study (GWAS) for HGI in the Action t
Externí odkaz:
https://doaj.org/article/40ca2401c4bc4845ae5fe4fd8f5dab9e
Autor:
Eunice Y. Lee, Wonson Choi, Adam B. Burkholder, Lalith Perera, Jasmine A. Mack, Frederick W. Miller, Michael B. Fessler, Donald N. Cook, Peer W. F. Karmaus, Hideki Nakano, Stavros Garantziotis, Jennifer H. Madenspacher, John S. House, Farida S. Akhtari, Charles S. Schmitt, David C. Fargo, Janet E. Hall, Alison A. Motsinger-Reif
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Asthma is a chronic disease of the airways that impairs normal breathing. The etiology of asthma is complex and involves multiple factors, including the environment and genetics, especially the distinct genetic architecture associated w
Externí odkaz:
https://doaj.org/article/b4c25f7994204ed68ceec9b548045815
Autor:
Montserrat Ayala-Ramirez, Nathaniel MacNell, Lucy E. McNamee, John A. McGrath, Farida S. Akhtari, Matthew D. Curry, Askia K. Dunnon, Michael B. Fessler, Stavros Garantziotis, Christine G. Parks, David C. Fargo, Charles P. Schmitt, Alison A. Motsinger-Reif, Janet E. Hall, Frederick W. Miller, Shepherd H. Schurman
Publikováno v:
Environment International, Vol 171, Iss , Pp 107687- (2023)
Background: Concentrated animal feeding operations (CAFOs) are a source of environmental pollution and have been associated with a variety of health outcomes. Immune-mediated diseases (IMD) are characterized by dysregulation of the normal immune resp
Externí odkaz:
https://doaj.org/article/6fd750625d1e400ea420cb3e832fe69d
Autor:
George W. Small, Farida S. Akhtari, Adrian J. Green, Tammy M. Havener, Michael Sikes, Julia Quintanhila, Ricardo D. Gonzalez, David M. Reif, Alison A. Motsinger-Reif, Howard L. McLeod, Tim Wiltshire
Publikováno v:
Cells, Vol 12, Iss 12, p 1574 (2023)
Monoclonal antibody (mAb) therapy directed against CD20 is an important tool in the treatment of B cell disorders. However, variable patient response and acquired resistance remain important clinical challenges. To identify genetic factors that may i
Externí odkaz:
https://doaj.org/article/fc45090c563c425fbc7ecb27e7e70be1
Autor:
Ricardo D. Gonzalez, George W. Small, Adrian J. Green, Farida S. Akhtari, Tammy M. Havener, Julia C. F. Quintanilha, Amber B. Cipriani, David M. Reif, Howard L. McLeod, Alison A. Motsinger-Reif, Tim Wiltshire
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 726 (2023)
Temozolomide (TMZ) chemotherapy is an important tool in the treatment of glioma brain tumors. However, variable patient response and chemo-resistance remain exceptionally challenging. Our previous genome-wide association study (GWAS) identified a sug
Externí odkaz:
https://doaj.org/article/57e65b5154c4450e9438e8a07a74bd2b
Autor:
Ricardo D. Gonzalez, George W. Small, Adrian J. Green, Farida S. Akhtari, Alison A. Motsinger-Reif, Julia C. F. Quintanilha, Tammy M. Havener, David M. Reif, Howard L. McLeod, Tim Wiltshire
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 757 (2023)
Oxaliplatin (OXAL) is a commonly used chemotherapy for treating colorectal cancer (CRC). A recent genome wide association study (GWAS) showed that a genetic variant (rs11006706) in the lncRNA gene MKX-AS1 and partnered sense gene MKX could impact the
Externí odkaz:
https://doaj.org/article/8aa3c245cb8d4f288b8d1ffcb9ff9422
Autor:
Farida S Akhtari, Adrian J Green, George W Small, Tammy M Havener, John S House, Kyle R Roell, David M Reif, Howard L McLeod, Timothy Wiltshire, Alison A Motsinger-Reif
Publikováno v:
PLoS Genetics, Vol 17, Iss 8, p e1009732 (2021)
Cancer patients exhibit a broad range of inter-individual variability in response and toxicity to widely used anticancer drugs, and genetic variation is a major contributor to this variability. To identify new genes that influence the response of 44
Externí odkaz:
https://doaj.org/article/f1416aa594d345ff9d7fa52334c49271
Autor:
Wiltshire, George W. Small, Farida S. Akhtari, Adrian J. Green, Tammy M. Havener, Michael Sikes, Julia Quintanhila, Ricardo D. Gonzalez, David M. Reif, Alison A. Motsinger-Reif, Howard L. McLeod, Tim
Publikováno v:
Cells; Volume 12; Issue 12; Pages: 1574
Monoclonal antibody (mAb) therapy directed against CD20 is an important tool in the treatment of B cell disorders. However, variable patient response and acquired resistance remain important clinical challenges. To identify genetic factors that may i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::60218ec289bf97ce7c7fd0873c0f1f70
Autor:
Farida S. Akhtari, Tammy M. Havener, Masahide Fukudo, John R. Jack, Howard L. McLeod, Tim Wiltshire, Alison A. Motsinger-Reif
Publikováno v:
PeerJ, Vol 6, p e5691 (2018)
Various studies have shown that people of Eurasian origin contain traces of DNA inherited from interbreeding with Neanderthals. Recent studies have demonstrated that these Neanderthal variants influence a range of clinically important traits and dise
Externí odkaz:
https://doaj.org/article/e8418042739a49c09c701da19bdde99b