Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Farid Sari-Sarraf"'
Autor:
Ye Wang, Morvarid Mohseni, Angelo Grauel, Javier Estrada Diez, Wei Guan, Simon Liang, Jiyoung Elizabeth Choi, Minying Pu, Dongshu Chen, Tyler Laszewski, Stephanie Schwartz, Jane Gu, Leandra Mansur, Tyler Burks, Lauren Brodeur, Roberto Velazquez, Steve Kovats, Bhavesh Pant, Giri Buruzula, Emily Deng, Julie T. Chen, Farid Sari-Sarraf, Christina Dornelas, Malini Varadarajan, Haiyan Yu, Chen Liu, Joanne Lim, Huai-Xiang Hao, Xiaomo Jiang, Anthony Malamas, Matthew J. LaMarche, Felipe Correa Geyer, Margaret McLaughlin, Carlotta Costa, Joel Wagner, David Ruddy, Pushpa Jayaraman, Nathaniel D. Kirkpatrick, Pu Zhang, Oleg Iartchouk, Kimberly Aardalen, Viviana Cremasco, Glenn Dranoff, Jeffrey A. Engelman, Serena Silver, Hongyun Wang, William D. Hastings, Silvia Goldoni
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-23 (2021)
Abstract SHP2 is a ubiquitous tyrosine phosphatase involved in regulating both tumor and immune cell signaling. In this study, we discovered a novel immune modulatory function of SHP2. Targeting this protein with allosteric SHP2 inhibitors promoted a
Externí odkaz:
https://doaj.org/article/aeca1d5b6b344aeabcc21b726ae4f617
In vivo imaging with fluorescent smart probes to assess treatment strategies for acute pancreatitis.
Autor:
Abhiruchi Agarwal, Andreas Boettcher, Rainer Kneuer, Farid Sari-Sarraf, Adriana Donovan, Julian Woelcke, Oliver Simic, Trixi Brandl, Thomas Krucker
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55959 (2013)
BACKGROUND AND AIMS: Endoprotease activation is a key step in acute pancreatitis and early inhibition of these enzymes may protect from organ damage. In vivo models commonly used to evaluate protease inhibitors require animal sacrifice and therefore
Externí odkaz:
https://doaj.org/article/685a8db557fa415b8d07c6ac5aa241bb
Autor:
Abhiruchi Agarwal, Andreas Boettcher, Rainer Kneuer, Farid Sari-Sarraf, Adriana Donovan, Julian Woelcke, Oliver Simic, Trixi Brandl, Thomas Krucker
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/2cf0564e4d7e42d9aa43d1aeb843175c
Autor:
Farid Sari-Sarraf, Gillis R. Otten, Timothy Pepini, Thomas Carsillo, Carlo Iavarone, Jeffrey B. Ulmer, Dong Yu, Alicia L. Carlson, Giulietta Maruggi, Jason C. Debasitis, Katrin Ramsauer, Anne-Marie Pulichino, Andrew Geall
Publikováno v:
The Journal of Immunology. 198:4012-4024
RNA-based vaccines have recently emerged as a promising alternative to the use of DNA-based and viral vector vaccines, in part because of the potential to simplify how vaccines are made and facilitate a rapid response to newly emerging infections. SA
Autor:
Farid Sari-Sarraf, Kerri J. Grove, John W. Fathman, Andrea K. Pomerantz, Patrick J Rudewicz, Liliana Pedro, Thomas Krucker
Publikováno v:
Expert opinion on drug discovery. 14(2)
Single-cell imaging-based assays are an area of active and growing investment in drug discovery and development. This approach offers researchers the capability to interrogate rare subpopulations of cells with minimal sample consumption and multiplex
Autor:
Didier Laurent, John S. Gounarides, Thomas Edward Hughes, Xue Li, Farid Sari-Sarraf, S. Renee Commerford, Erik C. Rocheford, Tara L. Mullarkey, Suzanne E. Dorfman, Erica A. Hirsch
Publikováno v:
Obesity. 17:1200-1207
Dietary trans-fatty acids are associated with increased risk of cardiovascular disease and have been implicated in the incidence of obesity and type 2 diabetes mellitus (T2DM). It is established that high-fat saturated diets, relative to low-fat diet
Publikováno v:
Magnetic Resonance Materials in Physics, Biology and Medicine. 21:291-297
To assess the feasibility of utilizing dynamic contrast enhanced (DCE)-MRI for depicting the effects of N G-nitro-l-arginine methylester (l-NAME), a nitric oxide synthase (NOS) inhibitor, on glomerular filtration rate (GFR) in rats. Since Gd-DTPA is
Targeting of the Antivascular Drug Combretastatin to Irradiated Tumors Results in Tumor Growth Delay
Autor:
Mohammad F. Kiani, George C. Wood, Christopher B. Pattillo, Farid Sari-Sarraf, Bob M. Moore, Ramakrishna Nallamothu
Publikováno v:
Pharmaceutical Research. 22:1117-1120
The aim of the study is to evaluate the effects of targeting the antivascular drug combretastatin to irradiated mouse melanomas.Combretastatin was incorporated into liposomes with surfaces modified by the addition of cyclo(Arg-Gly-Asp-D-Phe-Cys) (RGD
Autor:
Xue Li, Erik C. Rocheford, S. Renee Commerford, Thomas Edward Hughes, John S. Gounarides, Erica A. Hirsch, Farid Sari-Sarraf, Suzanne E. Dorfman, Didier Laurent, Tara L. Mullarkey
Publikováno v:
Obesity. 17:1474-1474
Publikováno v:
MAGMA: Magnetic Resonance Materials in Physics, Biology & Medicine; Aug2008, Vol. 21 Issue 4, p291-297, 7p