Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Farid N, Faruqu"'
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 7, Pp 419-433 (2020)
Abstract Stem cell‐derived exosomes have been identified as novel cell‐free therapeutics for regenerative medicine. Three‐dimensional (3D) culture of stem cells were reported to improve their “stemness” and therapeutic efficacy. This work f
Externí odkaz:
https://doaj.org/article/8ba88eee051c4e00896faef264a24099
Autor:
Sim Lai Tung, Giorgia Fanelli, Robert Ian Matthews, Jordan Bazoer, Marilena Letizia, Gema Vizcay-Barrena, Farid N. Faruqu, Christina Philippeos, Rosalind Hannen, Khuloud T. Al-Jamal, Giovanna Lombardi, Lesley Ann Smyth
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Regulatory T cells (Tregs) are a subpopulation of CD4+ T cells with a fundamental role in maintaining immune homeostasis and inhibiting unwanted immune responses using several different mechanisms. Recently, the intercellular transfer of molecules be
Externí odkaz:
https://doaj.org/article/773536993a454f9fa1748b7fa66718d4
Autor:
Lizhou Xu, Farid N. Faruqu, Revadee Liam-or, Omar Abu Abed, Danyang Li, Kerrie Venner, Rachel J Errington, Huw Summers, Julie Tzu-Wen Wang, Khuloud T. Al-Jamal
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Exosomes (Exo)-based therapy holds promise for treatment of lethal pancreatic cancer (PC). Limited understanding of key factors affecting Exo uptake in PC cells restricts better design of Exo-based therapy. This work aims to study the uptake properti
Externí odkaz:
https://doaj.org/article/5a114bfad1134fcfa1208ab9533b7031
Publikováno v:
FASEB BioAdvances
FASEB BioAdvances, Vol 2, Iss 7, Pp 419-433 (2020)
FASEB BioAdvances, Vol 2, Iss 7, Pp 419-433 (2020)
Stem cell‐derived exosomes have been identified as novel cell‐free therapeutics for regenerative medicine. Three‐dimensional (3D) culture of stem cells were reported to improve their “stemness” and therapeutic efficacy. This work focused on
Autor:
Azalea A, Khan, Francis, Man, Farid N, Faruqu, Jana, Kim, Fahad, Al-Salemee, Amaia, Carrascal-Miniño, Alessia, Volpe, Revadee, Liam-Or, Paul, Simpson, Gilbert O, Fruhwirth, Khuloud T, Al-Jamal, Rafael, T M de Rosales
Publikováno v:
Bioconjugate chemistry. 33(3)
Exosomes or small extracellular vesicles (sEVs) are increasingly gaining attention for their potential as drug delivery systems and biomarkers of disease. Therefore, it is important to understand their
Autor:
Amer F. Saleh, Janusz Rak, Elisa Lázaro-Ibáñez, Khuloud T. Al-Jamal, Farid N. Faruqu, Niek Dekker, Julie Tzu-Wen Wang, Andreia M. Silva
Publikováno v:
ACS Nano
The ability to track extracellular vesicles (EVs) in vivo without influencing their biodistribution is a key requirement for their successful development as drug delivery vehicles and therapeutic agents. Here, we evaluated the effect of five differen
Publikováno v:
The FASEB Journal
Stem cell‐derived exosomes are emerging as novel and clinically relevant cell‐free therapeutics for regenerative therapy. This work focused on investigating the stimulation of fibroblasts by exosomes derived from umbilical cord‐derived mesenchy
Autor:
Farid N. Faruqu, Prabhanjan S Giram, Priyanka P. Rade, Hend Mohamed Abdel-Bar, Khuloud T. Al-Jamal, Baijayantimala Garnaik, Muhammad Akhtar, Shunping Han, Adam A. Walters, Julie Tzu-Wen Wang
Publikováno v:
Biomaterials science. 9(3)
Poly(lactic-co-glycolic acid) (PLGA) is the most commonly described biocompatible copolymer used in biomedical applications. In this work, a green synthetic approach based on the biocompatible zinc proline complex, as an initiator for PLGA synthesis,
Autor:
Rosalind F. Hannen, Khuloud T. Al-Jamal, Giorgia Fanelli, Giovanna Lombardi, Lesley A. Smyth, Christina Philippeos, Farid N. Faruqu, Jordan Bazoer, Gema Vizcay-Barrena, Marilena Letizia, Robert Ian Matthews, Sim L. Tung
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Regulatory T cells (Tregs) are a subpopulation of CD4+ T cells with a fundamental role in maintaining immune homeostasis and inhibiting unwanted immune responses using several different mechanisms. Recently, the intercellular transfer of molecules be
Autor:
Khuloud T. Al-Jamal, Farid N. Faruqu, Yau M. Lim, Paul Lavender, Kee Y. Lim, Revadee Liam-or, Adam A. Walters, Claire M. Wells, Lizhou Xu, Julie Tzu-Wen Wang, David J. Fear
Publikováno v:
Biomaterials. 264
With a dismal survival rate, pancreatic cancer (PC) remains one of the most aggressive and devastating malignancies, predominantly due to the absence of a valid biomarker for diagnosis and limited therapeutic options for advanced diseases. Exosomes (