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pro vyhledávání: '"Farid Dormishian"'
Autor:
Adam Sampson-Johannes, Ali Fattaey, Allan Balmain, Jenny Holt, Vivian Lee, Thomas Dubensky, Galila Kitzes, Wen Yan, Yuqiao Shen, Terry Hermiston, Josh Watanabe, Farid Dormishian, Lynda K Hawkins
Publikováno v:
Journal of Virology. 77:2640-2650
Mutants of human adenovirus 5 (Ad5) with enhanced oncolytic activity were isolated by using a procedure termed bioselection. Two mutants, ONYX-201 and ONYX-203, were plaque purified from a pool of randomly mutagenized Ad5 that was repeatedly passaged