Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Farid Benayoud"'
Autor:
Kunihiko Kanatsu, Yoshinori Takahashi, Tetsuya Sakaguchi, Dae-Shik Kim, Miki Murota, Mingde Shan, Kazuki Fukami, Wataru Itano, Kenji Kikuta, Hikaru Yoshimura, Toshiki Kurokawa, Yuko Nagayama, Rena Ishikawa, Ryo Dairiki, Zhi Zhou, Kristen Sanders, Jacob Stupalski, So Yasui, Diana Liu, Farid Benayoud, Hui Fang, Enxuan Jing, Makoto Ogo, Francis G. Fang, John Wang, Hyeong-wook Choi
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 36, Iss 1, Pp 102404- (2025)
Antisense oligonucleotides (ASOs) are an important class of therapeutics to treat genetic diseases, and expansion of this modality to neurodegenerative disorders has been an active area of research. To realize chronic administration of ASO therapeuti
Externí odkaz:
https://doaj.org/article/48fa025010654763a422d4a52be32434
Autor:
W. David Hong, Paul M. O’Neill, Mark J. Taylor, Joseph D. Turner, Stephen A. Ward, Fabian Gusovsky, Farid Benayoud, Nao Shibuguchi, Dixit Girish, Francis Gerard Fang, Ravi Kumar Talabhakthla, Anand Vaddi, Chiranjeevi Challa, Karri Satya Ammi Reddy, Vijay Kalla, Sugandham Srinivasa Rao, Durga Mahesh Kumar Nagireddi, Jayesh Patel, Anil Shahaji Khile
Publikováno v:
Organic Process Research & Development. 27:42-53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf0cebc4b28857e48d61afccfffcf4ea
https://doi.org/10.1021/acs.oprd.2c00167
https://doi.org/10.1021/acs.oprd.2c00167
Autor:
Farid Benayoud, Masayuki Omori, Yuichi Suzuki, Arani Chanda, Kazunori Wakasugi, Yuzo Watanabe, Akio Kayano, Paschalis Dimopoulos, Yoichi Kita, Kunitoshi Takeda, Toshihiko Kaneko, Mitsuo Nagai, Noboru Yamamoto, Takafumi Motoki, Kazuhiro Yoshizawa, Christopher Neil Farthing, Lily Lu, Matthew J. Schnaderbeck, Khan Afzal, Tasuku Ishida, Huiming Zhang, Mamoru Takaishi, Markus Bracke, Branko Mitasev, Dae-Shik Kim, Francis G. Fang, Adrian Hall
Publikováno v:
Organic Process Research & Development. 26:804-816
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb5e8d3db93d6da5adb84ced4755f7b9
https://doi.org/10.1021/acs.oprd.1c00223
https://doi.org/10.1021/acs.oprd.1c00223
Autor:
Dae-Shik Kim, Kazuhiro Yoshizawa, Branko Mitasev, Schnaderbeck, Matthew, Huiming Zhang, Masayuki Omori, Akio Kayano, Mitsuo Nagai, Kazunori Wakasugi, Yuzo Watanabe, Farid Benayoud, Yuichi Suzuki, Takafumi Motoki, Toshihiko Kaneko, Mamoru Takaishi, Tasuku Ishida, Kunitoshi Takeda, Yoichi Kita, Noboru Yamamoto, Afzal Khan
Publikováno v:
Organic Process Research & Development; 3/18/2022, Vol. 26 Issue 3, p804-816, 13p
AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis
Autor:
Paul M. O'Neill, Edward W. Tate, W. David Hong, Adam P. Roberts, Marc P. Hübner, Peter J. H. Webborn, Mark J. Taylor, Alexandra Ehrens, Stefan J. Frohberger, Dominique Struever, John Archer, Farid Benayoud, Joseph D. Turner, Rachel H. Clare, Achim Hoerauf, Stefan Kavanagh, Fabian Gusovsky, Andrew Steven, Neil G. Berry, Kelly L. Johnston, Ghaith Aljayyoussi, Andrew Cassidy, Remigiusz A. Serwa, Suet C. Leung, Janet Hemingway, Alasdair T. M. Hubbard, Gemma L. Nixon, Amy Siu, Stephen A. Ward, Emma A Murphy, Louise Ford, Li Qie, Motohiro Shiotani, Darren A. N. Cook
Publikováno v:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Onchocerciasis and lymphatic filariasis are two neglected tropical diseases that together affect ∼157 million people and inflict severe disability. Both diseases are caused by parasitic filarial nematodes with elimination efforts constrained by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d971c5d526af7ac9de5fb24d20f2893d
Autor:
W David, Hong, Farid, Benayoud, Gemma L, Nixon, Louise, Ford, Kelly L, Johnston, Rachel H, Clare, Andrew, Cassidy, Darren A N, Cook, Amy, Siu, Motohiro, Shiotani, Peter J H, Webborn, Stefan, Kavanagh, Ghaith, Aljayyoussi, Emma, Murphy, Andrew, Steven, John, Archer, Dominique, Struever, Stefan J, Frohberger, Alexandra, Ehrens, Marc P, Hübner, Achim, Hoerauf, Adam P, Roberts, Alasdair T M, Hubbard, Edward W, Tate, Remigiusz A, Serwa, Suet C, Leung, Li, Qie, Neil G, Berry, Fabian, Gusovsky, Janet, Hemingway, Joseph D, Turner, Mark J, Taylor, Stephen A, Ward, Paul M, O'Neill
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis) are neglected tropical diseases that cause severe disability and affect more than 157 million people globally. Current control efforts are hindered by the lack of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a67afcb9d9f3a9d55bf8c9a97e46c9a1
https://pubmed.ncbi.nlm.nih.gov/30617067
https://pubmed.ncbi.nlm.nih.gov/30617067
Autor:
Yongbo Hu, James Cutter, Naoki Asai, Taichi Abe, Hyeong-Wook Choi, Teiji Takigawa, Taiju Nakamura, Thomas Noland, Masanori Mizuno, Atsushi Endo, Marc Pesant, Michael D. Lewis, Takao Omae, Bryan M. Lewis, Kazuhiro Yoshizawa, Francis G. Fang, Tomohiro Watanabe, Shawn McKenna, William J. Christ, Naoki Ozeki, Brian Austad, Gordon D. Wilkie, Hirofumi Kuroda, Trevor Lee Calkins, Manabu Kubota, Akio Kayano, Yumi Asai, John D. Orr, Matthew J. Schnaderbeck, Farid Benayoud, Yuki Komatsu, Robert Costanzo, Silvio Campagna, Taeko Suzuki, Charles E. Chase, Yuichi Kimoto
Publikováno v:
Synlett. 24:327-332
Multikilogram manufacturing process of the Halaven® C14–C35 fragment is described. The synthesis features convergent assembly of subunits by iterative asymmetric Ni/Cr-mediated coupling executed in fixed equipment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c0b6f0e62a97eb1ab238ef7f2117e0
https://doi.org/10.1055/s-0032-1317920
https://doi.org/10.1055/s-0032-1317920
Publikováno v:
Drug Metabolism and Pharmacokinetics. 33:S83
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ea5becc9630006b0589809659aed607
https://doi.org/10.1016/j.dmpk.2017.11.273
https://doi.org/10.1016/j.dmpk.2017.11.273
Publikováno v:
The Journal of Organic Chemistry. 70:9382-9398
[Reaction: see text]. Two efficient routes to the C1-C22 subunit of halichondrin B are described. The cage ketal 7, which contains 11 asymmetric centers embedded within the ABCDEF-ring framework, was assembled from (+)-conduritol E (27) in 18 steps a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfc1feee0e3359efef19c7001f6ecdc
https://doi.org/10.1021/jo051479m
https://doi.org/10.1021/jo051479m
Autor:
Ahmed Abouabdellah, Danièle Bonnet-Delpon, Olivier Boutaud, Farid Benayoud, Cyrille Richard, Jean-Pierre Bégué, Francis Schuber, Danielle Levasseur
Publikováno v:
Tetrahedron Letters. 41:6367-6370
Trifluoromethyl ketones 1 and 2, have been prepared from trisnorsqualene aldehyde 3. These compounds and their corresponding alcohols 4 and 7 have been found to be good inhibitors of the biosynthesis of cholesterol in HepG2 cells. The inhibition is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dee028306bbca6f155fdbb28d93ebe9e
https://doi.org/10.1016/s0040-4039(00)01066-2
https://doi.org/10.1016/s0040-4039(00)01066-2