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pro vyhledávání: '"Fariba Khanshan"'
Autor:
Sun Loo, Rupa Narayan, Mikael L. Rinne, Mika Kontro, Andrew M. Stein, Oliver G. Ottmann, Haiying Sun, Norbert Vey, Jeroen Janssen, Guillermo Garcia-Manero, Steve Knapper, Kimmo Porkka, Sebastian Scholl, Jordi Esteve, Fariba Khanshan, Andrew H. Wei, Elie Traer, Uma Borate, Purushotham Naidu, Natalia Tovar, Martin Wermke, Anisa Mohammed, Na Zhang, Andrew M. Brunner, Siyan Xu, Serena Liao
Publikováno v:
Blood. 136:40-42
Background: Sabatolimab (MBG453) is a high-affinity, humanized, IgG4 (S228P) antibody targeting TIM-3, an inhibitory receptor expressed on multiple immune cells and on leukemic stem/progenitor cells and blasts, but not on normal hematopoietic stem ce