Heparanase expression and activity are increased in platelets during clinical sepsis.

Autor: Eustes AS; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA.; Department of Pathology, University of Utah, Salt Lake City, Utah, USA.; Hospitals and Clinics Pathology, Internal Medicine, University of Iowa, Iowa City, Iowa, USA., Campbell RA; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA., Middleton EA; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA., Tolley ND; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA., Manne BK; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA., Montenont E; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA., Rowley JW; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA., Krauel K; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA.; Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Freiburg, Germany., Blair A; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA., Guo L; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA., Kosaka Y; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA., Medeiros-de-Moraes IM; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (Fiocruz, Rio de Janeiro and Manaus, Brazil., Lacerda M; Fundacao de Medicina Tropical - Dr. Heitor Vieira Dourado (FMT-HVD) and Fiocruz Manaus, Manaus, Brazil., Hottz ED; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA.; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (Fiocruz, Rio de Janeiro and Manaus, Brazil.; Immunothrombosis Laboratory, Department of Biochemistry, Federal University of Juiz de Fora, Juiz de Fora, Brazil.; Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, Brazil., Neto HCF; Fundacao de Medicina Tropical - Dr. Heitor Vieira Dourado (FMT-HVD) and Fiocruz Manaus, Manaus, Brazil., Zimmerman GA; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA., Weyrich AS; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA.; Department of Pathology, University of Utah, Salt Lake City, Utah, USA., Petrey A; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA.; Department of Pathology, University of Utah, Salt Lake City, Utah, USA., Rondina MT; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA.; Department of Pathology, University of Utah, Salt Lake City, Utah, USA.; Department of Internal Medicine and GRECC, George E. Wahlen VAMC, Salt Lake City, Utah, USA.

Publikováno v: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2021 May; Vol. 19 (5), pp. 1319-1330. Date of Electronic Publication: 2021 Mar 11.