Výsledky vyhledávání - "Farheen BadrealamKhan"

Design, Synthesis, and Structure–Activity Relationships of 1,2,3-Triazole Benzenesulfonamides as New Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors

Autor: Ke Ding, Jinfeng Luo, Cai-Hong Yun, Jianzhang Yang, Yanhui Huang, Zhengchao Tu, Marthandam Asokan Shibu, Lulu Kong, Xiaoyun Lu, Chih Yang Huang, Farheen BadrealamKhan

Publikováno v: Journal of Medicinal Chemistry. 63:2114-2130

ZAK is a new promising target for discovery of drugs with activity against antihypertrophic cardiomyopathy (HCM). A series of 1,2,3-triazole benzenesulfonamides were designed and synthesized as selective ZAK inhibitors. One of these compounds, 6p bin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f23ac5b1a579fca94b9bd9b4dfffdd
https://doi.org/10.1021/acs.jmedchem.9b00664

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