Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Farhang Alem"'
Autor:
Farhang Alem, Ashwini Brahms, Kaori Tarasaki, Samson Omole, Kylene Kehn-Hall, Connie S. Schmaljohn, Sina Bavari, Shinji Makino, Ramin M. Hakami
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
The mosquito-borne Rift Valley fever virus (RVFV) from the Phenuiviridae family is a single-stranded RNA virus that causes the re-emerging zoonotic disease Rift Valley fever (RVF). Classified as a Category A agent by the NIH, RVFV infection can cause
Externí odkaz:
https://doaj.org/article/bf372d6714b84a879e31760e2a0f982d
Autor:
Esra Oktay, Farhang Alem, Keziah Hernandez, Michael Girgis, Christopher Green, Divita Mathur, Igor L. Medintz, Aarthi Narayanan, Remi Veneziano
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
A DNA origami nanoparticle-based vaccine against SARS-Cov-2 co-delivers viral RBD antigen and CpG adjuvant and elicits a robust protective immunity against the virus in a mouse model.
Externí odkaz:
https://doaj.org/article/c458177b8dfe441594f04cc9f32b63aa
Autor:
Sirle Saul, Marwah Karim, Luca Ghita, Pei-Tzu Huang, Winston Chiu, Verónica Durán, Chieh-Wen Lo, Sathish Kumar, Nishank Bhalla, Pieter Leyssen, Farhang Alem, Niloufar A. Boghdeh, Do H.N. Tran, Courtney A. Cohen, Jacquelyn A. Brown, Kathleen E. Huie, Courtney Tindle, Mamdouh Sibai, Chengjin Ye, Ahmed Magdy Khalil, Kevin Chiem, Luis Martinez-Sobrido, John M. Dye, Benjamin A. Pinsky, Pradipta Ghosh, Soumita Das, David E. Solow-Cordero, Jing Jin, John P. Wikswo, Dirk Jochmans, Johan Neyts, Steven De Jonghe, Aarthi Narayanan, Shirit Einav
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
Targeting host factors exploited by multiple viruses could offer broad-spectrum solutions for pandemic preparedness. Seventeen candidates targeting diverse functions emerged in a screen of 4,413 compounds for SARS-CoV-2 inhibitors. We demonstrated th
Externí odkaz:
https://doaj.org/article/9cc9d935abdc4025aa6c81ab75a6d932
Autor:
Carol A. Anderson, Michael D. Barrera, Niloufar A. Boghdeh, Miata Smith, Farhang Alem, Aarthi Narayanan
Publikováno v:
Microorganisms, Vol 12, Iss 1, p 54 (2023)
Alphaviruses, belonging to the Togaviridae family, and bunyaviruses, belonging to the Paramyxoviridae family, are globally distributed and lack FDA-approved vaccines and therapeutics. The alphaviruses Venezuelan equine encephalitis virus (VEEV) and e
Externí odkaz:
https://doaj.org/article/cb7a8e009b614da98b4474863e5ffdd6
Publikováno v:
Pathogens, Vol 12, Iss 12, p 1404 (2023)
A striking feature of COVID-19 disease is the broad spectrum of risk factors associated with case severity, as well as the diversity of clinical manifestations. While no central agent has been able to explain the pathogenesis of SARS-CoV-2 infection,
Externí odkaz:
https://doaj.org/article/fbabfc1293754e9e8ed8a3fc1c2765d6
Autor:
Farhang Alem, Adeyemi A. Olanrewaju, Samson Omole, Heather E. Hobbs, Noor Ahsan, Graham Matulis, Christine A. Brantner, Weidong Zhou, Emanuel F. Petricoin, Lance A. Liotta, Massimo Caputi, Sina Bavari, Yuntao Wu, Fatah Kashanchi, Ramin M. Hakami
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-21 (2021)
Abstract Background Although multiple studies have demonstrated a role for exosomes during virus infections, our understanding of the mechanisms by which exosome exchange regulates immune response during viral infections and affects viral pathogenesi
Externí odkaz:
https://doaj.org/article/85cd8e89439e4ebb889297f399db2f87
Autor:
Carol Anderson, Haseebullah Baha, Niloufar Boghdeh, Michael Barrera, Farhang Alem, Aarthi Narayanan
Publikováno v:
Viruses, Vol 15, Iss 5, p 1163 (2023)
Zoonotic pathogens that are vector-transmitted have and continue to contribute to several emerging infections globally. In recent years, spillover events of such zoonotic pathogens have increased in frequency as a result of direct contact with livest
Externí odkaz:
https://doaj.org/article/ab959b49115c4cf2999088829bdc47ed
Autor:
Daniel O. Pinto, Sarah Al Sharif, Gifty Mensah, Maria Cowen, Pooja Khatkar, James Erickson, Heather Branscome, Thomas Lattanze, Catherine DeMarino, Farhang Alem, Ruben Magni, Weidong Zhou, Sandrine Alais, Hélène Dutartre, Nazira El-Hage, Renaud Mahieux, Lance A. Liotta, Fatah Kashanchi
Publikováno v:
Retrovirology, Vol 18, Iss 1, Pp 1-27 (2021)
Abstract Background The Human T-cell Lymphotropic Virus Type-1 (HTLV-1) is a blood-borne pathogen and etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL) and HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). HTLV-1 has curre
Externí odkaz:
https://doaj.org/article/4364e98badb6462b9f29686cdbb50650
Autor:
Niloufar A. Boghdeh, Brittany McGraw, Michael D. Barrera, Carol Anderson, Haseebullah Baha, Kenneth H. Risner, Ifedayo V. Ogungbe, Farhang Alem, Aarthi Narayanan
Publikováno v:
Viruses, Vol 15, Iss 3, p 655 (2023)
New World alphaviruses including Venezuelan Equine Encephalitis Virus (VEEV) and Eastern Equine Encephalitis Virus (EEEV) are mosquito-transmitted viruses that cause disease in humans and equines. There are currently no FDA-approved therapeutics or v
Externí odkaz:
https://doaj.org/article/0d60f3c8a9cf46b583124eb7ab3ea1de
Autor:
Niloufar A. Boghdeh, Kenneth H. Risner, Michael D. Barrera, Clayton M. Britt, David K. Schaffer, Farhang Alem, Jacquelyn A. Brown, John P. Wikswo, Aarthi Narayanan
Publikováno v:
Viruses, Vol 14, Iss 12, p 2799 (2022)
The blood brain barrier (BBB) is a multicellular microenvironment that plays an important role in regulating bidirectional transport to and from the central nervous system (CNS). Infections by many acutely infectious viruses such as alphaviruses and
Externí odkaz:
https://doaj.org/article/fe4563b4c86244a9a3719032e2a49db1