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A multi-ancestry genome-wide association study identifies novel candidate loci in the RARB gene associated with hypertensive disorders of pregnancy.

Autor: Mack JA; National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA; University of Cambridge, Department of Obstetrics and Gynaecology, Cambridge, UK, CB2 0SW., Burkholder A; National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA., Akhtari FS; National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA., House JS; National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA., Sovio U; University of Cambridge, Department of Obstetrics and Gynaecology, Cambridge, UK, CB2 0SW., Smith GCS; University of Cambridge, Department of Obstetrics and Gynaecology, Cambridge, UK, CB2 0SW., Schmitt CP; National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA., Fargo DC; National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA., Hall JE; National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA., Motsinger-Reif AA; National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA. Electronic address: alison.motsinger-reif@nih.gov.

Publikováno v: HGG advances [HGG Adv] 2024 Nov 22, pp. 100385. Date of Electronic Publication: 2024 Nov 22.

Gene-environment interactions within a precision environmental health framework.

Autor: Motsinger-Reif AA; Biostatistics and Computational Biology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, Durham, NC, USA. Electronic address: alison.motsinger-reif@nih.gov., Reif DM; Predictive Toxicology Branch, Division of Translational Toxicology, National Institute of Environmental Health Sciences, Durham, NC, USA., Akhtari FS; Biostatistics and Computational Biology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, Durham, NC, USA., House JS; Biostatistics and Computational Biology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, Durham, NC, USA., Campbell CR; Biostatistics and Computational Biology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, Durham, NC, USA., Messier KP; Biostatistics and Computational Biology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, Durham, NC, USA; Predictive Toxicology Branch, Division of Translational Toxicology, National Institute of Environmental Health Sciences, Durham, NC, USA., Fargo DC; Office of the Director, National Institute of Environmental Health Sciences, Durham, NC, USA., Bowen TA; Office of the Director, National Institute of Environmental Health Sciences, Durham, NC, USA., Nadadur SS; Exposure, Response, and Technology Branch, Division of Extramural Research and Training, National Institute of Environmental Health Sciences, Durham, NC, USA., Schmitt CP; Office of the Scientific Director, Office of Data Science, National Institute of Environmental Health Sciences, Durham, NC, USA., Pettibone KG; Program Analysis Branch, Division of Extramural Research and Training, National Institute of Environmental Health Sciences, Durham, NC, USA., Balshaw DM; Office of the Director, National Institute of Environmental Health Sciences, Durham, NC, USA; Division of Extramural Research and Training, National Institute of Environmental Health Sciences, Durham, NC, USA., Lawler CP; Genes, Environment, and Health Branch, Division of Extramural Research and Training, National Institute of Environmental Health Sciences, Durham, NC, USA., Newton SA; Office of Scientific Coordination, Planning and Evaluation, National Institute of Environmental Health Sciences, Durham, NC, USA., Collman GW; Office of the Director, National Institute of Environmental Health Sciences, Durham, NC, USA; Office of Scientific Coordination, Planning and Evaluation, National Institute of Environmental Health Sciences, Durham, NC, USA., Miller AK; Office of Scientific Coordination, Planning and Evaluation, National Institute of Environmental Health Sciences, Durham, NC, USA., Merrick BA; Mechanistic Toxicology Branch, Division of Translational Toxicology, National Institute of Environmental Health Sciences, Durham, NC, USA., Cui Y; Exposure, Response, and Technology Branch, Division of Extramural Research and Training, National Institute of Environmental Health Sciences, Durham, NC, USA., Anchang B; Biostatistics and Computational Biology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, Durham, NC, USA., Harmon QE; Epidemiology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, Durham, NC, USA., McAllister KA; Genes, Environment, and Health Branch, Division of Extramural Research and Training, National Institute of Environmental Health Sciences, Durham, NC, USA., Woychik R; Office of the Director, National Institute of Environmental Health Sciences, Durham, NC, USA.

Publikováno v: Cell genomics [Cell Genom] 2024 Jul 10; Vol. 4 (7), pp. 100591. Date of Electronic Publication: 2024 Jun 25.

Questionnaire-based exposome-wide association studies for common diseases in the Personalized Environment and Genes Study.

Autor: Lloyd D; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, NC, USA., House JS; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, NC, USA., Akhtari FS; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, NC, USA., Schmitt CP; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Durham, NC, USA., Fargo DC; Office of the Director, National Institute of Environmental Health Sciences, Durham, NC, USA., Scholl EH; Sciome LLC, Durham, NC, USA., Phillips J; Sciome LLC, Durham, NC, USA., Choksi S; Sciome LLC, Durham, NC, USA., Shah R; Sciome LLC, Durham, NC, USA., Hall JE; Clinical Research Branch, National Institute of Environmental Health Sciences, Durham, NC, USA., Motsinger-Reif AA; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, NC, USA.

Publikováno v: Exposome [Exposome] 2024 Feb 12; Vol. 4 (1), pp. osae002. Date of Electronic Publication: 2024 Feb 12 (Print Publication: 2024).