Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Fardokht A. Abulwerdi"'
Autor:
Catherine DeMarino, Maria Cowen, Anastasia Williams, Pooja Khatkar, Fardokht A. Abulwerdi, Lisa Henderson, Julia Denniss, Michelle L. Pleet, Delores R. Luttrell, Iosif Vaisman, Lance A. Liotta, Joseph Steiner, Stuart F. J. Le Grice, Avindra Nath, Fatah Kashanchi
Publikováno v:
Viruses, Vol 16, Iss 4, p 643 (2024)
Human immunodeficiency virus type 1 (HIV-1) infection can result in HIV-associated neurocognitive disorder (HAND), a spectrum of disorders characterized by neurological impairment and chronic inflammation. Combined antiretroviral therapy (cART) has e
Externí odkaz:
https://doaj.org/article/fa37b5ce3b4d4952af12868288bfeeab
Autor:
Pooja Khatkar, Gifty Mensah, Shangbo Ning, Maria Cowen, Yuriy Kim, Anastasia Williams, Fardokht A. Abulwerdi, Yunjie Zhao, Chen Zeng, Stuart F. J. Le Grice, Fatah Kashanchi
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 33 (2023)
The HIV-1 transactivator protein Tat interacts with the transactivation response element (TAR) at the three-nucleotide UCU bulge to facilitate the recruitment of transcription elongation factor-b (P-TEFb) and induce the transcription of the integrate
Externí odkaz:
https://doaj.org/article/16630d3bc2964e1d8a47b520074e38ee
Autor:
Dongping Wei, Qiang Zhang, Jason S. Schreiber, Leslie A. Parsels, Fardokht A. Abulwerdi, Tasneem Kausar, Theodore S. Lawrence, Yi Sun, Zaneta Nikolovska-Coleska, Meredith A. Morgan
Publikováno v:
Translational Oncology, Vol 8, Iss 1, Pp 47-54 (2015)
In order to identify targets whose inhibition may enhance the efficacy of chemoradiation in pancreatic cancer, we previously conducted an RNAi library screen of 8,800 genes. We identified Mcl-1 (myeloid cell leukemia-1), an anti-apoptotic member of t
Externí odkaz:
https://doaj.org/article/1288888f068744ae967ef7688a937d90
Autor:
John S. Schneekloth, Bruce A. Shapiro, Regan M. LeBlanc, Claudia Del Vecchio, Maryia Svirydava, Theodore K. Dayie, Julie Nyman, Lukasz T. Olenginski, Wojciech Kasprzak, Fardokht A. Abulwerdi, Brigit Shields, Andrew P. Longhini, Stefano Ginocchio, Stuart F. J. Le Grice, Joseph Ivanic
Publikováno v:
J Biomol Struct Dyn
Initiation of protein-primed (−) strand DNA synthesis in hepatitis B virus (HBV) requires interaction of the viral polymerase with a cis-acting regulatory signal, designated epsilon ([Formula: see text]), located at the 5′-end of its pre-genomic
Autor:
Mohan Pal, Lei Miao, Andrej Perdih, Jacob M. Carlson, Nurul H. Ansari, Yuting Yang, Zaneta Nikolovska-Coleska, Jennifer L. Meagher, Jeanne A. Stuckey, Chenzhong Liao, Karson J. Kump, Ahmed S.A. Mady, Fardokht A. Abulwerdi, May Khanna, Uttar K. Shrestha, Krishnapriya Chinnaswamy
Publikováno v:
J Med Chem
Anti-apoptotic Bcl-2 family proteins are overexpressed in a wide spectrum of cancers and have become well validated therapeutic targets. Cancer cells display survival dependence on individual or subsets of anti-apoptotic proteins that could be effect
Autor:
Farzad Fatehi, Reidun Twarock, Nikesh Patel, John S. Schneekloth, S.F.J. Le Grice, Fardokht A. Abulwerdi, Peter G. Stockley, Iain W. Manfield
RNA sequences/motifs dispersed across the pre-genomic copy of the Hepatitis B Virus genome regulate formation of nucleocapsidsin vitroin an epsilon/polymerase independent fashion. These multiple RNA Packaging Signals (PSs) form stem-loops presenting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca3569fef2c786420d695fc1fc5f5239
https://doi.org/10.1101/2021.08.10.455820
https://doi.org/10.1101/2021.08.10.455820
Autor:
Abeer A. Ageeli, Fardokht A. Abulwerdi, Hyeyeon Nam, Wenbo Xu, John S. Schneekloth, Michael Yonkunas, Nathan J. Baird, David L. Spector, Gayatri Arun, Theodore K. Dayie, Stuart F. J. Le Grice
Publikováno v:
ACS chemical biology. 14(2)
Metastasis-associated lung adenocarcinoma transcript 1 ( Malat1/ MALAT1, mouse/human), a highly conserved long noncoding (lnc) RNA, has been linked with several physiological processes, including the alternative splicing, nuclear organization, and ep
Autor:
Lei Miao, Fardokht A. Abulwerdi, May Khanna, Yuting Yang, Jennifer L. Meagher, Jacob M. Carlson, Mohan Pal, Karson J. Kump, Andrej Perdih, Zaneta Nikolovska-Coleska, Nurul H. Ansari, Ahmed A. Mady, Uttar K. Shrestha, Krishnapriya Chinnaswamy, Jeanne A. Stuckey, Chenzhong Liao
Publikováno v:
Cancer Research. 80:LB-226
Anti-apoptotic Bcl-2 family proteins are frequently overexpressed in various cancers and are established therapeutic targets. Cancer cells can either display dependence on individual or subsets of these pro-survival proteins, which gives therapeutic
Autor:
Naval Bajwa, Karson J. Kump, Zaneta Nikolovska-Coleska, Haian Fu, Sierrah M. Grigsby, Lei Miao, Chenzhong Liao, Fardokht A. Abulwerdi, Ahmed S.A. Mady, Andrej Perdih, Yuhong Du, Katherine L. Lev, Jeanne A. Stuckey
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Protein-protein interactions (PPIs) represent important and promising therapeutic targets that are associated with the regulation of various molecular pathways, particularly in cancer. Although they were once considered “undruggable,” the recent
Autor:
Christine M. Burrer, Fardokht A. Abulwerdi, Megan A. Peppenelli, Olesea Cojohari, Gary C. Chan, Zaneta Nikolovska-Coleska
Publikováno v:
Journal of Virology. 89:5739-5746
Herpesviruses, including human cytomegalovirus (HCMV), Epstein-Barr virus (EBV), and Kaposi’s sarcoma-associated herpesvirus, establish latency by modulating or mimicking antiapoptotic Bcl-2 proteins to promote survival of carrier cells. BH3 profil