Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Farbod Darvishian"'
Autor:
Veronica Davalos, Claudia D. Lovell, Richard Von Itter, Igor Dolgalev, Praveen Agrawal, Gillian Baptiste, David J. Kahler, Elena Sokolova, Sebastian Moran, Laia Piqué, Eleazar Vega-Saenz de Miera, Barbara Fontanals-Cirera, Alcida Karz, Aristotelis Tsirigos, Chi Yun, Farbod Darvishian, Heather C. Etchevers, Iman Osman, Manel Esteller, Markus Schober, Eva Hernando
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Melanocytes can de-differentiate into neural crest cell (NCC)- like states during metastatic melanoma progression. Here the authors compare DNA methylation profiles of NCCs and melanocytes, as well as primary and metastatic patient tissues and identi
Externí odkaz:
https://doaj.org/article/8185f7446ad34fda88510e094a1353e3
Autor:
Farbod Darvishian, Yinxiang Wu, Ugur Ozerdem, Jennifer Chun, Sylvia Adams, Amber Guth, Deborah Axelrod, Richard Shapiro, Andrea B. Troxel, Freya Schnabel, Daniel Roses
Publikováno v:
Breast, Vol 64, Iss , Pp 35-40 (2022)
Introduction: There is evidence that supports the association of dense tumor infiltrating lymphocyte (TILs) with an increased risk of ipsilateral recurrence in ductal carcinoma in situ (DCIS). However, the association of cellular composition of DCIS
Externí odkaz:
https://doaj.org/article/51d9f4b28bf645b88cca501e0a2c27ee
Autor:
Milad Ibrahim, Irineu Illa-Bochaca, Faisal Fa’ak, Kelsey R. Monson, Robert Ferguson, Chen Lyu, Eleazar Vega-Saenz de Miera, Paul Johannet, Margaret Chou, Justin Mastroianni, Farbod Darvishian, Tomas Kirchhoff, Judy Zhong, Michelle Krogsgaard, Iman Osman
Publikováno v:
Cancers, Vol 16, Iss 1, p 18 (2023)
Background: We previously reported a higher incidence of a pathogenic germline variant in the kinase insert domain receptor (KDR) in melanoma patients compared to the general population. Here, we dissect the impact of this genotype on melanoma tumor
Externí odkaz:
https://doaj.org/article/f4f83bbe8d0f4d60be195bd1f1e6eea9
Autor:
Tess V. Clendenen, Wenzhen Ge, Karen L. Koenig, Yelena Afanasyeva, Claudia Agnoli, Louise A. Brinton, Farbod Darvishian, Joanne F. Dorgan, A. Heather Eliassen, Roni T. Falk, Göran Hallmans, Susan E. Hankinson, Judith Hoffman-Bolton, Timothy J. Key, Vittorio Krogh, Hazel B. Nichols, Dale P. Sandler, Minouk J. Schoemaker, Patrick M. Sluss, Malin Sund, Anthony J. Swerdlow, Kala Visvanathan, Anne Zeleniuch-Jacquotte, Mengling Liu
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-12 (2019)
Abstract Background Models that accurately predict risk of breast cancer are needed to help younger women make decisions about when to begin screening. Premenopausal concentrations of circulating anti-Müllerian hormone (AMH), a biomarker of ovarian
Externí odkaz:
https://doaj.org/article/5173ace532a544d39c8c04eefe3f07c5
Publikováno v:
Archives of Plastic Surgery, Vol 42, Iss 02, Pp 261-263 (2015)
Externí odkaz:
https://doaj.org/article/6986f0a655a4418fae17e871ffd3174f
Autor:
Molly Yancovitz, Adam Litterman, Joanne Yoon, Elise Ng, Richard L Shapiro, Russell S Berman, Anna C Pavlick, Farbod Darvishian, Paul Christos, Madhu Mazumdar, Iman Osman, David Polsky
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29336 (2012)
The rationale for using small molecule inhibitors of oncogenic proteins as cancer therapies depends, at least in part, on the assumption that metastatic tumors are primarily clonal with respect to mutant oncogene. With the emergence of BRAF(V600E) as
Externí odkaz:
https://doaj.org/article/b5525cc056164b37b0b637ca0759c512
Autor:
Chanh Huynh, Laura Poliseno, Miguel F. Segura, Ratna Medicherla, Adele Haimovic, Silvia Menendez, Shulian Shang, Anna Pavlick, Yongzhao Shao, Farbod Darvishian, John F. Boylan, Iman Osman, Eva Hernando
Publikováno v:
PLoS ONE, Vol 6, Iss 11 (2011)
Externí odkaz:
https://doaj.org/article/dc1081e009b54ef385af8dca07316e3f
Autor:
Chanh Huynh, Laura Poliseno, Miguel F Segura, Ratna Medicherla, Adele Haimovic, Silvia Menendez, Shulian Shang, Anna Pavlick, Yongzhao Shao, Farbod Darvishian, John F Boylan, Iman Osman, Eva Hernando
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25264 (2011)
Several reports have demonstrated a role for aberrant NOTCH signaling in melanoma genesis and progression, prompting us to explore if targeting this pathway is a valid therapeutic approach against melanoma. We targeted NOTCH signaling using RO4929097
Externí odkaz:
https://doaj.org/article/9d30d0ca44aa4f2587ae02ce7501142d
Autor:
Lawrence H. Lin, Ivy Tran, Yiying Yang, Paolo Cotzia, Daniel Roses, Freya Schnabel, Farbod Darvishian, Matija Snuderl
Publikováno v:
Cancer Research. 83:P2-23
Background: Triple negative breast cancers (TNBC) are characterized by the absence of estrogen receptors, progesterone receptors, and HER2 receptors on immunohistochemical analysis (IHC). This subtype of breast cancer has been traditionally associate
Autor:
Eva Hernando, Iman Osman, Anna C. Pavlick, Richard L. Shapiro, Russell S. Berman, Farbod Darvishian, Douglas Hanniford, Avital Gaziel, Jan Zakrzewski, Amy E. Rose, Ilana Belitskaya-Lévy, Miguel F. Segura
Purpose: To identify a melanoma microRNA (miRNA) expression signature that is predictive of outcome and then evaluate its potential to improve risk stratification when added to the standard-of-care staging criteria.Experimental Design: Total RNA was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333f15fc0806382d3bc8b3c1731b1979
https://doi.org/10.1158/1078-0432.c.6518724.v1
https://doi.org/10.1158/1078-0432.c.6518724.v1