Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Farbod, Mahmoudinobar"'
Autor:
Dustin Britton, Michael Meleties, Chengliang Liu, Sihan Jia, Farbod Mahmoudinobar, P. Douglas Renfrew, Richard Bonneau, Jin Kim Montclare
Publikováno v:
Molecular Systems Design & Engineering. 8:217-226
Higher-order supramolecular assembly of a coiled-coil protein can be modulated by iterative tuning of its electrostatic potential.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca2e76556957b7e7d3e459aa267b405c
https://doi.org/10.1039/d2me00153e
https://doi.org/10.1039/d2me00153e
Autor:
Dustin Britton, Kamia Punia, Farbod Mahmoudinobar, Takuya Tada, Xunqing Jiang, P. Douglas Renfrew, Richard Bonneau, Nathaniel R. Landau, Xiang-Peng Kong, Jin Kim Montclare
Publikováno v:
Biochemical engineering journal. 187
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic since December 2019, and with it, a push for innovations in rapid testing and neutralizing antibody treatments in an effort to solve the spread and fatality of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f42b30d765c92b0288a5621a2a8019
https://pubmed.ncbi.nlm.nih.gov/36034180
https://pubmed.ncbi.nlm.nih.gov/36034180
Publikováno v:
The Journal of Physical Chemistry B. 125:1085-1097
Aggregation of amyloid-β (Aβ) proteins in the brain is a hallmark of Alzheimer's disease. This phenomenon can be promoted or inhibited by adding small molecules to the solution where Aβ is embedded. These molecules affect the ensemble of conformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff3c34ed26f9e62b8b91c004bee0556b
https://doi.org/10.1021/acs.jpcb.0c09617
https://doi.org/10.1021/acs.jpcb.0c09617
Publikováno v:
Current Opinion in Structural Biology. 63:97-105
Hydrogels are classic examples of biomaterials that have found its niche in biomedical and allied fields. Here, we describe examples of peptide-based and protein-based hydrogels with a focus on smart gels that respond to various stimuli including tem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affe775e4a75448f21eb0378cfa06e2a
https://doi.org/10.1016/j.sbi.2020.04.007
https://doi.org/10.1016/j.sbi.2020.04.007
Publikováno v:
Computer Physics Communications. 244:385-391
GRADE is an open-source software package that identifies clathrate hydrate structures given the atomic coordinates of oxygen atoms of water. These structures are commonly found in natural gases and they are relevant to understand antifreezing protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c89ba31fe0cf665ebee2d34740faa90
https://doi.org/10.1016/j.cpc.2019.06.004
https://doi.org/10.1016/j.cpc.2019.06.004
Publikováno v:
The journal of physical chemistry. B. 125(4)
Aggregation of amyloid-β (Aβ) proteins in the brain is a hallmark of Alzheimer's disease. This phenomenon can be promoted or inhibited by adding small molecules to the solution where Aβ is embedded. These molecules affect the ensemble of conformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::402a74e05107e23a30048d720bf7a076
https://pubmed.ncbi.nlm.nih.gov/33481611
https://pubmed.ncbi.nlm.nih.gov/33481611
Publikováno v:
Protein Engineering, Design and Selection
To combat the enduring and dangerous spread of COVID-19, many innovations to rapid diagnostics have been developed based on proteinprotein interactions of the SARS-CoV-2 spike and nucleocapsid proteins to increase testing accessibility. These antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df72018b5988b8b2c0fe82773d63ef9d
https://doi.org/10.1093/protein/gzab010
https://doi.org/10.1093/protein/gzab010
Autor:
Sharareh Jalali, Yanxing Yang, Farbod Mahmoudinobar, Shaneen M. Singh, Bradley L. Nilsson, Cristiano Dias
Publikováno v:
Journal of Molecular Liquids. 347:118283
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3bee10d77a0dc54ebe1b073e8ce9350
https://doi.org/10.1016/j.molliq.2021.118283
https://doi.org/10.1016/j.molliq.2021.118283
Publikováno v:
Journal of chemical theory and computation. 15(6)
Thermodynamic stabilities of amyloid fibrils remain mostly unknown due to experimental challenges. Here, we combine enhanced sampling methods to simulate all-atom models in explicit water in order to study the stability of nonpolar (Aβ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c979923cf1170725687b58fd97257b
https://pubmed.ncbi.nlm.nih.gov/31038946
https://pubmed.ncbi.nlm.nih.gov/31038946
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 83:1963-1972
Here, we provide insights into the thermodynamic properties of A β16-21 dissociation from an amyloid fibril using all-atom molecular dynamics simulations in explicit water. An umbrella sampling protocol is used to compute potentials of mean force (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0b12205ee34ee4351ae32924e86a9c7
https://doi.org/10.1002/prot.24875
https://doi.org/10.1002/prot.24875