Zobrazeno 1 - 10
of 261
pro vyhledávání: '"Faraz K"'
Autor:
Matvei Khoroshkin, Andrey Buyan, Martin Dodel, Albertas Navickas, Johnny Yu, Fathima Trejo, Anthony Doty, Rithvik Baratam, Shaopu Zhou, Sean B. Lee, Tanvi Joshi, Kristle Garcia, Benedict Choi, Sohit Miglani, Vishvak Subramanyam, Hailey Modi, Christopher Carpenter, Daniel Markett, M. Ryan Corces, Faraz K. Mardakheh, Ivan V. Kulakovskiy, Hani Goodarzi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract In our cells, a limited number of RNA binding proteins (RBPs) are responsible for all aspects of RNA metabolism across the entire transcriptome. To accomplish this, RBPs form regulatory units that act on specific target regulons. However, th
Externí odkaz:
https://doaj.org/article/e0a9c0d9b7a0471c8ee72df7e5f560df
Autor:
Marcos Moreno-Aguilera, Alba M Neher, Mónica B Mendoza, Martin Dodel, Faraz K Mardakheh, Raúl Ortiz, Carme Gallego
Publikováno v:
eLife, Vol 13 (2024)
Alternative RNA splicing is an essential and dynamic process in neuronal differentiation and synapse maturation, and dysregulation of this process has been associated with neurodegenerative diseases. Recent studies have revealed the importance of RNA
Externí odkaz:
https://doaj.org/article/0a67d3a9a53e4c80abaed323d63b145b
Autor:
Kathryn Davidson, Paul Grevitt, Maria F. Contreras-Gerenas, Katherine S. Bridge, Miguel Hermida, Kunal M. Shah, Faraz K. Mardakheh, Mark Stubbs, Rosemary Burke, Pedro Casado, Pedro R. Cutillas, Sarah A. Martin, Tyson V. Sharp
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-10 (2021)
Abstract An early event in lung oncogenesis is loss of the tumour suppressor gene LIMD1 (LIM domains containing 1); this encodes a scaffold protein, which suppresses tumorigenesis via a number of different mechanisms. Approximately 45% of non-small c
Externí odkaz:
https://doaj.org/article/006a5cc989ef440e83fa93a4ded65708
Autor:
Maria Dermit, Faraz K. Mardakheh
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100462- (2021)
Summary: Actin-rich protrusions are membrane extensions generated by actin polymerization that drive mesenchymal-like cell migration. Characterization of protrusions proteome is crucial for understanding their function. We present a complete step-by-
Externí odkaz:
https://doaj.org/article/52f1153d0c784b16bfda1422a13f12d5
Autor:
Rachael Natrajan, Heba Sailem, Faraz K Mardakheh, Mar Arias Garcia, Christopher J Tape, Mitch Dowsett, Chris Bakal, Yinyin Yuan
Publikováno v:
PLoS Medicine, Vol 13, Iss 2, p e1001961 (2016)
BackgroundThe intra-tumor diversity of cancer cells is under intense investigation; however, little is known about the heterogeneity of the tumor microenvironment that is key to cancer progression and evolution. We aimed to assess the degree of micro
Externí odkaz:
https://doaj.org/article/35ff3f6e44eb4dfeadeb84a0e001c74e
Autor:
Sandra Kümper, Faraz K Mardakheh, Afshan McCarthy, Maggie Yeo, Gordon W Stamp, Angela Paul, Jonathan Worboys, Amine Sadok, Claus Jørgensen, Sabrina Guichard, Christopher J Marshall
Publikováno v:
eLife, Vol 5 (2016)
Rho-associated kinases 1 and 2 (ROCK1/2) are Rho-GTPase effectors that control key aspects of the actin cytoskeleton, but their role in proliferation and cancer initiation or progression is not known. Here, we provide evidence that ROCK1 and ROCK2 ac
Externí odkaz:
https://doaj.org/article/25094a7f56904648b7ef07430fa65e3d
Autor:
Chokshi, Niraliben B.K., Karmakar, Bratati, Pathan, Shahab K., Joshi, Vikram, Gohel, Dhwani M., Coulshed, David S., Negishi, Kazuaki, Pathan, Faraz K.
Publikováno v:
In Heart, Lung and Circulation April 2023 32(4):441-453
Autor:
Khoroshkin, Matvei, Buyan, Andrey, Dodel, Martin, Navickas, Albertas, Yu, Johnny, Trejo, Fathima, Doty, Anthony, Baratam, Rithvik, Zhou, Shaopu, Lee, Sean B., Joshi, Tanvi, Garcia, Kristle, Choi, Benedict, Miglani, Sohit, Subramanyam, Vishvak, Modi, Hailey, Carpenter, Christopher, Markett, Daniel, Corces, M. Ryan, Mardakheh, Faraz K.
Publikováno v:
Nature Communications; 9/9/2024, Vol. 15 Issue 1, p1-21, 21p
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