Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Faraz I, Zaidi"'
Autor:
Ziyang Xu, Susanne Walker, Megan C. Wise, Neethu Chokkalingam, Mansi Purwar, Alan Moore, Edgar Tello-Ruiz, Yuanhan Wu, Sonali Majumdar, Kylie M. Konrath, Abhijeet Kulkarni, Nicholas J. Tursi, Faraz I. Zaidi, Emma L. Reuschel, Ishaan Patel, April Obeirne, Jianqiu Du, Katherine Schultheis, Lauren Gites, Trevor Smith, Janess Mendoza, Kate E. Broderick, Laurent Humeau, Jesper Pallesen, David B. Weiner, Daniel W. Kulp
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
HIV envelope is a target for vaccine development, but induction of broadly neutralizing antibodies has been difficult. Here, the authors show that electroporation with a synthetic DNA vaccine construct allows in vivo production of HIV envelope native
Externí odkaz:
https://doaj.org/article/35ba9a407faa49de8522273b74f5d21c
Autor:
Trevor R. F. Smith, Ami Patel, Stephanie Ramos, Dustin Elwood, Xizhou Zhu, Jian Yan, Ebony N. Gary, Susanne N. Walker, Katherine Schultheis, Mansi Purwar, Ziyang Xu, Jewell Walters, Pratik Bhojnagarwala, Maria Yang, Neethu Chokkalingam, Patrick Pezzoli, Elizabeth Parzych, Emma L. Reuschel, Arthur Doan, Nicholas Tursi, Miguel Vasquez, Jihae Choi, Edgar Tello-Ruiz, Igor Maricic, Mamadou A. Bah, Yuanhan Wu, Dinah Amante, Daniel H. Park, Yaya Dia, Ali Raza Ali, Faraz I. Zaidi, Alison Generotti, Kevin Y. Kim, Timothy A. Herring, Sophia Reeder, Viviane M. Andrade, Karen Buttigieg, Gan Zhao, Jiun-Ming Wu, Dan Li, Linlin Bao, Jiangning Liu, Wei Deng, Chuan Qin, Ami Shah Brown, Makan Khoshnejad, Nianshuang Wang, Jacqueline Chu, Daniel Wrapp, Jason S. McLellan, Kar Muthumani, Bin Wang, Miles W. Carroll, J. Joseph Kim, Jean Boyer, Daniel W. Kulp, Laurent M. P. F. Humeau, David B. Weiner, Kate E. Broderick
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
There is currently no licensed SARS-CoV-2 vaccine. Here, the authors generate an optimized DNA vaccine candidate encoding the SARS-CoV-2 spike antigen, demonstrating induction of specific T cells and neutralizing antibody responses in mice and guinea
Externí odkaz:
https://doaj.org/article/0814bda6deff4859a14eda518fea5941
Autor:
Ami Patel, Jewell N. Walters, Emma L. Reuschel, Katherine Schultheis, Elizabeth Parzych, Ebony N. Gary, Igor Maricic, Mansi Purwar, Zeena Eblimit, Susanne N. Walker, Diana Guimet, Pratik Bhojnagarwala, Opeyemi S. Adeniji, Arthur Doan, Ziyang Xu, Dustin Elwood, Sophia M. Reeder, Laurent Pessaint, Kevin Y. Kim, Anthony Cook, Neethu Chokkalingam, Brad Finneyfrock, Edgar Tello-Ruiz, Alan Dodson, Jihae Choi, Alison Generotti, John Harrison, Nicholas J. Tursi, Viviane M. Andrade, Yaya Dia, Faraz I. Zaidi, Hanne Andersen, Mohamed Abdel-Mohsen, Mark G. Lewis, Kar Muthumani, J. Joseph Kim, Daniel W. Kulp, Laurent M. Humeau, Stephanie J. Ramos, Trevor R.F. Smith, David B. Weiner, Kate E. Broderick
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100420- (2021)
Summary: Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, has had a dramatic global impact on public health and social and economic infrastructures. Here, we assess the immunogenicity and anamnestic protective efficacy in rhesus m
Externí odkaz:
https://doaj.org/article/b251aab9f925454e8c8c047ebbca4faa
Autor:
Ami Patel, Emma L. Reuschel, Ziyang Xu, Faraz I. Zaidi, Kevin Y. Kim, Dana P. Scott, Janess Mendoza, Stephanie Ramos, Regina Stoltz, Friederike Feldmann, Atsushi Okumura, Kimberly Meade-White, Elaine Haddock, Tina Thomas, Rebecca Rosenke, Jamie Lovaglio, Patrick W. Hanley, Greg Saturday, Kar Muthumani, Heinz Feldmann, Laurent M. Humeau, Kate E. Broderick, David B. Weiner
Publikováno v:
JCI Insight, Vol 6, Iss 10 (2021)
Emerging coronaviruses from zoonotic reservoirs, including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have been
Externí odkaz:
https://doaj.org/article/6a1a7018c4ed4003a8f49aaa184d7f1a
Autor:
Pablo Tebas, ShuPing Yang, Jean D. Boyer, Emma L. Reuschel, Ami Patel, Aaron Christensen-Quick, Viviane M. Andrade, Matthew P. Morrow, Kimberly Kraynyak, Joseph Agnes, Mansi Purwar, Albert Sylvester, Jan Pawlicki, Elisabeth Gillespie, Igor Maricic, Faraz I. Zaidi, Kevin Y. Kim, Yaya Dia, Drew Frase, Patrick Pezzoli, Katherine Schultheis, Trevor R.F. Smith, Stephanie J. Ramos, Trevor McMullan, Karen Buttigieg, Miles W. Carroll, John Ervin, Malissa C. Diehl, Elliott Blackwood, Mammen P. Mammen, Jessica Lee, Michael J. Dallas, Ami Shah Brown, Jacqueline E. Shea, J.Joseph Kim, David B. Weiner, Kate E. Broderick, Laurent M. Humeau
Publikováno v:
EClinicalMedicine, Vol 31, Iss , Pp 100689- (2021)
Background: A vaccine against SARS-CoV-2 is of high urgency. Here the safety and immunogenicity induced by a DNA vaccine (INO-4800) targeting the full length spike antigen of SARS-CoV-2 are described. Methods: INO-4800 was evaluated in two groups of
Externí odkaz:
https://doaj.org/article/a9f1cb97a12243469984e15dede48ebe
Autor:
Sophia M. Reeder, Emma L. Reuschel, Mamadou A. Bah, Kun Yun, Nicholas J. Tursi, Kevin Y. Kim, Jacqueline Chu, Faraz I. Zaidi, Ilknur Yilmaz, Robert J. Hart, Benjamin Perrin, Ziyang Xu, Laurent Humeau, David B. Weiner, Ahmed S. I. Aly
Publikováno v:
Vaccines, Vol 8, Iss 1, p 21 (2020)
The need for a malaria vaccine is indisputable. A single vaccine for Plasmodium pre-erythrocytic stages targeting the major sporozoite antigen circumsporozoite protein (CSP) has had partial success. Additionally, CD8+ T cells targeting liver-stage (L
Externí odkaz:
https://doaj.org/article/bf7ea69c369f4f4399d88722a7c17bb4
Autor:
Makan Khoshnejad, Urvi S Zankharia, Hyeree Choi, Sagar B. Kudchodkar, Faraz I. Zaidi, Michelle Ho, David B. Weiner, Karuppiah Muthumani, Alfredo Perales-Puchalt, Joseph Kim, Kenneth E. Ugen
Publikováno v:
Human Vaccines & Immunotherapeutics
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Hepatitis B virus (HBV) causes a potentially life-threatening liver infection that frequently results in life-long chronic infection. HBV is responsible for 887,000 deaths each year, most resulting from chronic liver diseases and hepatocellular carci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e7011f5205972ba3ee37701f210300
https://doi.org/10.1080/21645515.2020.1763686
https://doi.org/10.1080/21645515.2020.1763686
Autor:
Jewell Walters, Brian Nguyen, David B. Weiner, J. Joseph Kim, Trevor R.F. Smith, Abhijeet J Kulkarni, Viviane M Andrade, Alison Generotti, Emma L. Reuschel, Laurent Humeau, Dustin Elwood, Ebony N. Gary, Stephanie Ramos, Arthur Doan, Igor Maricic, Zeena Eblimit, Elizabeth Parzych, Drew Frase, Ami Patel, Katherine Schultheis, Mansi Purwar, Kate E. Broderick, Faraz I. Zaidi, Blake Schouest
Publikováno v:
Vaccine. 40(21)
SUMMARYThe enhanced transmissibility and immune evasion associated with emerging SARS-CoV-2 variants demands the development of next-generation vaccines capable of inducing superior protection amid a shifting pandemic landscape. Since a portion of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7015d84fc8af324e4fc7ad7feded887b
https://pubmed.ncbi.nlm.nih.gov/35428500
https://pubmed.ncbi.nlm.nih.gov/35428500
Autor:
Megan C. Wise, Kristopher Paolino, Deborah Kane, Claude Lamarre, Faraz I. Zaidi, Paul T. Scott, Ajay P. Parikh, Stephen J. Thomas, Young K. Park, Scott White, Sagar B. Kudchodkar, David B. Weiner, Amy R. Castellano, Elizabeth K. Duperret, Trina Racine, Myoung Don Oh, Merlin L. Robb, Hyeree Choi, Kristin Mills, Mark L. Bagarazzi, Jeanine M. May, Joel N. Maslow, Janice Darden, Emma L. Reuschel, Moonsup Jeong, Celine Remigio, Kayvon Modjarrad, Karuppiah Muthumani, Ami Patel, Kevin Kim, Nelson L. Michael, Jean D. Boyer, Hyo Jin Lee, Gary P. Kobinger, Christine C. Roberts
Publikováno v:
The Lancet. Infectious Diseases
Summary Background Middle East respiratory syndrome (MERS) coronavirus causes a highly fatal lower-respiratory tract infection. There are as yet no licensed MERS vaccines or therapeutics. This study (WRAIR-2274) assessed the safety, tolerability, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e51489980a31b45e0c8e31515c200a
https://doi.org/10.1016/s1473-3099(19)30266-x
https://doi.org/10.1016/s1473-3099(19)30266-x
Autor:
Mammen P. Mammen, Pablo Tebas, Joseph Agnes, Mary Giffear, Kimberly A. Kraynyak, Elliott Blackwood, Dinah Amante, Emma L. Reuschel, Mansi Purwar, Aaron Christensen-Quick, Nieman Liu, Viviane M. Andrade, Julie Carter, Gabriella Garufi, Malissa C. Diehl, Albert Sylvester, Matthew P. Morrow, Patrick Pezzoli, Abhijeet J. Kulkarni, Faraz I. Zaidi, Drew Frase, Kevin Liaw, Hedieh Badie, Keiko O. Simon, Trevor R.F. Smith, Stephanie Ramos, Robert Spitz, Robert J. Juba, Jessica Lee, Michael Dallas, Ami Shah Brown, Jacqueline E. Shea, J. Joseph Kim, David B. Weiner, Kate E. Broderick, Jean D. Boyer, Laurent M. Humeau
BackgroundVaccines against SARS-CoV-2 are still urgently needed as only 5% of the global population has been vaccinated. Here we report the safety and immunogenicity of a DNA vaccine (INO-4800) targeting the full-length Spike antigen of SARS-CoV-2 wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65bb33f42e855f7d0b873b47add357f8
https://doi.org/10.1101/2021.05.07.21256652
https://doi.org/10.1101/2021.05.07.21256652
