High-throughput kinome-RNAi screen identifies protein kinase R activator (PACT) as a novel genetic modifier of CUG foci integrity in myotonic dystrophy type 1 (DM1).

Autor: Nafisa Neault, Sean O'Reilly, Aiman Tariq Baig, Julio Plaza-Diaz, Mehrdad Azimi, Faraz Farooq, Stephen D Baird, Alex MacKenzie

Publikováno v: PLoS ONE, Vol 16, Iss 9, p e0256276 (2021)

Myotonic Dystrophy Type 1 (DM1) is the most common form of adult muscular dystrophy (~1:8000). In DM1, expansion of CTG trinucleotide repeats in the 3' untranslated region of the dystrophia myotonica protein kinase (DMPK) gene results in DMPK mRNA ha

Externí odkaz: https://doaj.org/article/d2f4199a57cb4eb1b7f3e8037cd72e1a

Frequency of Anemia in Patients Admitted with Acute Decompensated Heart Failure in Tertiary Care Cardiac Hospital

Autor: Suresh Kumar, Muhammad Asim Shaikh, Faraz Farooq Memon, Sharwan Bhuromal

Publikováno v: Journal of Pharmaceutical Research International. :28-34

Introduction: Anemia is one of the potential comorbid condition in patients with acute decompensated heart failure (ADHF) which is linked to higher morbidity and mortality rates. Worldwide, its prevalence ranges from 4% to >70% in hospitalized patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2857cbfa28dfc07134acf7ee1a0f7725
https://doi.org/10.9734/jpri/2022/v34i39b36245

Mean Levels of B-type Natriuretic Peptide (BNP) in Patients with Mitral Stenosis Caused by Rheumatic Heart Disease

Autor: Nadeem Qamar, Tahir Saghir, Tariq Ashraf, Javed Akbar Sial, Atif Ahmed Khan, Ashok Kumar, Lajpat Rai, Syed Ahsan Raza, Iftikhar Ahmed, Faraz Farooq Memon, Altaf Hussain

Publikováno v: Journal of Pharmaceutical Research International. :96-102

Objective: Mitral stenosis caused by rheumatic heart disease (RHD) is the most common cause of valvular lesion in adults and prevalent in developing countries like Pakistan. Higher natriuretic peptide (BNP) levels can be observed in patients with mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b1a7061edc428c8e21fe37a2916526d
https://doi.org/10.9734/jpri/2021/v33i60a34460

Patients Present with Left Bundle Branch Block and its Cardiac Structure Disease during Trans Thoracic Echocardiography

Autor: Irfan Ali Arbab, Faraz Farooq Memon, Muhammad Rafique, Sharwan Bhuro Mal, Ghulam Kubra, Shazia Rasheed

Publikováno v: Pakistan Journal of Medical and Health Sciences. 16:970-972

Background and Purpose: Left bundle branch block (LBBB) is a communal electrocardiographic (ECG) finding that may or may not be associated with overt heart disease at diagnosis. The current study was performed to determine the clinical picture and st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d90539c15c1381817487387f152b62de
https://doi.org/10.53350/pjmhs22162970

Separating the Wheat from the Chaff: The Use of Upstream Regulator Analysis to Identify True Differential Expression of Single Genes within Transcriptomic Datasets

Autor: Alex MacKenzie, Julio Plaza-Díaz, Faraz Farooq, Jeremiah Hadwen, Sarah C. Schock

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6295, p 6295 (2021)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)

The development of DNA microarray and RNA-sequencing technology has led to an explosion in the generation of transcriptomic differential expression data under a wide range of biologic systems including those recapitulating the monogenic muscular dyst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c87d19f720ebe4ec5ece3b1956efb6f
http://europepmc.org/articles/PMC8231191