Zobrazeno 1 - 10 of 122 pro vyhledávání: '"Farand, J."'
1
Akademický článek
Discovery of GS-2278, a Potent and Selective LPAR1 Antagonist for the Treatment of Idiopathic Pulmonary Fibrosis.
Autor: Tang DT; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Du Z; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Yang KS; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Bestvater BP; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Kaplan J; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Neubig ME; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Olen CL; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Phillips B; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Wang P; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Hudson T; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Marchand B; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Chan J; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Sharma M; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Hu Y; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Matles M; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Nejati E; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Chojnacka M; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Adams C; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Pong C; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Holsapple K; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Budas G; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Tsui V; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Venkataramani C; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Lazerwith SE; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Notte GT; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Watkins WJ; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., McGlinchey E; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Zagorska A; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States., Farand J; Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2024 Nov 21. Date of Electronic Publication: 2024 Nov 21.
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2
Akademický článek
Characterization of a KDM5 small molecule inhibitor with antiviral activity against hepatitis B virus.
Autor: Gilmore SA; Gilead Sciences, Inc., Foster City, California, United States America., Tam D; Gilead Sciences, Inc., Foster City, California, United States America., Cheung TL; Gilead Sciences, Inc., Foster City, California, United States America., Snyder C; Gilead Sciences, Inc., Foster City, California, United States America., Farand J; Gilead Sciences, Inc., Foster City, California, United States America., Dick R; Gilead Sciences, Inc., Foster City, California, United States America., Matles M; Gilead Sciences, Inc., Foster City, California, United States America., Feng JY; Gilead Sciences, Inc., Foster City, California, United States America., Ramirez R; Gilead Sciences, Inc., Foster City, California, United States America., Li L; Gilead Sciences, Inc., Foster City, California, United States America., Yu H; Gilead Sciences, Inc., Foster City, California, United States America., Xu Y; Gilead Sciences, Inc., Foster City, California, United States America., Barnes D; Gilead Sciences, Inc., Foster City, California, United States America., Czerwieniec G; Gilead Sciences, Inc., Foster City, California, United States America., Brendza KM; Gilead Sciences, Inc., Foster City, California, United States America., Appleby TC; Gilead Sciences, Inc., Foster City, California, United States America., Birkus G; Gilead Sciences, Inc., Foster City, California, United States America., Willkom M; Gilead Sciences, Inc., Foster City, California, United States America., Kobayashi T; Gilead Sciences, Inc., Foster City, California, United States America., Paoli E; Gilead Sciences, Inc., Foster City, California, United States America., Labelle M; EpiTherapeutics ApS, Copenhagen, Denmark., Boesen T; EpiTherapeutics ApS, Copenhagen, Denmark.; Novo Nordisk A/S, Bagsvaerd, Denmark., Tay CH; Gilead Sciences, Inc., Foster City, California, United States America., Delaney WE 4th; Gilead Sciences, Inc., Foster City, California, United States America., Notte GT; Gilead Sciences, Inc., Foster City, California, United States America., Schmitz U; Gilead Sciences, Inc., Foster City, California, United States America., Feierbach B; Gilead Sciences, Inc., Foster City, California, United States America.
Publikováno v: PloS one [PLoS One] 2022 Dec 07; Vol. 17 (12), pp. e0271145. Date of Electronic Publication: 2022 Dec 07 (Print Publication: 2022).
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3
Akademický článek
SMC5/6-Mediated Transcriptional Regulation of Hepatitis B Virus and Its Therapeutic Potential.
Autor: Bächer, Johannes1 (AUTHOR) johannes.baecher@stud.uke.uni-hamburg.de, Allweiss, Lena1,2 (AUTHOR) l.allweiss@uke.de, Dandri, Maura1,2 (AUTHOR) m.dandri@uke.de
Publikováno v: Viruses (1999-4915). Nov2024, Vol. 16 Issue 11, p1667. 18p.
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4
Akademický článek
Discovery of Potent and Selective MTH1 Inhibitors for Oncology: Enabling Rapid Target (In)Validation.
Autor: Farand J; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Kropf JE; Gilead Sciences, Inc. 199 East Blaine Street, Seattle, Washington 98102, United States., Blomgren P; Gilead Sciences, Inc. 199 East Blaine Street, Seattle, Washington 98102, United States., Xu J; Gilead Sciences, Inc. 199 East Blaine Street, Seattle, Washington 98102, United States., Schmitt AC; Gilead Sciences, Inc. 199 East Blaine Street, Seattle, Washington 98102, United States., Newby ZE; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Wang T; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Murakami E; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Barauskas O; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Sudhamsu J; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Feng JY; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Niedziela-Majka A; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Schultz BE; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Schwartz K; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Viatchenko-Karpinski S; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Kornyeyev D; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Kashishian A; Gilead Sciences, Inc. 199 East Blaine Street, Seattle, Washington 98102, United States., Fan P; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Chen X; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Lansdon EB; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Ports MO; Gilead Sciences, Inc. 199 East Blaine Street, Seattle, Washington 98102, United States., Currie KS; Gilead Sciences, Inc. 199 East Blaine Street, Seattle, Washington 98102, United States., Watkins WJ; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States., Notte GT; Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States.
Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 Nov 19; Vol. 11 (3), pp. 358-364. Date of Electronic Publication: 2019 Nov 19 (Print Publication: 2020).
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6
Akademický článek
KDM5 family as therapeutic targets in breast cancer: Pathogenesis and therapeutic opportunities and challenges.
Autor: Li, Chang-Yun1,2 (AUTHOR), Wang, Wanhe3 (AUTHOR), Leung, Chung-Hang4,5,6,7 (AUTHOR) duncanleung@um.edu.mo, Yang, Guan-Jun1,2 (AUTHOR) champion2014@126.com, Chen, Jiong1,2 (AUTHOR) chenjiong@nbu.edu.cn
Publikováno v: Molecular Cancer. 5/20/2024, Vol. 23 Issue 1, p1-23. 23p.
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7
Akademický článek
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8
Akademický článek
Recent Trends in the Synthesis and Bioactivity of Coumarin, Coumarin–Chalcone, and Coumarin–Triazole Molecular Hybrids.
Autor: Rohman, Nur1 (AUTHOR) nur.rohman@ui.ac.id, Ardiansah, Bayu1 (AUTHOR) bayu.ardiansah@sci.ui.ac.id, Wukirsari, Tuti1 (AUTHOR), Judeh, Zaher2 (AUTHOR) bayu.ardiansah@sci.ui.ac.id
Publikováno v: Molecules. Mar2024, Vol. 29 Issue 5, p1026. 40p.
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9
Akademický článek
Selectivity switch between FAK and Pyk2: Macrocyclization of FAK inhibitors improves Pyk2 potency.
Autor: Farand J; Department of Medicinal Chemistry, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, USA. Electronic address: Julie.Farand@gilead.com., Mai N; Department of Medicinal Chemistry, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, USA., Chandrasekhar J; Department of Structural Chemistry, Gilead Sciences, Inc., 199 East Blaine Street, Seattle, WA 98102, USA., Newby ZE; Department of Structural Chemistry, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, USA., Van Veldhuizen J; Department of Medicinal Chemistry, Gilead Sciences, Inc., 199 East Blaine Street, Seattle, WA 98102, USA., Loyer-Drew J; Department of Medicinal Chemistry, Gilead Sciences, Inc., 199 East Blaine Street, Seattle, WA 98102, USA., Venkataramani C; Department of Medicinal Chemistry, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, USA., Guerrero J; Department of Medicinal Chemistry, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, USA., Kwok A; Department of Biology, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, USA., Li N; Department of Biology, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, USA., Zherebina Y; Department of Biology, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, USA., Wilbert S; Department of Drug Metabolism, Gilead Sciences, Inc., 199 East Blaine Street, Seattle, WA 98102, USA., Zablocki J; Department of Medicinal Chemistry, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, USA., Phillips G; Department of Medicinal Chemistry, Gilead Sciences, Inc., 199 East Blaine Street, Seattle, WA 98102, USA., Watkins WJ; Department of Medicinal Chemistry, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, USA., Mourey R; Department of Biology, Gilead Sciences, Inc., 199 East Blaine Street, Seattle, WA 98102, USA., Notte GT; Department of Medicinal Chemistry, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, USA.
Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2016 Dec 15; Vol. 26 (24), pp. 5926-5930. Date of Electronic Publication: 2016 Nov 02.
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10
Akademický článek
Current Status and Challenges in Anti-Hepatitis B Virus Agents Based on Inactivation/Inhibition or Elimination of Hepatitis B Virus Covalently Closed Circular DNA.
Autor: Zhuang, An-Qi1 (AUTHOR), Chen, Yan1 (AUTHOR), Chen, Shan-Mei1 (AUTHOR), Liu, Wen-Cheng1 (AUTHOR), Li, Yao1 (AUTHOR), Zhang, Wen-Jie1 (AUTHOR), Wu, Yi-Hang1 (AUTHOR) yihangwu@cjlu.edu.cn
Publikováno v: Viruses (1999-4915). Dec2023, Vol. 15 Issue 12, p2315. 31p.
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