Development of a pseudo-typed virus particle based method to determine the efficacy of virucidal agents

Autor: Jordan Thomas, Farah Mughal, Kelly J. Roper, Aurelia Kotsiri, Wejdan Albalawi, Abdullateef Alshehri, Yugandhar B. S. Reddy, Sayandip Mukherjee, Georgios Pollakis, William A. Paxton, Michael Hoptroff

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Abstract The ongoing Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic has highlighted the threat that viral outbreaks pose to global health. A key tool in the arsenal to prevent and control viral disease outbreaks is disinfection

Externí odkaz: https://doaj.org/article/a37989ac726241ffbe3d975b667de77c

The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data

Autor: Steve O'Hagan, Farah Mughal, Marina Wright Muelas, Philip J. R. Day, Douglas B. Kell

Publikováno v: Scientific Reports
Wright Muelas, M, Mughal, F, O’Hagan, S, Day, P J & Kell, D B 2019, ' The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data ', Scientific Reports, vol. 9, no. 1, 17960 . https://doi.org/10.1038/s41598-019-54288-7
Scientific Reports, Vol 9, Iss 1, Pp 1-21 (2019)
Wright Muelas, M, Mughal, F, O’Hagan, S, Day, P J & Kell, D 2019, ' The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data ', Scientific Reports, vol. 9, no. 1, 17960 . https://doi.org/10.1038/s41598-019-54288-7

We recently introduced the Gini coefficient (GC) for assessing the expression variation of a particular gene in a dataset, as a means of selecting improved reference genes over the cohort (‘housekeeping genes’) typically used for normalisation in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f16b8b6370cbf5fd993e1ef18a065c
http://europepmc.org/articles/PMC6884504

Microfluidic channel-assisted screening of hematopoietic malignancies

Autor: Farah, Mughal, Sara J, Baldock, Ehsan Ghayoor, Karimiani, Nick, Telford, Nicholas J, Goddard, Philip J R, Day

Publikováno v: Genes, chromosomescancer. 53(3)

A simple microfluidic fluorescence in situ hybridization (FISH) device allowing accurate analysis of interphase nuclei in 1 hr in narrow channels is presented. Photolithography and fluorosilicic acid etching were used to fabricate microfluidic channe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::41ac69321c771afc9ec297d42f644429
https://pubmed.ncbi.nlm.nih.gov/24339206