Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Farah F Ammar"'
Autor:
Farah F Ammar, Safwat Abdel-Azeim, Loussinée Zargarian, Zeina Hobaika, Richard G Maroun, Serge Fermandjian
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40223 (2012)
Integration of HIV DNA into host chromosome requires a 3'-processing (3'-P) and a strand transfer (ST) reactions catalyzed by virus integrase (IN). Raltegravir (RAL), commonly used in AIDS therapy, belongs to the family of IN ST inhibitors (INSTIs) a
Externí odkaz:
https://doaj.org/article/c1a13c13fa5d4677bf3f8e0076cc4462
Autor:
Serge Fermandjian, Loussinée Zargarian, Richard G. Maroun, Zeina Hobaika, Safwat Abdel-Azeim, Farah F. Ammar
Publikováno v:
FEBS Open Bio
We recently reported that viral DNA could be the primary target of raltegravir (RAL), an efficient anti-HIV-1 drug, which acts by inhibiting integrase. To elucidate this mechanism, we conducted a comparative analysis of RAL and TB11, a diketoacid aba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5103818dc27033430c66de2b7885f6d
https://doi.org/10.1002/2211-5463.12025
https://doi.org/10.1002/2211-5463.12025
Publikováno v:
Retrovirology
Retrovirology, Vol 9, Iss Suppl 1, p P6 (2012)
Retrovirology, Vol 9, Iss Suppl 1, p P6 (2012)
Aim HIV integrase (IN) is a privileged target for antiviral treatments. These induce the emergence of resistant strains, prompting the search of new drugs. To better understand the relationships between structure and function of IN and identify new a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25268b15a0ef9035d6cfa6cffc254aa5
https://doi.org/10.1186/1742-4690-9-s1-p6
https://doi.org/10.1186/1742-4690-9-s1-p6
Autor:
Serge Fermandjian, Zeina Hobaika, Safwat Abdel-Azeim, Farah F. Ammar, Loussinée Zargarian, Richard G. Maroun
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 7, p e40223 (2012)
PLoS ONE, Vol 7, Iss 7, p e40223 (2012)
Integration of HIV DNA into host chromosome requires a 3'-processing (3'-P) and a strand transfer (ST) reactions catalyzed by virus integrase (IN). Raltegravir (RAL), commonly used in AIDS therapy, belongs to the family of IN ST inhibitors (INSTIs) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b151bc2932b43348ac3cebc145d8dd20
https://doi.org/10.1371/journal.pone.0040223
https://doi.org/10.1371/journal.pone.0040223
Autor:
Puechberty S; Mention Biologie Moléculaire et Cellulaire (BMC), Parcours Immunologie, Master 2 Immunologie Translationnelle et Biothérapies (ITB), Sorbonne Université, Paris, France., Hinan Lassouani T; Mention Biologie Moléculaire et Cellulaire (BMC), Parcours Immunologie, Master 2 Immunologie Translationnelle et Biothérapies (ITB), Sorbonne Université, Paris, France., Ammar F; Mention Biologie Moléculaire et Cellulaire (BMC), Parcours Immunologie, Master 2 Immunologie Translationnelle et Biothérapies (ITB), Sorbonne Université, Paris, France., Dimier-Poisson I; Équipe « Biopharmaceuticals & Microorganisms Against Pathologies », UMR ISP 1282 Université de Tours - INRAE, Faculté de Pharmacie, Tours, France.
Publikováno v:
Medecine sciences : M/S [Med Sci (Paris)] 2024 Jun-Jul; Vol. 40 (6-7), pp. 573-575. Date of Electronic Publication: 2024 Jul 08.
Autor:
Boughter CT; Computational Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892., Chatterjee B; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201., Ohta Y; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201., Gorga K; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201., Blair C; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201., Hill EM; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201., Fasana Z; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201., Adebamowo A; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201., Ammar F; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201., Kosik I; Cellular Biology Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892., Murugan V; Virginia G. Piper Center for Personalized Diagnostics, The Biodesign Institute, Arizona State University, Tempe, AZ 85287., Chen WH; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD 21201., Singh NJ; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201., Meier-Schellersheim M; Computational Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2024 May 22. Date of Electronic Publication: 2024 May 22.